The Ultimate Stem Cells Quiz

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Questions and Answers

What is the main difference between embryonic and adult stem cells?

  • Embryonic stem cells are pluripotent while adult stem cells are multipotent (correct)
  • Adult stem cells are found in embryos while embryonic stem cells are found in adult tissues
  • Adult stem cells can self-renew while embryonic stem cells cannot
  • Embryonic stem cells can differentiate into any cell type while adult stem cells can only differentiate into certain cell types

What are the two main types of stem cells?

  • Hematopoietic and Mesenchymal
  • Neuronal and Epithelial
  • Pluripotent and Multipotent
  • Embryonic and Adult (correct)

What are the two types of stem cells?

  • Adult and Fetal
  • Embryonic and Pluripotent
  • Embryonic and Fetal
  • Embryonic and Adult (correct)

What is the main difference between embryonic and adult stem cells?

<p>Embryonic stem cells are pluripotent while adult stem cells are multipotent (B)</p> Signup and view all the answers

What is plasticity in the context of adult stem cells?

<p>The ability of stem cells from one adult tissue to generate differentiated types of another tissue (A)</p> Signup and view all the answers

What is the ability of stem cells from one adult tissue to generate differentiated types of another tissue?

<p>Plasticity (B)</p> Signup and view all the answers

What are iPS cells?

<p>Induced pluripotent stem cells (C)</p> Signup and view all the answers

What is the key challenge with stem cell culture?

<p>Maintaining stem cell characteristics (C)</p> Signup and view all the answers

What is the ability of stem cells from one adult tissue to generate differentiated types of another tissue called?

<p>Plasticity (A)</p> Signup and view all the answers

What is a key challenge with stem cell culture?

<p>Maintaining the stem cells in an undifferentiated state (C)</p> Signup and view all the answers

What are the characteristics of cancer stem cells (CSCs)?

<p>Ability to give rise to new tumors, expression of stem cell transcription factors, expression of CSC cell surface markers, high expression of ABC family transporters, ability to grow as spheroids (A)</p> Signup and view all the answers

What are the three types of adult stem cells mentioned in the text?

<p>Hematopoietic, Mesenchymal, Neuronal (B)</p> Signup and view all the answers

What is the main characteristic of cancer stem cells?

<p>Ability to self-renew and generate new tumors (D)</p> Signup and view all the answers

What is the potential alternative to embryonic stem cells mentioned in the text?

<p>Individual Pluripotent Stem Cells (iPS) Cells (B)</p> Signup and view all the answers

What is the capacity of cancer stem cells to renew themselves through cell division called?

<p>Self-renewal (B)</p> Signup and view all the answers

What is the difference between cancer stem cells and regular cancer cells?

<p>Cancer stem cells have the ability to self-renew and generate new tumors, while regular cancer cells do not (A)</p> Signup and view all the answers

What is the main challenge with stem cell culture mentioned in the text?

<p>Maintaining stem cell pluripotency and preventing differentiation (C)</p> Signup and view all the answers

What is the self-renewal capacity of cancer stem cells?

<p>They are capable of renewing themselves through cell division (B)</p> Signup and view all the answers

What are some characteristics of cancer stem cells?

<p>Expression of stem cell transcription factors, expression of CSC cell surface markers, high expression of ABC family transporters (D)</p> Signup and view all the answers

What is the significance of spheroids in cancer stem cells?

<p>Spheroids express higher levels of CSC cell surface markers and have greater tumorigenic capacity (A)</p> Signup and view all the answers

What are the stem cell transcription factors expressed by cancer stem cells?

<p>OCT3/4, NANOG, SOX2 (D)</p> Signup and view all the answers

What is the role of 'stemness' factors in cancer stem cells?

<p>Critical for self-renewal in CSCs (C)</p> Signup and view all the answers

What is the ability of cancer stem cells to generate heterogeneous population of cancer cells?

<p>Ability to generate heterogeneous cancer cells (C)</p> Signup and view all the answers

What is the main characteristic of cancer stem cells that distinguishes them from other cancer cells?

<p>Ability to give rise to new tumors in serial transplants (D)</p> Signup and view all the answers

What is the relationship between cancer stem cells and the tumor microenvironment?

<p>The autonomous or tumor microenvironment can activate pathways to CSC self-renewal (B)</p> Signup and view all the answers

What is the main advantage of using spheroids in cancer stem cell research?

<p>They better mimic the in vivo tumor microenvironment (D)</p> Signup and view all the answers

What is the significance of the Hoechst33342 dye-excluding side population in cancer stem cells?

<p>More aggressive tumors have a greater number of CSCs (B)</p> Signup and view all the answers

What is the main challenge in stem cell therapy for clinical application?

<p>Ensuring the safety of the stem cells (A)</p> Signup and view all the answers

What is the main disadvantage of using chemotherapy drugs to target cancer stem cells?

<p>Spheroids are more resistant to chemotherapy drugs (B)</p> Signup and view all the answers

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