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Togaviruses and their Characteristics

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Questions and Answers

What is the size of the togavirus envelope particle?

90nm in diameter

50nm in diameter

120nm in diameter

70nm in diameter (correct)

How many copies of capsid proteins are present in the togavirus envelope?

200

120

240 (correct)

180

Which cellular receptor does the E glycoprotein of the togavirus bind to?

Fibronectin receptor

Integrin receptor

Laminin receptor (correct)

Collagen receptor

What is the length of the 3’ poly(A) tail in the togavirus genome?

~70nt (B) Signup and view all the answers

What is the role of nsP4 in the viral replication process?

nsP4 acts as an RNA polymerase (B) Signup and view all the answers

Which protein is responsible for the fusion of endosome membrane with the viral envelope?

E1/E2 heterodimer (D) Signup and view all the answers

What is the function of PE2 in the virus replication cycle?

Precursor to E2, palmitoylated and glycosylated (A) Signup and view all the answers

Where are the structural proteins palmitoylated?

In the Golgi (B) Signup and view all the answers

Which part of PE2 contains the signal sequence?

6 (A) Signup and view all the answers