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10 Questions

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The Origins of Chromosomal Aberrations

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Questions and Answers

Which of the following is a cause of chromosomal aberrations?

Errors in somatic DNA repair mechanism

Errors in meiosis

Errors in mitosis

All of the above (correct)

Which template(s) do DNA repair mechanisms use for base pairing/polymerization or end joining after trimming?

Opposite strand

Sister chromatid

Homologous chromosome

All of the above (correct)

What can result from error/mutations in the proteins involved in cell reductive division, DNA duplication, and DNA repair?

Chromosomal aberrations

Mutations (correct)

CRISPer-based gene repair

All of the above

What is the goal of CRISPer-based gene repair?

To repair genes Signup and view all the answers

Why is CRISPer currently not very efficient at gene repair?

Due to our poor understanding of DNA repair mechanisms Signup and view all the answers

Which of the following is NOT a cause of chromosomal aberrations?

Errors in DNA duplication Signup and view all the answers

Which of the following is true about DNA repair mechanisms?

They use either the opposite strand, sister chromatid, or homologous chromosome as a template for base pairing/polymerization or end joining after trimming Signup and view all the answers

What is the main goal of CRISPer-based gene repair?

To develop efficient gene repair techniques Signup and view all the answers

What is the current limitation of CRISPer-based gene repair?

Lack of understanding of DNA repair mechanisms Signup and view all the answers

What is a highly regulated form of DNA damage followed by homologous recombination as the repair mechanism?

Meiosis Signup and view all the answers