Podcast
Questions and Answers
What autoimmune thyroid disorder results in thyrotoxicosis (hyperthyroidism)?
What autoimmune thyroid disorder results in thyrotoxicosis (hyperthyroidism)?
- Thyroid cancer
- Cushing's syndrome
- Hashimoto’s disease
- Graves` disease (correct)
Which hormone is usually targeted by autoantibodies in autoimmune thyroid disorders like Graves` disease and Hashimoto’s disease?
Which hormone is usually targeted by autoantibodies in autoimmune thyroid disorders like Graves` disease and Hashimoto’s disease?
- PTH
- FSH
- TSHR (correct)
- TRH
What characteristic symptom distinguishes Graves` disease from Hashimoto’s disease?
What characteristic symptom distinguishes Graves` disease from Hashimoto’s disease?
- Bradycardia
- Protrusion of the eyeballs (exophthalmos) (correct)
- Sensitivity to cold
- Myxedema
Which medication for hyperthyroidism emits both gamma rays for diagnostic imaging and beta particles for therapy?
Which medication for hyperthyroidism emits both gamma rays for diagnostic imaging and beta particles for therapy?
What is the major immunological origin of hypothyroidism, resulting in symptoms like slow speech and mental impairment?
What is the major immunological origin of hypothyroidism, resulting in symptoms like slow speech and mental impairment?
What is the role of Dio2 in relation to thyroid hormones?
What is the role of Dio2 in relation to thyroid hormones?
Which enzyme catalyzes the metabolic inactivation of T3?
Which enzyme catalyzes the metabolic inactivation of T3?
What is the effect of T3 on heart rate?
What is the effect of T3 on heart rate?
Which thyroid hormone receptor is responsible for inducing hypocholesterolemia?
Which thyroid hormone receptor is responsible for inducing hypocholesterolemia?
What is the function of Resmetirom in relation to thyroid hormone receptors?
What is the function of Resmetirom in relation to thyroid hormone receptors?
What adverse effect can occur upon chronic overdose of thyroid hormones?
What adverse effect can occur upon chronic overdose of thyroid hormones?
Which thyroid hormone has a faster onset but shorter duration of action than T4?
Which thyroid hormone has a faster onset but shorter duration of action than T4?
What is the risk associated with chronic overdose of thyroid hormones?
What is the risk associated with chronic overdose of thyroid hormones?
Which of the following foods can block iodine uptake by the thyroid?
Which of the following foods can block iodine uptake by the thyroid?
Which condition is liothyronine (T3) generally reserved for treating?
Which condition is liothyronine (T3) generally reserved for treating?
What is the primary hormone secreted by the thyroid gland?
What is the primary hormone secreted by the thyroid gland?
What is the main function of thyroid follicles?
What is the main function of thyroid follicles?
Which hormone is more active and why?
Which hormone is more active and why?
Which hormones inhibit the secretion of TRH and TSH?
Which hormones inhibit the secretion of TRH and TSH?
What is the role of tissue (peripheral) 5`-deiodinase in the thyroid hormone system?
What is the role of tissue (peripheral) 5`-deiodinase in the thyroid hormone system?
What is the mechanism of action for iodine (I2) in temporarily inhibiting the release of thyroid hormones?
What is the mechanism of action for iodine (I2) in temporarily inhibiting the release of thyroid hormones?
What effect do estrogens and the state of pregnancy have on plasma protein binding of T4?
What effect do estrogens and the state of pregnancy have on plasma protein binding of T4?
Which drug affects thyroid function by releasing a large amount of iodine?
Which drug affects thyroid function by releasing a large amount of iodine?
What is the main use of strong iodine solution (Lugol solution) and potassium iodide saturated solution (KISS)?
What is the main use of strong iodine solution (Lugol solution) and potassium iodide saturated solution (KISS)?
How does propylthiouracil differ from methimazole in its anti-thyroid activity?
How does propylthiouracil differ from methimazole in its anti-thyroid activity?
