Thrombosis and Thromboembolism VCS 84610 Quiz
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Questions and Answers

What are the factors that contribute to the formation of arterial thrombosis?

  • Stagnant flow and fibrin-rich/platelet-poor embolus
  • High-shear flow and platelet-rich thrombus (correct)
  • Enhanced thrombolysis and reduced platelet function
  • Reduced clotting factors and excessive clotting factors

    • Which type of thrombosis involves a thrombus forming at a distant site from the original clot location?

  • Venous Thromboembolism (VTE/PE) (correct)
  • Arterial Thrombosis (AT)
  • Venous Thrombosis (DVT)
  • Arterial Thromboembolism (ATE)

    • According to Virchow’s Triangle, which factor is one of the contributors to thrombosis?

  • Endothelial injury
  • Blood stasis (correct)
  • Enhanced thrombolysis
  • Reduced platelet function

    • What is unique about the composition of an embolus in arterial thromboembolism?

    <p>Fibrin-rich/platelet-poor embolus</p> Signup and view all the answers

    Which type of thrombosis involves a thrombus that may form at the site of vascular injury?

    <p>Venous Thrombosis (DVT)</p> Signup and view all the answers

    What is the significance of hypercoagulability in the physiology of thrombosis?

    <p>It increases the risk of clot formation</p> Signup and view all the answers

    What is the primary mechanism of action of aspirin as an antiplatelet drug?

    <p>Inhibits cyclooxygenase</p> Signup and view all the answers

    Which breed of cat has the highest relative risk for hypercoagulability?

    <p>Maine Coon</p> Signup and view all the answers

    What is the primary effect of low molecular weight heparins (LMWHs) on coagulation?

    <p>Inhibit factor Xa</p> Signup and view all the answers

    Which of the following is NOT a potential sequelae of aortic trifurcation embolism in cats?

    <p>Hematuria</p> Signup and view all the answers

    What is the recommended initial dosage of clopidogrel for dogs with cardiogenic embolism?

    <p>10 mg/kg PO at presentation</p> Signup and view all the answers

    Which of the following is a potential clinical sign of pulmonary embolism in dogs?

    <p>Vomiting and diarrhea</p> Signup and view all the answers

    What should be considered to reduce continued thrombus formation in the acute management of cardiogenic embolism?

    <p>Begin anticoagulation with LMWH</p> Signup and view all the answers

    What is the most common cause of death in the acute period of cardiogenic embolism?

    <p>Reperfusion injury</p> Signup and view all the answers

    Which factor does aspirin NOT affect in its mechanism of action as an antiplatelet drug?

    <p>Protein C activation</p> Signup and view all the answers

    Which anticoagulant has high variability in pharmacodynamic response and requires monitoring with PT/INR?

    <p>Warfarin</p> Signup and view all the answers

    What is a characteristic feature of arterial thrombosis?

    <p>High-shear flow</p> Signup and view all the answers

    Which factor contributes to the physiology of thrombosis according to Virchow's Triangle?

    <p>Hypercoagulability</p> Signup and view all the answers

    What is a key difference between venous thrombosis and arterial thrombosis?

    <p>Fibrin-rich/platelet-poor embolus in venous thrombosis</p> Signup and view all the answers

    What type of thromboembolism involves an embolus obstructing a normal vessel at a distant site?

    <p>Arterial Thromboembolism (ATE)</p> Signup and view all the answers

    Which condition is associated with reduced regulation of clotting factors?

    <p>Excessive clotting factors</p> Signup and view all the answers

    What is the primary mechanism of action of clopidogrel as an antiplatelet drug?

    <p>Antagonizes ADP receptors</p> Signup and view all the answers

    Which breed of cat has the second-highest relative risk for hypercoagulability according to the provided text?

    <p>Tonkinese</p> Signup and view all the answers

    What is the primary effect of vitamin K antagonists like warfarin on coagulation factors?

    <p>Inhibits Factor II</p> Signup and view all the answers

    Which of the following clinical conditions is NOT associated with platelet hyperreactivity according to the text?

    <p>Hyperadrenocorticism</p> Signup and view all the answers

    Which anticoagulant does NOT primarily inhibit thrombin (IIa) but instead primarily inhibits Xa through ATIII?

    <p>Low Molecular Weight Heparins (LMWH)</p> Signup and view all the answers

    What are the primary sequelae of aortic trifurcation (saddle thrombus) embolism in cats?

    <p>Ischemic neuromyopathy and pulmonary embolism</p> Signup and view all the answers

    What is the recommended initial dosage of enoxaparin, a Low Molecular Weight Heparin (LMWH), in dogs for thrombosis treatment?

    <p>1 mg/kg SQ q 12-24 hr</p> Signup and view all the answers

    What is the primary complication that can result from a sudden resumption in blood flow to ischemic tissues, known as reperfusion injury?

    <p>Tissue necrosis</p> Signup and view all the answers

    What is a potential treatment option to increase collateral flow in cats with cardiogenic embolism?

    <p>Nitroglycerine ointment</p> Signup and view all the answers

    What is one significant difference between clopidogrel and aspirin as antiplatelet drugs based on the text?

    <p>Clopidogrel has no effect on thromboxane A2 production while aspirin does.</p> Signup and view all the answers

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