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Questions and Answers
Several ______ cause disease in animals and humans> symptoms range from rashes, high fever to joint pain and encephalitis
Several ______ cause disease in animals and humans> symptoms range from rashes, high fever to joint pain and encephalitis
togaviruses
______ glycoprotein binds to cellular receptors> receptor mediated endocytosis (e.g. laminin receptor) via clathrin coated vesicles
______ glycoprotein binds to cellular receptors> receptor mediated endocytosis (e.g. laminin receptor) via clathrin coated vesicles
E
Linear ‘+’ sense ssRNA gneome ~9.7-11.8kb and has both 5’ methylated cap and a 3’ poly(A) tail (~70nt)
Linear ‘+’ sense ssRNA gneome ~9.7-11.8kb and has both 5’ methylated cap and a 3’ poly(A) tail (~70nt)
genome
Spherical ______d particle with a fringe of projections (spikes)~ 70nm in diameter
Spherical ______d particle with a fringe of projections (spikes)~ 70nm in diameter
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Once in endosome, pH drop leads to conformational changes in E1/E2 heterodimer> leads to ______ after exposure of ______ domain - Fusion of endosome membrane with viral envelope> release of nucleocapsid
Once in endosome, pH drop leads to conformational changes in E1/E2 heterodimer> leads to ______ after exposure of ______ domain - Fusion of endosome membrane with viral envelope> release of nucleocapsid
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Capsid proteins interact with the cytoplasmic tails of envelope proteins studding the plasma membrane - Virus exits cell by
Capsid proteins interact with the cytoplasmic tails of envelope proteins studding the plasma membrane - Virus exits cell by
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PE2: Precurosr to E2, palmitoylated and glycosylated Capsid: forms
PE2: Precurosr to E2, palmitoylated and glycosylated Capsid: forms
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Structural proteins are
Structural proteins are
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NsP4: RNA
NsP4: RNA
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Virus exits cell by
Virus exits cell by
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