Podcast
Questions and Answers
What type of supply does dentine have?
What type of supply does dentine have?
- Muscle supply
- Nerve supply (correct)
- Bone supply
- Blood supply
Which cells are responsible for dentine formation during the embryonic stage?
Which cells are responsible for dentine formation during the embryonic stage?
- Odontoblasts (correct)
- Hepatoblasts
- Chondroblasts
- Osteoblasts
What is dentine capable of?
What is dentine capable of?
- Digestion
- Respiration
- Reproduction
- Repair (correct)
Which type of supply does dentine lack?
Which type of supply does dentine lack?
What makes dentine sensitive?
What makes dentine sensitive?
What property of enamel allows it to resist elastic deformation?
What property of enamel allows it to resist elastic deformation?
Which of the following characteristics does enamel possess?
Which of the following characteristics does enamel possess?
What effect does a high modulus of elasticity have on enamel?
What effect does a high modulus of elasticity have on enamel?
Which mechanical property is associated with enamel's resistance to elastic deformation?
Which mechanical property is associated with enamel's resistance to elastic deformation?
What would happen if enamel had a low modulus of elasticity?
What would happen if enamel had a low modulus of elasticity?
What is the term used to describe the areas between globules where the fusion may be incomplete?
What is the term used to describe the areas between globules where the fusion may be incomplete?
In which layer, beneath the mantle or root, can the fusion be incomplete resulting in interglobular dentin?
In which layer, beneath the mantle or root, can the fusion be incomplete resulting in interglobular dentin?
What happens if the globules fail to calcify or the areas between them don’t calcify?
What happens if the globules fail to calcify or the areas between them don’t calcify?
What is a characteristic feature of areas with interglobular dentin?
What is a characteristic feature of areas with interglobular dentin?
Which specific layers are mentioned in the text as areas where fusion may be incomplete?
Which specific layers are mentioned in the text as areas where fusion may be incomplete?
What forms a neuro vascular bundle in teeth?
What forms a neuro vascular bundle in teeth?
Where does the neuro vascular bundle enter the tooth from?
Where does the neuro vascular bundle enter the tooth from?
Where do the blood vessels branch profusely to form a plexus?
Where do the blood vessels branch profusely to form a plexus?
Which vessels are NOT involved in forming the neuro vascular bundle?
Which vessels are NOT involved in forming the neuro vascular bundle?
What happens to the neuro vascular bundle as it reaches the crown of the tooth?
What happens to the neuro vascular bundle as it reaches the crown of the tooth?
What is the major GAG that helps facilitate cell migration in developing pulp?
What is the major GAG that helps facilitate cell migration in developing pulp?
Which type of GAG plays a crucial role in cell migration during development?
Which type of GAG plays a crucial role in cell migration during development?
Which glycosaminoglycan (GAG) is primarily involved in aiding cell migration in developing pulp?
Which glycosaminoglycan (GAG) is primarily involved in aiding cell migration in developing pulp?
Which GAG is specifically emphasized for its role in cell migration in developing tissues?
Which GAG is specifically emphasized for its role in cell migration in developing tissues?
What is the predominant glycosaminoglycan (GAG) that aids cell migration during development in pulp?
What is the predominant glycosaminoglycan (GAG) that aids cell migration during development in pulp?
What type of sequence is found in osteopontin that is important for receptor binding?
What type of sequence is found in osteopontin that is important for receptor binding?
Which component of osteopontin is phosphorylated?
Which component of osteopontin is phosphorylated?
Where has osteopontin been identified?
Where has osteopontin been identified?
Which of the following correctly describes the structure of osteopontin?
Which of the following correctly describes the structure of osteopontin?
What function does the receptor binding sequence RGD serve in osteopontin?
What function does the receptor binding sequence RGD serve in osteopontin?
What is the typical width of the mineralization front in dentinogenesis?
What is the typical width of the mineralization front in dentinogenesis?
How would you describe the staining appearance of demineralized H&E sections?
