10 Questions
Which of the following is a cause of chromosomal aberrations?
All of the above
Which template(s) do DNA repair mechanisms use for base pairing/polymerization or end joining after trimming?
All of the above
What can result from error/mutations in the proteins involved in cell reductive division, DNA duplication, and DNA repair?
Mutations
What is the goal of CRISPer-based gene repair?
To repair genes
Why is CRISPer currently not very efficient at gene repair?
Due to our poor understanding of DNA repair mechanisms
Which of the following is NOT a cause of chromosomal aberrations?
Errors in DNA duplication
Which of the following is true about DNA repair mechanisms?
They use either the opposite strand, sister chromatid, or homologous chromosome as a template for base pairing/polymerization or end joining after trimming
What is the main goal of CRISPer-based gene repair?
To develop efficient gene repair techniques
What is the current limitation of CRISPer-based gene repair?
Lack of understanding of DNA repair mechanisms
What is a highly regulated form of DNA damage followed by homologous recombination as the repair mechanism?
Meiosis
Test your knowledge on the origins of chromosomal aberrations and how they occur. Explore the role of DNA repair mechanisms, meiosis, and mitosis in causing these genetic variations.
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