Which deiodinase is responsible for converting T4 to T3?
Which deiodinase is responsible for converting T4 to T3?
Which of the following is NOT a function of iodine in the thyroid gland?
Which of the following is NOT a function of iodine in the thyroid gland?
What is the role of thyroperoxidase (TPO) in the production of thyroid hormones?
What is the role of thyroperoxidase (TPO) in the production of thyroid hormones?
What effect does lithium have on thyroid function?
What effect does lithium have on thyroid function?
Which of the following substances is NOT a thiourylene or thionamide?
Which of the following substances is NOT a thiourylene or thionamide?
What is the role of the thyroid follicle in thyroid hormone production?
What is the role of the thyroid follicle in thyroid hormone production?
How is the storage and release of thyroid hormones different from other hormones?
How is the storage and release of thyroid hormones different from other hormones?
What is the effect of propylthiouracil on deiodination?
What is the effect of propylthiouracil on deiodination?
What is the structure-activity relationship of thyroid hormones?
What is the structure-activity relationship of thyroid hormones?
What is the difference between T4 and T3 in terms of structure?
What is the difference between T4 and T3 in terms of structure?
Which drug can be used as a substitute for Amiodarone in some cases?
Which drug can be used as a substitute for Amiodarone in some cases?
What is the effect of iodine deficiency on Amiodarone-induced thyroid function?
What is the effect of iodine deficiency on Amiodarone-induced thyroid function?
How does the level of free thyroid hormones affect metabolic activity?
How does the level of free thyroid hormones affect metabolic activity?
What is the structure-activity relationship of thyroid hormones?
What is the structure-activity relationship of thyroid hormones?
How does negative feedback control regulate thyroid hormone production?
How does negative feedback control regulate thyroid hormone production?
Why is propylthiouracil indicated for pregnant hyperthyroid patients during the first trimester?
Why is propylthiouracil indicated for pregnant hyperthyroid patients during the first trimester?
Which adverse effect is more common with methimazole treatment for Graves' disease?
Which adverse effect is more common with methimazole treatment for Graves' disease?
What is the function of β-blockers without intrinsic sympathomimetic activity in the treatment of hyperthyroidism?
What is the function of β-blockers without intrinsic sympathomimetic activity in the treatment of hyperthyroidism?
Why is methimazole preferred over propylthiouracil for regular Graves' disease treatment?
Why is methimazole preferred over propylthiouracil for regular Graves' disease treatment?
Which symptom is NOT typically reduced by β-blockers without intrinsic sympathomimetic activity in hyperthyroid patients?
Which symptom is NOT typically reduced by β-blockers without intrinsic sympathomimetic activity in hyperthyroid patients?
Which drug can lead to hypothyroidism by decreasing thyroid hormone secretion?
Which drug can lead to hypothyroidism by decreasing thyroid hormone secretion?
What is the effect of estrogens on plasma protein binding of T4?
What is the effect of estrogens on plasma protein binding of T4?
What symptom might be expected in a patient with amiodarone-induced hyperthyroidism?
What symptom might be expected in a patient with amiodarone-induced hyperthyroidism?
Which deiodinase enzyme is responsible for converting T4 to T3?
Which deiodinase enzyme is responsible for converting T4 to T3?
How does Amiodarone affect thyroid function in people with normal or slightly high iodine intake?
How does Amiodarone affect thyroid function in people with normal or slightly high iodine intake?
Why are β1-selective β-blockers without ISA preferred in certain cases?
Why are β1-selective β-blockers without ISA preferred in certain cases?
Which type of agents are CONTRAINDICATED in hyperthyroidism?
Which type of agents are CONTRAINDICATED in hyperthyroidism?
Why are anti-thyroid drugs considered useless in the treatment of Exophthalmos of hyperthyroidism/Thyroid eye disease (TED)?
Why are anti-thyroid drugs considered useless in the treatment of Exophthalmos of hyperthyroidism/Thyroid eye disease (TED)?