How would you describe the staining appearance of demineralized H&E sections?
Which appearance might the mineralization front show during dentinogenesis?
Which appearance might the mineralization front show during dentinogenesis?
What aspect of enamel is highlighted by its lack of mineralization in demineralized H&E sections?
What aspect of enamel is highlighted by its lack of mineralization in demineralized H&E sections?
In what range is the width of the mineralization front during dentinogenesis?
In what range is the width of the mineralization front during dentinogenesis?
What factor causes variation in width between teeth and within an individual tooth?
What factor causes variation in width between teeth and within an individual tooth?
Which factor contributes to the variations in dentin width within an individual tooth?
Which factor contributes to the variations in dentin width within an individual tooth?
What aspect of a tooth influences the width of dentin?
What aspect of a tooth influences the width of dentin?
In addition to location, what else can cause variation in the width of dentin?
In addition to location, what else can cause variation in the width of dentin?
Which parameter influences the width variations of dentin?
Which parameter influences the width variations of dentin?
What percentage of the dry weight does collagen comprise as the predominant extracellular matrix component?
What percentage of the dry weight does collagen comprise as the predominant extracellular matrix component?
What is the primary component of the extracellular matrix, responsible for 25–32% of the dry weight?
What is the primary component of the extracellular matrix, responsible for 25–32% of the dry weight?
Which component makes up a significant portion of the dry weight and is considered the main constituent of the extracellular matrix?
Which component makes up a significant portion of the dry weight and is considered the main constituent of the extracellular matrix?
In the extracellular matrix, what proportion of the dry weight does collagen predominantly account for?
In the extracellular matrix, what proportion of the dry weight does collagen predominantly account for?
What is the major component of the dry weight in the extracellular matrix?
What is the major component of the dry weight in the extracellular matrix?
What is the defining characteristic of acellular cementum?
What is the defining characteristic of acellular cementum?
In acellular cementum, what separates the hyaline layer from the acellular cementum?
In acellular cementum, what separates the hyaline layer from the acellular cementum?
What type of cementum is found to be structureless without any cells present?
What type of cementum is found to be structureless without any cells present?
Which layer in the tooth consists of acellular cementum with a dark line marking afibrillar cementum?
Which layer in the tooth consists of acellular cementum with a dark line marking afibrillar cementum?
What distinguishes the appearance of acellular cementum from cellular cementum?
What distinguishes the appearance of acellular cementum from cellular cementum?
What is the typical shape of most crystallites in dentin cross sections?
What is the typical shape of most crystallites in dentin cross sections?
Which part of the crystals in dentin is richer in magnesium and carbonate?
Which part of the crystals in dentin is richer in magnesium and carbonate?
What characteristic of the dentin peripheries makes them less soluble when compared to the cores?
What characteristic of the dentin peripheries makes them less soluble when compared to the cores?
What mineral ions are more prominent in the cores of dental crystals?
What mineral ions are more prominent in the cores of dental crystals?
What is the primary factor influencing the solubility differences between the cores and peripheries of dentin crystals?
What is the primary factor influencing the solubility differences between the cores and peripheries of dentin crystals?
Why do odontoblasts appear like multilayered columnar cells in histological sections?
Why do odontoblasts appear like multilayered columnar cells in histological sections?
What is the main reason for odontoblasts being described as pseudostratified columnar cells?
What is the main reason for odontoblasts being described as pseudostratified columnar cells?
In histological sections, what gives odontoblasts the appearance of being multilayered columnar cells?
In histological sections, what gives odontoblasts the appearance of being multilayered columnar cells?
What cellular feature contributes most to odontoblasts resembling multilayered columnar cells?
What cellular feature contributes most to odontoblasts resembling multilayered columnar cells?
What characteristic feature primarily leads to odontoblasts being perceived as multilayered columnar cells?
What characteristic feature primarily leads to odontoblasts being perceived as multilayered columnar cells?
What is a defining characteristic of true denticles according to the text?
What is a defining characteristic of true denticles according to the text?
