22 Questions
What is the classic variant of papillary thyroid carcinoma characterized by?
BRAF V600E
What are the culprit antibodies in Hashimoto thyroiditis?
Antithyroid peroxidase and antithyroglobulin
What gene mutation is associated with adrenal cortical carcinoma?
Insulin-like growth factor 2 (IGF2) overexpression
What is the main cause of iodine deficiency-related goiter?
Increase in TSH secretion
What is the result of the secretion of fluids from the lining epithelial cells in a thyroglossal duct cyst?
Cystic dilation
What risk factor is best established for papillary thyroid carcinoma?
Ionizing radiation
What are the histological hallmarks of papillary thyroid carcinoma?
Fingerlike projections, nuclear features like inclusion bodies, and abundant mitosis
What is the cardinal feature of pheochromocytoma?
Often sporadic but can be associated with genetic syndromes
What is the most common cause of hypothyroidism?
Hashimoto thyroiditis
What are the nuclear features seen in adrenal cortical carcinoma?
Large cells with granular clear to eosinophilic cytoplasm, pleomorphism, inclusion bodies
What is the only normal remnant of the thyroglossal duct?
The pyramidal lobe of the thyroid gland
What diagnostic method is important for thyroglossal duct cyst?
Scintigraphy
What is the first described name associated with Hashimoto thyroiditis?
Hakaru Hashimoto
What is the most common developmental anomaly of the thyroid gland?
Thyroglossal duct cyst
What is the gender predilection for Adrenal cortical carcinoma?
More common in females
What is the mean age range for the diagnosis of Adrenal cortical carcinoma?
30-40 years old
Which gene mutation is associated with Diffuse Gastric Adenocarcinoma?
CDH1 gene
In Hashimoto thyroiditis, what causes oxidative damage to follicular cells?
Normal TSH
What is the most common type of thyroid cancer?
Papillary thyroid carcinoma
What is the mechanism of thyroid failure in Hashimoto thyroiditis?
Autoimmune destruction
What is the common gender ratio for Multinodular goiter?
More common in females
Which condition may lead to compression of adjacent structures in the neck?
Nodular neck mass
Explore various thyroid disorders including Thyroglossal Duct Cyst, Follicular Adenoma, Papillary Thyroid Carcinoma, and Multinodular Goiter. Learn about their respective organ/site involvements, etiology, and gene mutations associated with these conditions.
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