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Questions and Answers
What is immunocompetence?
What is immunocompetence?
- The prevention of autoimmune diseases
- The process of lymphocyte specialization for reacting to only one specific antigen
- The ability of the body to react with countless foreign substances (correct)
- The rapid mobilization of lymphocytes that have been programmed to recall their first engagement with the invader
Where do B cells mature?
Where do B cells mature?
- Spleen
- Thymus
- Bone marrow (correct)
- Lymphoid tissues
What is the function of an antigen presenting cell (APC)?
What is the function of an antigen presenting cell (APC)?
- To rapidly mobilize lymphocytes
- To present antigens to T cells (correct)
- To prevent autoimmune diseases
- To produce clones of activated lymphocytes
What is the result of mitosis after lymphocyte activation?
What is the result of mitosis after lymphocyte activation?
Where do T cells migrate to for further development?
Where do T cells migrate to for further development?
What is the role of B and T cells upon reaching secondary lymphoid tissues?
What is the role of B and T cells upon reaching secondary lymphoid tissues?
What is the key feature of each naïve lymphocyte?
What is the key feature of each naïve lymphocyte?
What is the characteristic of specific immunity with respect to antigen recognition?
What is the characteristic of specific immunity with respect to antigen recognition?
What is the process that specializes lymphocytes for reacting to only one specific antigen?
What is the process that specializes lymphocytes for reacting to only one specific antigen?
Which type of T cell is responsible for preventing autoimmunity?
Which type of T cell is responsible for preventing autoimmunity?
What is the function of specific immunity in the context of autoimmune diseases?
What is the function of specific immunity in the context of autoimmune diseases?
Which antibody class is present in secretions from mucous membranes?
Which antibody class is present in secretions from mucous membranes?
What is the function of IgE antibody?
What is the function of IgE antibody?
What is the biological function of IgG antibody?
What is the biological function of IgG antibody?
What is the function of perforins in cytotoxic T cell activation?
What is the function of perforins in cytotoxic T cell activation?
What is the primary function of B cells when activated by antigen?
What is the primary function of B cells when activated by antigen?
What is the main function of memory T cells?
What is the main function of memory T cells?
What is the role of IgM antibody in the immune response?
What is the role of IgM antibody in the immune response?
What is the function of killer T cells (CD8 cells)?
What is the function of killer T cells (CD8 cells)?
What is the purpose of monitoring antibody production over time?
What is the purpose of monitoring antibody production over time?
What is the function of B-cells in the immune system?
What is the function of B-cells in the immune system?
What are the components of immunoglobulins (antibodies)?
What are the components of immunoglobulins (antibodies)?
What leads to antibody variability?
What leads to antibody variability?
How do T cell receptors differ from B cell receptors?
How do T cell receptors differ from B cell receptors?
What types of molecules do B cell receptors recognize?
What types of molecules do B cell receptors recognize?
What is the function of clonal deletion in the immune system?
What is the function of clonal deletion in the immune system?
What are antigens in the context of the immune system?
What are antigens in the context of the immune system?
What are alloantigens in the context of the immune system?
What are alloantigens in the context of the immune system?
What are epitopes in the context of the immune system?
What are epitopes in the context of the immune system?
What is the function of the Major Histocompatibility Complex (MHC) in the immune system?
What is the function of the Major Histocompatibility Complex (MHC) in the immune system?
Study Notes
Understanding the Immune System
- B-cells "home" to lymphoid tissue and produce immunoglobulins, which are antibodies.
- Immunoglobulins have constant and variable regions, and a Y-shaped arrangement with two binding sites.
- The gene for the binding region has interchangeable sections, leading to antibody variability.
- T cell receptors are similar to B cell receptors but are smaller and never secreted.
- B cell receptors recognize many types of molecules, while T cell receptors recognize only proteins.
- Clonal deletion removes potentially harmful clones, forming the basis of immune tolerance.
- Antigens are chemical substances that bind to immune cells and can be immunogens or haptens.
- Epitopes are the portion of the antigen molecule recognized by lymphocytes, signaling foreignness.
- Alloantigens are cell surface markers that occur in some members of the same species but not in others.
- Superantigens are potent stimuli for T cells, activating them at a rate 100 times greater than ordinary antigens.
- The Major Histocompatibility Complex (MHC) codes for cell surface proteins and presents antigens to T cells.
- Antigen presenting cells, such as dendritic cells, macrophages, and B cells, present antigens to T-lymphocytes.
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Description
Test your knowledge of the immune system with this quiz covering B-cells, T-cells, antibodies, antigens, MHC, and more. Challenge yourself with questions on immune tolerance, clonal deletion, and the role of antigen presenting cells.
