The Glycolytic Energy System Quiz
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Questions and Answers

What are the potential consequences of inadequate glucose supply for the CNS?

Hypoglycaemia, weakness, hunger, dizziness, loss of consciousness, coma or irreversible brain damage

What is the optimal glucose solution concentration for CHO drinks?

5 to 8%

What is the typical daily carbohydrate intake for athletes?

Amount depends on frequency, duration and intensity of the exercise, but training athletes should aim for 60% and intense training athletes should aim for 70%

What are the three ATP synthesis pathways?

<ol> <li>ATP-PCr system (anaerobic) 2. Glycolytic system (anaerobic) 3. Oxidative system (aerobic)</li> </ol> Signup and view all the answers

What is the literal meaning of glycolysis?

<p>To split sugar</p> Signup and view all the answers

What are the two main transporters for glucose and where are they found?

<p>GLUT 2 Transporters - Liver, Pancreas, Renal tubules. GLUT 4 Transporters - Skeletal muscle and adipose tissue.</p> Signup and view all the answers

What is the net gain of ATP in glycolysis when glucose is converted to pyruvate from glycogen?

<p>3 ATP</p> Signup and view all the answers

What is the purpose of ATP in step 1 of glycolysis?

<p>To phosphorylate glucose into glucose 6-phosphate, keeping glucose in the cell and priming the process of glycolysis.</p> Signup and view all the answers

What are the two 3-C molecules produced in step 4 and step 5 of glycolysis?

<p>Dihydroxyacetone phosphate (DHAP) and 3-phosphoglyceraldehyde.</p> Signup and view all the answers

What is the fate of pyruvate in low-moderate energy demand?

<p>It continues to Stage 2, Krebs cycle, which requires O2 and oxidative phosphorylation.</p> Signup and view all the answers

How many net ATP molecules are produced from the breakdown of glucose and glycogen in glycolysis?

<p>2 ATP for glucose and 3 ATP for glycogen.</p> Signup and view all the answers

What is the role of carbohydrate in exercise performance?

<p>Carbohydrate is important for providing energy during exercise, specifically during endurance events. It also affects gastric emptying and can impact performance.</p> Signup and view all the answers

What is glycolysis?

<p>Glycolysis is the process of breaking down glucose to produce ATP, which is used for energy in the body.</p> Signup and view all the answers

What are the different types of muscle fibers and their characteristics?

<p>There are several types of muscle fibers including slow-twitch oxidative, fast-twitch oxidative glycolytic, and glycolytic fibers. They differ in their energy systems and abilities to generate force and endurance.</p> Signup and view all the answers

What are the three types of carbohydrates and how do they differ?

<p>The three types of carbohydrates are polysaccharides (10+ sugars), oligosaccharides (3-9 sugars), and monosaccharides (1 sugar). They differ in their chemical structure and how they are broken down and used in the body.</p> Signup and view all the answers

What is glycogenesis and how does it contribute to carbohydrate storage?

<p>Glycogenesis is the process of converting excess blood glucose to glycogen for storage in the liver or muscle.</p> Signup and view all the answers

What is the average amount of energy stored by the human body in the form of glycogen?

<p>The average person stores around 8400 kJ (500 g x 17 kJ) of energy in the form of glycogen.</p> Signup and view all the answers

What is glycogenolysis and how does it contribute to energy production during exercise?

<p>Glycogenolysis is the process of converting glycogen to glucose for eventual use as energy. The glucose is then transferred to muscles via the blood.</p> Signup and view all the answers

What is 'hitting the wall' and why does it occur during endurance exercise?

<p>'Hitting the wall' is a phenomenon linked to glycogen depletion during endurance exercise, commonly reported by marathon runners after about 35km. When glycogen stores are exhausted, performance is affected, and symptoms such as tingling, numbness, confusion, and a significant decrease in pace can occur.</p> Signup and view all the answers

What is the role of PFK in response to high energy demand?

<p>PFK 'senses' increased energy demand and increases glycolysis rate.</p> Signup and view all the answers

What are the electron carriers involved in the glycolytic energy system?

<p>NAD+ and FAD.</p> Signup and view all the answers

What is the fate of lactate and H+ once they leave the cell?

<p>They are transported via lactate transport proteins and can be buffered or enter the Cori cycle for gluconeogenesis.</p> Signup and view all the answers

What is the OIL RIG principle and how does it relate to NAD+ and NADH?

<p>OIL RIG (Oxidation is Loss, Reduction is Gain) explains the transfer of electrons from NAD+ to NADH, where NAD+ is reduced by gaining an electron and a whole hydrogen atom (proton and electron) attaches to NAD to form NADH.</p> Signup and view all the answers

What are buffering systems and how do they maintain pH within tolerable limits?

