Podcast
Questions and Answers
From which embryonic layers do teeth primarily develop?
From which embryonic layers do teeth primarily develop?
- Oral ectoderm and endoderm
- Oral ectoderm and mesoderm
- Endoderm and ectomesenchyme
- Oral ectoderm and ectomesenchyme (correct)
What is the correct order of the stages of tooth development?
What is the correct order of the stages of tooth development?
- Cap, Bell, Bud
- Bell, Cap, Bud
- Bud, Bell, Cap
- Bud, Cap, Bell (correct)
What is the origin of the dental lamina?
What is the origin of the dental lamina?
- Enamel knot
- Ectomesenchyme
- Oral ectoderm (correct)
- Dental papilla
What is the role of the primary epithelial band in tooth development?
What is the role of the primary epithelial band in tooth development?
In which week of intra-uterine life does tooth development begin?
In which week of intra-uterine life does tooth development begin?
What structures are included within the tooth germ?
What structures are included within the tooth germ?
What is the function of the enamel knot during tooth development?
What is the function of the enamel knot during tooth development?
Which cells differentiate into odontoblasts?
Which cells differentiate into odontoblasts?
What is the composition of predentin?
What is the composition of predentin?
Which structure forms the periodontal ligament, alveolar bone, and cementum?
Which structure forms the periodontal ligament, alveolar bone, and cementum?
What is the composition of enamel?
What is the composition of enamel?
Which of the following best describes the function of the vestibular lamina?
Which of the following best describes the function of the vestibular lamina?
Approximately how many teeth are present in the deciduous dentition?
Approximately how many teeth are present in the deciduous dentition?
Approximately how many teeth are present in the permanent dentition?
Approximately how many teeth are present in the permanent dentition?
Which dental anomaly is characterized by teeth present at birth?
Which dental anomaly is characterized by teeth present at birth?
What is the term for the condition where one or more teeth are absent?
What is the term for the condition where one or more teeth are absent?
What is the term for having more than the normal number of teeth?
What is the term for having more than the normal number of teeth?
In which dental anomaly the enamel is soft and brittle due to hypocalcification?
In which dental anomaly the enamel is soft and brittle due to hypocalcification?
Which of the following characterizes dentinogenesis imperfecta?
Which of the following characterizes dentinogenesis imperfecta?
What is the clinical presentation in dentinogenesis imperfecta?
What is the clinical presentation in dentinogenesis imperfecta?
What can natal teeth potentially cause?
What can natal teeth potentially cause?
Where do supernumerary teeth most commonly develop?
Where do supernumerary teeth most commonly develop?
During which stage of tooth development does the enamel organ form?
During which stage of tooth development does the enamel organ form?
What feature is forming at the Bell stage?
What feature is forming at the Bell stage?
Which component signals the location of the tooth cusp?
Which component signals the location of the tooth cusp?
What is the fate of the dental lamina once tooth development is complete?
What is the fate of the dental lamina once tooth development is complete?
What is the cervical loop?
What is the cervical loop?
What does BMP4 signal to the mesenchyme?
What does BMP4 signal to the mesenchyme?
What does stellate reticulum combine with to create the Enamel organ?
What does stellate reticulum combine with to create the Enamel organ?
Which of the following does the dental follicle NOT form?
Which of the following does the dental follicle NOT form?
What do the ameloblasts secrete?
What do the ameloblasts secrete?
What are natal teeth?
What are natal teeth?
What is the difference between partial and total anodontia?
What is the difference between partial and total anodontia?
Which permanent tooth is most commonly affected by a supernumerary tooth?
Which permanent tooth is most commonly affected by a supernumerary tooth?
What condition causes the teeth to appear yellow to brown in color?
What condition causes the teeth to appear yellow to brown in color?
What condition occurs if the odontoblasts do not differentiate normally during tooth formation?
What condition occurs if the odontoblasts do not differentiate normally during tooth formation?
Why does enamel tend to wear away in patients with, dentinogenesis imperfecta?
Why does enamel tend to wear away in patients with, dentinogenesis imperfecta?
What can result from natal teeth following birth?
What can result from natal teeth following birth?
Why do supernumerary teeth disrupt the position of normal teeth?
Why do supernumerary teeth disrupt the position of normal teeth?