How are pulp stones typically detected on radiographs?
How are pulp stones typically detected on radiographs?
In the context of pulp stones, what sets true denticles apart from other structures?
In the context of pulp stones, what sets true denticles apart from other structures?
What distinguishes a group of pulp stones from a single pulp stone according to the text?
What distinguishes a group of pulp stones from a single pulp stone according to the text?
Which statement accurately describes the appearance of true denticles on radiographs?
Which statement accurately describes the appearance of true denticles on radiographs?
Why does oblique sectioning result in multiple cell layers appearing above each other?
Why does oblique sectioning result in multiple cell layers appearing above each other?
Which factor primarily influences the width of dentin within an individual tooth?
Which factor primarily influences the width of dentin within an individual tooth?
What leads to the sensitivity of dentin?
What leads to the sensitivity of dentin?
What distinguishes acellular cementum from cellular cementum?
What distinguishes acellular cementum from cellular cementum?
Which aspect of dentine formation during the embryonic stage is highlighted?
Which aspect of dentine formation during the embryonic stage is highlighted?
What receptors do both cementoblasts and osteoblasts have for parathormone (PRT) and parathormone receptor protein (PTHrP)?
What receptors do both cementoblasts and osteoblasts have for parathormone (PRT) and parathormone receptor protein (PTHrP)?
What gland controls the activity of cementoblasts and osteoblasts through the action of parathormone (PRT) and parathormone receptor protein (PTHrP)?
What gland controls the activity of cementoblasts and osteoblasts through the action of parathormone (PRT) and parathormone receptor protein (PTHrP)?
What does the distribution of a vertical force on a tooth surface aim to achieve?
What does the distribution of a vertical force on a tooth surface aim to achieve?
What is the primary function of applying a vertical force on a tooth surface?
What is the primary function of applying a vertical force on a tooth surface?
How can one ensure the long-term functionality of teeth following the application of vertical forces?
How can one ensure the long-term functionality of teeth following the application of vertical forces?
Study Notes
Collagen and Cementum
- Collagen is the main component of the extracellular matrix, making up 25-32% of the dry weight.
- Acellular cementum appears structureless, with no cells.
- There is a dark line between the hyaline layer and acellular cementum, marking the afibrillar cementum.
Dentin Formation
- Odontoblasts are responsible for dentin formation during the embryonic stage.
- Incomplete fusion of globules can lead to areas of interglobular dentin, which are areas between globules.
Blood Vessels and Pulp
- Blood vessels (arterioles and venules) have a close relation with nerves, forming a neurovascular bundle that enters the tooth from the apical foramen and lateral canals.
- Chondroitin sulphate is the major glycosaminoglycan (GAG) in the developing pulp, facilitating cell migration.
- Osteopontin, a phosphorylated glycoprotein, is identified in predentine and contains the receptor binding sequence RGD.
Dentin Characteristics
- Dentin width is around 0.25mm, varying according to location, function, and age.
- Dentin has a distinct pale-staining appearance in demineralized H&E sections due to its lack of mineralization.
- Mineralization front can show a globular or linear appearance (dentinogenesis).
- Dentin crystallites are mostly hexagonal in cross-section, with cores richer in magnesium and carbonate.
Odontoblasts and Pulp Stones
- Odontoblasts appear as multilayered columnar cells (pseudostratified columnar cells) in histological sections.
- Pulp stones can be single or in groups, and can be detected on radiographs.
- True denticles resemble dentine, with a tubular structure.
Hormonal Control
- Cementoblasts and osteoblasts have receptors for parathormone (PRT) and parathormone receptor protein (PTHrP), making them under the control of thyroid and parathyroid glands.
Tooth Structure and Function
- The tooth structure is designed to distribute mechanical force in different directions, reducing the amount of force on the tooth and allowing it to function for a long period.
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Description
Test your knowledge about dentin formation in teeth, including the role of odontoblasts and the repair process. Explore the characteristics of dentin that make it vital, sensitive, and capable of repair.