What is the role of Teprotumumab in treating Thyroid eye disease (TED)?
What is the role of Teprotumumab in treating Thyroid eye disease (TED)?
Why are β-blockers considered NOT useful in treating Exophthalmos of hyperthyroidism/Thyroid eye disease (TED)?
Why are β-blockers considered NOT useful in treating Exophthalmos of hyperthyroidism/Thyroid eye disease (TED)?
Which medication is generally reserved for acute emergencies related to thyroid function?
Which medication is generally reserved for acute emergencies related to thyroid function?
Which autoimmune thyroid disorder results in thyrotoxicosis (hyperthyroidism)?
Which autoimmune thyroid disorder results in thyrotoxicosis (hyperthyroidism)?
Which of the following is a characteristic symptom of Graves' disease?
Which of the following is a characteristic symptom of Graves' disease?
Which medication for hyperthyroidism can also be used for diagnostic imaging of the thyroid gland?
Which medication for hyperthyroidism can also be used for diagnostic imaging of the thyroid gland?
Which food can block iodine uptake by the thyroid, leading to hypothyroidism?
Which food can block iodine uptake by the thyroid, leading to hypothyroidism?
Which of the following is a common symptom of hypothyroidism?
Which of the following is a common symptom of hypothyroidism?
Which of the following is NOT a symptom of hypothyroidism?
Which of the following is NOT a symptom of hypothyroidism?
What is the effect of chronic overdose of thyroid hormones?
What is the effect of chronic overdose of thyroid hormones?
Which autoimmune thyroid disorder results in hypothyroidism?
Which autoimmune thyroid disorder results in hypothyroidism?
Which of the following is a contraindication for radioiodine (131I) therapy?
Which of the following is a contraindication for radioiodine (131I) therapy?
Which medication is a selective TRβ agonist and was recently approved for the treatment of non-alcoholic steatohepatitis (NASH) and NASH-associated liver fibrosis?
Which medication is a selective TRβ agonist and was recently approved for the treatment of non-alcoholic steatohepatitis (NASH) and NASH-associated liver fibrosis?
Which hormone is targeted by autoantibodies in Graves' disease, leading to thyrotoxicosis (hyperthyroidism)?
Which hormone is targeted by autoantibodies in Graves' disease, leading to thyrotoxicosis (hyperthyroidism)?
Which hormone receptor is responsible for inducing hypocholesterolemia by expressing hepatic LDL receptors and reducing apolipoprotein B levels and circulating LDL-cholesterol levels?
Which hormone receptor is responsible for inducing hypocholesterolemia by expressing hepatic LDL receptors and reducing apolipoprotein B levels and circulating LDL-cholesterol levels?
Which thyroid hormone has a slower onset and longer duration of action compared to T3?
Which thyroid hormone has a slower onset and longer duration of action compared to T3?
Which hormones inhibit the secretion of TRH and TSH?
Which hormones inhibit the secretion of TRH and TSH?
Which medication is mainly used for the preparation of hyperthyroid subjects for surgical resection of the gland?
Which medication is mainly used for the preparation of hyperthyroid subjects for surgical resection of the gland?
Which medication is used as part of the treatment of severe thyrotoxic crisis or 'thyroid storm'?
Which medication is used as part of the treatment of severe thyrotoxic crisis or 'thyroid storm'?
Which medication acts faster in reducing the de-iodination of T4 to T3?
Which medication acts faster in reducing the de-iodination of T4 to T3?
Which medication can be used to block the uptake of radioactive iodine into the thyroid in the event of a radiation emergency?
Which medication can be used to block the uptake of radioactive iodine into the thyroid in the event of a radiation emergency?
Which medication can be used to reduce the vascularity of the thyroid gland, making it smaller and firmer?
Which medication can be used to reduce the vascularity of the thyroid gland, making it smaller and firmer?
Which medication is not chemically related to thiourea and does not have a thiocarbamide (S=C–N) group essential for anti-thyroid activity?
