Togaviruses and their Characteristics
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Togaviruses and their Characteristics

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Questions and Answers

What is the size of the togavirus envelope particle?

  • 90nm in diameter
  • 50nm in diameter
  • 120nm in diameter
  • 70nm in diameter (correct)

    • How many copies of capsid proteins are present in the togavirus envelope?

  • 200
  • 120
  • 240 (correct)
  • 180

    • Which cellular receptor does the E glycoprotein of the togavirus bind to?

  • Fibronectin receptor
  • Integrin receptor
  • Laminin receptor (correct)
  • Collagen receptor

    • What is the length of the 3’ poly(A) tail in the togavirus genome?

    <p>~70nt</p> Signup and view all the answers

    What is the role of nsP4 in the viral replication process?

    <p>nsP4 acts as an RNA polymerase</p> Signup and view all the answers

    Which protein is responsible for the fusion of endosome membrane with the viral envelope?

    <p>E1/E2 heterodimer</p> Signup and view all the answers

    What is the function of PE2 in the virus replication cycle?

    <p>Precursor to E2, palmitoylated and glycosylated</p> Signup and view all the answers

    Where are the structural proteins palmitoylated?

    <p>In the Golgi</p> Signup and view all the answers

    Which part of PE2 contains the signal sequence?

    <p>6</p> Signup and view all the answers

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