Podcast
Questions and Answers
What is the relationship between the 13910 position genotype and methylation levels at the promoter region?
What is the relationship between the 13910 position genotype and methylation levels at the promoter region?
- Individuals with the T variant have lower methylation levels at the promoter region. (correct)
- Individuals with the C variant have lower methylation levels at the promoter region.
- Individuals with the C variant have higher methylation levels at the promoter region.
- Individuals with the T variant have higher methylation levels at the promoter region.
What happens to lactase expression levels after weaning?
What happens to lactase expression levels after weaning?
- Lactase expression remains unchanged.
- Lactase expression increases due to dietary changes.
- Lactase expression decreases due to absence of lactose.
- Lactase expression decreases due to methylation at the enhancer site. (correct)
Which factor appears to be continuously associated with lactase phenotypes in the text?
Which factor appears to be continuously associated with lactase phenotypes in the text?
- Gut flora composition
- Absence of lactose
- Dietary intake of lactose
- Methylation levels at the enhancer site (correct)
How does the genotype at the 13910 position affect methylation levels at the enhancer site?
How does the genotype at the 13910 position affect methylation levels at the enhancer site?
What role does dietary change or lactose intake play in increasing lactase production?
What role does dietary change or lactose intake play in increasing lactase production?
What may be a potential reason for differences in symptoms among lactase non-persistent individuals?
What may be a potential reason for differences in symptoms among lactase non-persistent individuals?
How do multiple independent mutations relate to various populations?
How do multiple independent mutations relate to various populations?
Which factor outperforms the previously known genotype in predicting lactase persistence vs. lactase non-persistence phenotype?
Which factor outperforms the previously known genotype in predicting lactase persistence vs. lactase non-persistence phenotype?
How does having the T variant in the -13910 position affect CpG site methylation at the enhancer?
How does having the T variant in the -13910 position affect CpG site methylation at the enhancer?
What is the role of the enhancer region in the context of lactase persistence?
What is the role of the enhancer region in the context of lactase persistence?
How do SNP variants contribute to lactase persistence?
How do SNP variants contribute to lactase persistence?
Why is it significant that individuals with a lactase persistence SNP at one position have a non-persistent SNP at others?
Why is it significant that individuals with a lactase persistence SNP at one position have a non-persistent SNP at others?
How do mutations contribute to the evolution of new traits like lactase persistence?
How do mutations contribute to the evolution of new traits like lactase persistence?
What is the significance of having the variant T at the -13910 position in the enhancer region?
What is the significance of having the variant T at the -13910 position in the enhancer region?
How do SNPs at the enhancer region influence LCT enzyme activity?
How do SNPs at the enhancer region influence LCT enzyme activity?
What does the study suggest about individuals with different genotypes at the -13910 site?
What does the study suggest about individuals with different genotypes at the -13910 site?
How does having different genotypes at the -13910 site influence DNA methylation levels?
How does having different genotypes at the -13910 site influence DNA methylation levels?
How does the presence of SNP variant T enhance gene expression at the MCM6 region?
How does the presence of SNP variant T enhance gene expression at the MCM6 region?
What is the impact of having a C instead of a T at the position that allows activator binding?
What is the impact of having a C instead of a T at the position that allows activator binding?
What is the genetic basis for lactase persistence mentioned in the text?
What is the genetic basis for lactase persistence mentioned in the text?
Why did lactase persistence become a common trait in some populations?
Why did lactase persistence become a common trait in some populations?
What happens to potentially lactase persistent gene variants if there is no selective advantage for them?
What happens to potentially lactase persistent gene variants if there is no selective advantage for them?
How are gene variations typically originated according to the text?
How are gene variations typically originated according to the text?
Which process leads to the elimination of mutations that do not offer a selective advantage in a population?
Which process leads to the elimination of mutations that do not offer a selective advantage in a population?
What is the significance of maintaining affinity between activator and enhancer for the LCT gene?
What is the significance of maintaining affinity between activator and enhancer for the LCT gene?