Which medication is not chemically related to thiourea and does not have a thiocarbamide (S=C–N) group essential for anti-thyroid activity?
Which medication can be used in the treatment of severe thyrotoxic crisis, also known as 'thyroid storm'?
Which medication can be used in the treatment of severe thyrotoxic crisis, also known as 'thyroid storm'?
Which medication can be used to inhibit the release of thyroid hormones by temporarily inhibiting the release of thyroid hormones?
Which medication can be used to inhibit the release of thyroid hormones by temporarily inhibiting the release of thyroid hormones?
Which medication can be used to reduce the de-iodination of T4 to T3 in peripheral tissues by inhibiting tissue 5'-deiodinase?
Which medication can be used to reduce the de-iodination of T4 to T3 in peripheral tissues by inhibiting tissue 5'-deiodinase?
Which medication can be used to inhibit iodination of TG-bound Tyr residues by reducing H2O2 availability to TPO?
Which medication can be used to inhibit iodination of TG-bound Tyr residues by reducing H2O2 availability to TPO?
What is a potential adverse effect of chronic overdose of thyroid hormones?
What is a potential adverse effect of chronic overdose of thyroid hormones?
Which autoimmune thyroid disorder is characterized by symptoms such as exophthalmos and goiter?
Which autoimmune thyroid disorder is characterized by symptoms such as exophthalmos and goiter?
Which symptom is common in hypothyroidism but not typically seen in hyperthyroidism?
Which symptom is common in hypothyroidism but not typically seen in hyperthyroidism?
Which thyroid medication is generally reserved for the treatment of acute emergencies like myxedema coma?
Which thyroid medication is generally reserved for the treatment of acute emergencies like myxedema coma?
What is a potential consequence of iodine deficiency on thyroid hormone synthesis?
What is a potential consequence of iodine deficiency on thyroid hormone synthesis?
What is the mechanism of action of lithium in affecting thyroid function?
What is the mechanism of action of lithium in affecting thyroid function?
Which enzyme is responsible for converting T4 to T3 in euthyroid individuals?
Which enzyme is responsible for converting T4 to T3 in euthyroid individuals?
What is the effect of Amiodarone on thyroid function in individuals with normal or slightly high iodine intake?
What is the effect of Amiodarone on thyroid function in individuals with normal or slightly high iodine intake?
Which deiodinase enzyme is a plasma membrane protein and is upregulated in hyperthyroidism?
Which deiodinase enzyme is a plasma membrane protein and is upregulated in hyperthyroidism?
What symptom might be observed in a patient with Amiodarone-induced hyperthyroidism despite lacking classic symptoms of cardiac stimulation?
What symptom might be observed in a patient with Amiodarone-induced hyperthyroidism despite lacking classic symptoms of cardiac stimulation?
Which medication for hyperthyroidism emits both gamma rays for diagnostic imaging and beta particles for therapy?
Which medication for hyperthyroidism emits both gamma rays for diagnostic imaging and beta particles for therapy?
Which autoimmune thyroid disorder results in thyrotoxicosis (hyperthyroidism)?
Which autoimmune thyroid disorder results in thyrotoxicosis (hyperthyroidism)?
Which medication can be used to reduce the de-iodination of T4 to T3 in peripheral tissues by inhibiting tissue 5'-deiodinase?
Which medication can be used to reduce the de-iodination of T4 to T3 in peripheral tissues by inhibiting tissue 5'-deiodinase?
What is the main use of strong iodine solution (Lugol solution) and potassium iodide saturated solution (KISS)?
What is the main use of strong iodine solution (Lugol solution) and potassium iodide saturated solution (KISS)?
Which deiodinase enzyme is responsible for converting T4 to T3?
Which deiodinase enzyme is responsible for converting T4 to T3?
Which medication is NOT chemically related to thiourea and does not have a thiocarbamide (S=C–N) group essential for anti-thyroid activity?
Which medication is NOT chemically related to thiourea and does not have a thiocarbamide (S=C–N) group essential for anti-thyroid activity?
