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What class of drug is Tobramycin?
What class of drug is Tobramycin?
What is the most common route of administration for Tobramycin?
What is the most common route of administration for Tobramycin?
What is the recommended dose of Tobramycin?
What is the recommended dose of Tobramycin?
3-6 mg/kg TID, 4.5 mg/kg BID, should not exceed 9-18 mg/kg/day
What is a therapeutic use of Tobramycin?
What is a therapeutic use of Tobramycin?
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What is the mechanism of action of Tobramycin?
What is the mechanism of action of Tobramycin?
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What are the nursing implications when administering Tobramycin?
What are the nursing implications when administering Tobramycin?
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What are some adverse reactions associated with Tobramycin?
What are some adverse reactions associated with Tobramycin?
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Study Notes
Tobramycin Overview
- Classifies as an aminoglycoside antibiotic, effective against specific bacterial infections.
Administration Routes
- Most commonly administered as an ophthalmic solution.
- Alternative administration routes include intravenous (IV), intramuscular (IM), and inhalation.
Dosage Guidelines
- Standard dosing ranges from 3-6 mg/kg administered three times daily (TID).
- An alternative regimen is 4.5 mg/kg given twice daily (BID).
- Maximum doses should not exceed 9-18 mg/kg per day.
Therapeutic Applications
- Primarily used to treat severe infections caused by gram-negative rods in ocular conditions.
- Demonstrates synergistic effects when used alongside β-lactam antibiotics.
- Ineffective against anaerobic bacteria.
Mechanism of Action
- Functions by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit.
- Prevents bacterial growth and reproduction.
Nursing Implications
- Essential to monitor kidney function to prevent potential nephrotoxicity.
- Watch for signs of hematuria (blood in urine) indicating possible kidney issues.
Adverse Reactions
- Known to cause ototoxicity, leading to hearing impairment and loss of balance.
- May also result in nephrotoxicity, presented as cloudy or bloody urine.
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Description
This quiz covers essential information about Tobramycin, an aminoglycoside antibiotic. It includes details on administration routes, dosage guidelines, therapeutic applications, and its mechanism of action. Test your knowledge on this critical medication and its nursing implications.
