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Questions and Answers
Which family of viruses is responsible for causing gastroenteritis?
Which family of viruses is responsible for causing gastroenteritis?
- Flaviviridae
- Reoviridae (correct)
- Orthomyxoviridae
- Filoviridae
Which component of the virus is important for the replication cycle?
Which component of the virus is important for the replication cycle?
- VP1 and VP2
- VP3 and VP4
- VP4 and VP7 (correct)
- VP5 and VP6
Which group of rotaviruses is responsible for causing human diseases?
Which group of rotaviruses is responsible for causing human diseases?
- Group A (correct)
- Group B
- Group C
- Group D
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Study Notes
- Gastroenteritis is caused by naked icosahedral viruses.
- They are classified into RNA viruses (Reoviridae family) and double-stranded DNA viruses (Adenoviridae family).
- Rotaviruses are wheel-shaped with a protein capsid made of three layers.
- They have 11 segments of double-stranded RNA and are divided into seven groups.
- Human diseases are mostly caused by group A viruses.
- The replication cycle involves endocytosis, synthesis of proteins, and reconstitution of dsRNA.
- Caliciviridae, Astroviridae, and Picornaviridae are ss-RNA viruses also responsible for gastroenteritis.
- VP4 and VP7 are important components of the virus.
- The virion loses its layers during replication, changing from TLP to DLP to SLP.
- The virus leaves the cell through lysis.
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