Which autoimmune thyroid disorder results in hypothyroidism, causing symptoms like slow speech and mental impairment?
Which autoimmune thyroid disorder results in hypothyroidism, causing symptoms like slow speech and mental impairment?
Which medication is generally reserved for acute emergencies related to thyroid function, such as severe thyrotoxic crisis or 'thyroid storm'?
Which medication is generally reserved for acute emergencies related to thyroid function, such as severe thyrotoxic crisis or 'thyroid storm'?
Which medication for hyperthyroidism emits both gamma rays for diagnostic imaging and beta particles for therapy?
Which medication for hyperthyroidism emits both gamma rays for diagnostic imaging and beta particles for therapy?
Which symptom is NOT typically reduced by β-blockers without intrinsic sympathomimetic activity in hyperthyroid patients?
Which symptom is NOT typically reduced by β-blockers without intrinsic sympathomimetic activity in hyperthyroid patients?
Which medication can be used to reduce the de-iodination of T4 to T3 in peripheral tissues by inhibiting tissue 5'-deiodinase?
Which medication can be used to reduce the de-iodination of T4 to T3 in peripheral tissues by inhibiting tissue 5'-deiodinase?
Which type of agents are CONTRAINDICATED in hyperthyroidism?
Which type of agents are CONTRAINDICATED in hyperthyroidism?
What is the effect of T3 on heart rate?
What is the effect of T3 on heart rate?
What symptom might be expected in a patient with amiodarone-induced hyperthyroidism?
What symptom might be expected in a patient with amiodarone-induced hyperthyroidism?
Which of the following is NOT a symptom of hypothyroidism?
Which of the following is NOT a symptom of hypothyroidism?
Which thyroid hormone receptor is responsible for inducing hypocholesterolemia by expressing hepatic LDL receptors and reducing apolipoprotein B levels and circulating LDL-cholesterol levels?
Which thyroid hormone receptor is responsible for inducing hypocholesterolemia by expressing hepatic LDL receptors and reducing apolipoprotein B levels and circulating LDL-cholesterol levels?
Which of the following drugs is used as part of the treatment of severe thyrotoxic crisis or 'thyroid storm'?
Which of the following drugs is used as part of the treatment of severe thyrotoxic crisis or 'thyroid storm'?
Which of the following autoimmune thyroid disorders results in thyrotoxicosis (hyperthyroidism)?
Which of the following autoimmune thyroid disorders results in thyrotoxicosis (hyperthyroidism)?
Which of the following is a common symptom of hypothyroidism?
Which of the following is a common symptom of hypothyroidism?
Which hormone is targeted by autoantibodies in Graves' disease, leading to thyrotoxicosis (hyperthyroidism)?
Which hormone is targeted by autoantibodies in Graves' disease, leading to thyrotoxicosis (hyperthyroidism)?
Which medication acts faster than methimazole in reducing the de-iodination of T4 to T3 in peripheral tissues?
Which medication acts faster than methimazole in reducing the de-iodination of T4 to T3 in peripheral tissues?
What medication is generally reserved for the acute treatment of thyroid storm?
What medication is generally reserved for the acute treatment of thyroid storm?
What is the adult dose of iodine recommended every 24 hours?
What is the adult dose of iodine recommended every 24 hours?
Which medication is chemically related to thiourea and has an essential thiocarbamide group for its anti-thyroid activity?
Which medication is chemically related to thiourea and has an essential thiocarbamide group for its anti-thyroid activity?
Which medication is mainly used for preparing hyperthyroid subjects for surgical gland resection?
Which medication is mainly used for preparing hyperthyroid subjects for surgical gland resection?
Which medication is available over-the-counter for radiation emergencies to block uptake of radioactive iodine into the thyroid?
Which medication is available over-the-counter for radiation emergencies to block uptake of radioactive iodine into the thyroid?
How does potassium iodide saturated solution impact the thyroid hormone system?
How does potassium iodide saturated solution impact the thyroid hormone system?
