The T Cell Connection
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Questions and Answers

Which of the following is NOT a major cause of T cell-mediated hypersensitivity reactions?

  • Excessive polyclonal T cell activation
  • Autoimmunity
  • Exaggerated responses to microbial antigens
  • Inhibition of T cell recruitment (correct)
  • Which of the following is true about T cell-mediated autoimmune diseases?

  • They are not systemic
  • They are not limited to a few organs (correct)
  • They usually affect multiple organs
  • They are directed against cellular antigens with widespread tissue distribution
  • What is the role of superantigens in T cell activation?

  • They inhibit T cell activation
  • They activate T cells regardless of antigen specificity (correct)
  • They bind to specific antigens on T cell receptors
  • They stimulate a small number of T cell clones
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