BioChem 3: Acids and Bases

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32 Questions

Which of the following is an example of a strong acid?

HCl

Which of the following equations represents the ionization of HCl in water?

HCl -> H+ + Cl-

What is the pH of a solution with a concentration of HCl of 0.01M?

2

What is the pH of a solution with a concentration of HCl of 0.001M?

3

Which of the following is an example of a strong base?

NaOH

Which of the following equations represents the ionization of NaOH in water?

NaOH + H2O -> Na+ + OH-

What is the pH of a solution with a concentration of NaOH of 0.01M?

14

What does the "p" in pH mean?

it indicates the negative logarithm of the hydrogen ion concentration

What is the Henderson-Hasselbalch equation used to describe?

The ionization of weak acids

Substance X is 50% deprotonated at a pH of 8.5 and almost 100% deprotonated at a pH of 9.5. Which of the following best describes X?

weak base

Which property of water is responsible for its high boiling point?

High heat of vaporization

What is the pH of a solution with a hydroxide ion concentration of $10^{-5}$ M?

9

A reaction has a positive ΔH. Which of the following statements is true about this reaction?

This is an endothermic reaction

What is the pH of a neutral solution?

7

Which molecule is transported back into the red blood cell in the lungs?

HCO3-

What is the role of carbonic anhydrase in the lungs?

It converts H2CO3 to CO2

What is the pH range for cell survival?

6-8

Why does blood pH increase with hyperventilation?

Hyperventilation causes a decrease in HCO3- concentration

What type of bond is stronger: a hydrogen bond or a covalent bond?

Covalent bond

What is the solute in a solution of water and salt?

Salt

What protects the body against acidity from normal metabolism?

Buffers, expiration of CO2 through the lungs, and excretion of NH4+ through the kidneys

What is the formula for calculating pH?

pH = -log[H+]

What is the range of acid production from normal metabolism in the body?

13 to 22 mol/day

Which molecule is exported in the plasma via the HCO3-/Cl- transporter?

H2CO3

How many hydrogen bonds can each water molecule form?

4

What is the main solvent in biosystems?

Water

What happens to H2CO3 in the lungs?

It is converted to water and CO2

Why do cells die when the pH falls below 6.8?

Low pH denatures enzymes

What is the main role of carbonic anhydrase in the body?

the reversible reaction of H2CO3 to CO2

What is the function of the HCO3-/Cl- transporter?

To export HCO3 from the the body and balance intracellular pH

Match the buffering system with where it works best:

Bicarbonate = An important extracellular buffer, with minimal intracellular buffering ability Phosphate = An important intracellular buffer, with minimal blood buffering ability Protein = An important intracellular buffer, with some blood buffering ability Bicarbonate = HCO3 -> H2CO3 -> carbonic anhydrase -> CO2 _ H2O

Choose the TRUE statements regarding the Henderson-Hassel Bach equation (more than one may apply):

B and C are correct

Test your knowledge on the unusual properties of water and their importance in sustaining life. Explore topics such as acids and bases, pH, and the role of water as a solvent. Discover why these properties are crucial for the existence of life as we know it.

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