Flashcards
Oral Ectoderm
Oral Ectoderm
Initially, the mouth opening is lined by epithelium.
Ectomesenchyme
Ectomesenchyme
Mesenchyme is a type of animal tissue comprised of cells embedded in a gelatinous matrix.
Permanent vs. Deciduous teeth
Permanent vs. Deciduous teeth
Permanent teeth consist of 32 teeth, while deciduous consists of 20 teeth.
Vestibular lamina
Vestibular lamina
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Dental lamina
Dental lamina
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Stages of tooth development
Stages of tooth development
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Where mesenchyme condenses
Where mesenchyme condenses
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Outer enamel epithelium
Outer enamel epithelium
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Inner enamel epithelium
Inner enamel epithelium
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Components of the Enamel Organ
Components of the Enamel Organ
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Dental Papilla cells
Dental Papilla cells
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Dental follicle
Dental follicle
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Tooth germ
Tooth germ
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Natal teeth
Natal teeth
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Supernumerary teeth
Supernumerary teeth
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Partial anodontia
Partial anodontia
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Total anodontia
Total anodontia
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Amelogenesis imperfecta
Amelogenesis imperfecta
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Dentinogenesis imperfecta
Dentinogenesis imperfecta
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Study Notes
- Tooth development includes the origin of tooth buds, stages of tooth development, formation of the enamel organ, dental papilla and dental follicle/sac, enamel knot, production of enamel, dentin and cementum, and anomalies.
- Tooth development happens from the 6th week of intra-uterine life.
- Development occurs from oral ectoderm through proximate interactions and the ectomesenchyme.
- Deciduous teeth amounts to 20, permanent teeth amount to 32.
- Tooth development occurs from:
- Oral ectoderm (proximate interactions)
- Ectomesenchyme
Primary Epithelial Band
- Vestibular lamina forms the vestibule of the mouth.
- Dental lamina forms the tooth.
Stages of Tooth Development
- Bud stage
- Cap stage
- Bell stage
Dental Lamina
- During tooth eruption, mesenchyme condenses at 10 points in each jaw.
Bud stage
- Illustrated by a tooth bud
Cap Stage
- Requires formation of the dental lamina, enamel organ, and dental papilla
- A combination of outer enamel epithelium, inner enamel epithelium, and stellate reticulum forms the enamel organ.
- The angle between outer enamel epithelium (OEE) and inner enamel epithelium (IEE) forms the cervical loop.
Bell Stage
- Requires the degeneration of dental lamina and formation of the enamel reticulum, dental papilla, and dental sac.
- A tooth germ comprises of enamel organ + dental papilla + dental follicle
Enamel Organ
- Cells of the dental papilla differentiate into odontoblasts, which secrete predentin initially.
- Predentin comprises collagen and ground substance only.
- Dentin comprises collagen, ground substance, and hydroxyapatite crystals (calcium and phosphate).
- Inner enamel epithelium differentiates into ameloblasts, which secrete enamel.
- Enamelin, amelin, tuftelin, and amelogenin are secreted
Developing Teeth
- The dental follicle forms the PDL, alveolar bone and cementum.
Tooth Development
- Anatomic structure of the tooth crown, dental pulp, artery, and root.
Enamel knot
- Requires mesenchyme and for BMP4 to produce a positive signal during the bud stage
- Requires enamel knot in the bell stage.
Tooth Abnormalities
- Natal teeth
- Numerical abnormalities
- Anodontia
- Partial anodontia
- Amelogenesis imperfecta
- Dentinogenesis imperfecta
Natal Teeth
- Teeth present at birth
- It may cause maternal discomfort during breastfeeding, and the infant's tongue could be lacerated.
Numerical Abnormalities
- Involves supernumerary teeth, which develop in the maxillary incisors and disrupt position and eruption of normal teeth
- The extra tooth erupts posterior to the normal ones
Partial Anodontia
- Requires the absence of one or more teeth
Total Anodontia
- Requires no teeth to develop
Amelogenesis Imperfecta
- Enamel is soft and brittle attributed to hypocalcification
- Teeth are yellow to brown in color and appear dark.
- Occurs in a ratio of 1:20,000.
Dentinogenesis Imperfecta
- Teeth are brown to gray blue
- Odontoblasts do not differentiate normally
- Dentin is poorly calcified
- Enamel tends to wear off, exposing the yellow dentin
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