The Ultimate Quiz on Peptide Bond Formation and Translocation in Translation
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Questions and Answers

What is the function of EF-Ts in protein translation?

  • It binds to the A-site of the ribosome
  • It catalyzes translocation
  • It regenerates EF-Tu-GTP (correct)
  • It catalyzes peptide bond formation

What is the catalytic component of the ribosome responsible for peptide bond formation?

  • rRNA
  • PT ribozyme (correct)
  • Translocase
  • EF-Tu

Which subunit of the ribosome contains the PT ribozyme in bacteria?

  • 30s subunit
  • 80s subunit
  • 70s subunit
  • 50s subunit (correct)

What is the function of translocase in protein translation?

<p>It catalyzes translocation (D)</p> Signup and view all the answers

What is the role of EF-Tu in protein translation?

<p>It delivers aminoacyl-tRNA to the ribosome (A)</p> Signup and view all the answers

Which site on the ribosome does the peptidyl tRNA move to during translocation?

<p>P-site (B)</p> Signup and view all the answers

Which site on the ribosome does the free tRNA move to during translocation?

<p>E-site (D)</p> Signup and view all the answers

What is the effect of an antibiotic that inhibits translocation?

<p>It prematurely terminates translation (A)</p> Signup and view all the answers

What is the energy source for translocation during protein translation?

<p>GTP (B)</p> Signup and view all the answers

What is the function of EF-Ts in the regeneration of EF-Tu-GTP?

<p>It replaces GDP with GTP on EF-Tu (C)</p> Signup and view all the answers

What is the function of EF-Ts in protein translation?

<p>It regenerates EF-Tu-GTP (D)</p> Signup and view all the answers

What is the catalytic component of the ribosome responsible for peptide bond formation?

<p>PT ribozyme (D)</p> Signup and view all the answers

Which subunit of the ribosome contains the PT ribozyme in bacteria?

<p>50s subunit (C)</p> Signup and view all the answers

What is the function of translocase in protein translation?

<p>It catalyzes translocation (C)</p> Signup and view all the answers

What is the role of EF-Tu in protein translation?

<p>It delivers aminoacyl-tRNA to the ribosome (B)</p> Signup and view all the answers

Which site on the ribosome does the peptidyl tRNA move to during translocation?

<p>P-site (D)</p> Signup and view all the answers

Which site on the ribosome does the free tRNA move to during translocation?

<p>E-site (D)</p> Signup and view all the answers

What is the effect of an antibiotic that inhibits translocation?

<p>It prematurely terminates translation (D)</p> Signup and view all the answers

What is the energy source for translocation during protein translation?

<p>GTP (C)</p> Signup and view all the answers

What is the function of EF-Ts in the regeneration of EF-Tu-GTP?

<p>It replaces GDP with GTP on EF-Tu (C)</p> Signup and view all the answers

What is the function of EF-Ts?

<p>It regenerates EF-Tu-GTP (A)</p> Signup and view all the answers

Which site is responsible for peptide bond formation?

<p>A-site (C)</p> Signup and view all the answers

What is the function of peptidyl transferase (PT)?

<p>It catalyzes peptide bond formation (C)</p> Signup and view all the answers

What is the ribozyme responsible for catalyzing peptide bond formation in bacteria?

<p>23s rRNA of 50s subunit (C)</p> Signup and view all the answers

What is the ribozyme responsible for catalyzing peptide bond formation in eukaryotes?

<p>28s rRNA in 60s subunit (C)</p> Signup and view all the answers

What is the function of translocase?

<p>It catalyzes translocation (C)</p> Signup and view all the answers

Which tRNA site is responsible for holding the growing polypeptide chain?

<p>P-site (B)</p> Signup and view all the answers

Which tRNA site is responsible for holding the next amino acid to be added to the polypeptide chain?

<p>A-site (B)</p> Signup and view all the answers

What happens to the free tRNA after translocation?

<p>It moves to the 'E-site' and exits (B)</p> Signup and view all the answers

What is the consequence of an antibiotic inhibiting translocation?

<p>It inhibits EF-Ts (C)</p> Signup and view all the answers

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