The Origins of Chromosomal Aberrations
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Questions and Answers

Which of the following is a cause of chromosomal aberrations?

  • Errors in somatic DNA repair mechanism
  • Errors in meiosis
  • Errors in mitosis
  • All of the above (correct)

Which template(s) do DNA repair mechanisms use for base pairing/polymerization or end joining after trimming?

  • Opposite strand
  • Sister chromatid
  • Homologous chromosome
  • All of the above (correct)

What can result from error/mutations in the proteins involved in cell reductive division, DNA duplication, and DNA repair?

  • Chromosomal aberrations
  • Mutations (correct)
  • CRISPer-based gene repair
  • All of the above

What is the goal of CRISPer-based gene repair?

<p>To repair genes (C)</p> Signup and view all the answers

Why is CRISPer currently not very efficient at gene repair?

<p>Due to our poor understanding of DNA repair mechanisms (A)</p> Signup and view all the answers

Which of the following is NOT a cause of chromosomal aberrations?

<p>Errors in DNA duplication (A)</p> Signup and view all the answers

Which of the following is true about DNA repair mechanisms?

<p>They use either the opposite strand, sister chromatid, or homologous chromosome as a template for base pairing/polymerization or end joining after trimming (D)</p> Signup and view all the answers

What is the main goal of CRISPer-based gene repair?

<p>To develop efficient gene repair techniques (D)</p> Signup and view all the answers

What is the current limitation of CRISPer-based gene repair?

<p>Lack of understanding of DNA repair mechanisms (D)</p> Signup and view all the answers

What is a highly regulated form of DNA damage followed by homologous recombination as the repair mechanism?

<p>Meiosis (A)</p> Signup and view all the answers

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