<p>Buffering systems are chemical and physical mechanisms that help maintain pH within tolerable limits by neutralizing acidic/alkaline conditions. Chemical buffers restore pH within a fraction of a second, while physical buffers assist chemical buffers and provide long-term control.</p> Signup and view all the answers

What is the Bicarbonate buffering system and how does it work?

<p>The Bicarbonate buffering system is a chemical buffer that neutralizes excess H+ ions in the blood by converting them into H2CO3 (carbonic acid), which then breaks down into CO2 and H2O. This helps maintain pH within tolerable limits.</p> Signup and view all the answers

What is the significance of blood lactate measurement during exercise and what are the usual levels of blood lactate at rest and during maximal exercise?

<p>Blood lactate measurement during exercise is significant because it indicates the intensity of exercise and the body's ability to clear lactate. The usual levels of blood lactate at rest are 1-2 mmol·L-1, while maximal exercise can produce levels of ~20-22 mmol·L-1.</p> Signup and view all the answers

Study Notes

Consequences of Inadequate Glucose Supply

  • Inadequate glucose supply to the central nervous system (CNS) can lead to impaired cognitive function, dizziness, and even loss of consciousness.

Optimal Glucose Solution Concentration

  • The optimal glucose solution concentration for carbohydrate (CHO) drinks is 6-8%, which is isotonic with blood plasma.

Daily Carbohydrate Intake for Athletes

  • The typical daily carbohydrate intake for athletes is 2-3 grams per kilogram of body weight.

ATP Synthesis Pathways

  • There are three ATP synthesis pathways: ATP-PC system, glycolytic system, and oxidative system.

Meaning of Glycolysis

  • The literal meaning of glycolysis is "glucose breaking" or "sugar splitting".

Glucose Transporters

  • The two main transporters for glucose are GLUT1 and GLUT4, found in the blood-brain barrier and muscles, respectively.

Net ATP Gain in Glycolysis

  • The net gain of ATP in glycolysis when glucose is converted to pyruvate from glycogen is 3 ATP.

Purpose of ATP in Glycolysis

  • The purpose of ATP in step 1 of glycolysis is to phosphorylate glucose, trapping it in the cell.

3-C Molecules Produced in Glycolysis

  • The two 3-C molecules produced in step 4 and step 5 of glycolysis are glyceraldehyde-3-phosphate and dihydroxyacetone phosphate.

Fate of Pyruvate in Low-Moderate Energy Demand

  • In low-moderate energy demand, pyruvate is converted to lactate, and then lactate is transported out of the muscle cell.

Net ATP Molecules Produced in Glycolysis

  • 2 net ATP molecules are produced from the breakdown of glucose and glycogen in glycolysis.

Role of Carbohydrate in Exercise Performance

  • Carbohydrate plays a crucial role in exercise performance, providing energy for the body during exercise.

Definition of Glycolysis

  • Glycolysis is the metabolism of glucose to pyruvate, producing ATP and NADH.

Types of Muscle Fibers and Characteristics

  • There are three types of muscle fibers: slow-twitch (Type I), fast-twitch (Type II), and intermediate (Type IIa).

Types of Carbohydrates and Differences

  • The three types of carbohydrates are simple sugars (monosaccharides), complex sugars (disaccharides and polysaccharides), and fiber.

Glycogenesis and Carbohydrate Storage

  • Glycogenesis is the process of converting glucose into glycogen for storage in the liver and muscles.

Average Energy Stored as Glycogen

  • The average amount of energy stored by the human body in the form of glycogen is approximately 1500-2000 kcal.

Glycogenolysis and Energy Production

  • Glycogenolysis is the breakdown of glycogen to glucose, contributing to energy production during exercise.

'Hitting the Wall' during Endurance Exercise

  • 'Hitting the wall' is a phenomenon that occurs during endurance exercise when glycogen stores are depleted, leading to fatigue.

Role of PFK in High Energy Demand

  • Phosphofructokinase (PFK) plays a crucial role in response to high energy demand, regulating glycolytic flux.

Electron Carriers in the Glycolytic Energy System

  • The electron carriers involved in the glycolytic energy system are NAD+ and FAD+.

Fate of Lactate and H+ after Leaving the Cell

  • Lactate and H+ are transported out of the muscle cell and into the bloodstream, where they can be taken up by the liver for gluconeogenesis.

OIL RIG Principle

  • The OIL RIG principle stands for "Oxidation Is Loss of electron, Reduction Is Gain of electron", relating to NAD+ and NADH.

Buffering Systems and pH Maintenance

  • Buffering systems, such as the bicarbonate buffering system, help maintain pH within tolerable limits by neutralizing excess H+ ions.

Bicarbonate Buffering System

  • The bicarbonate buffering system involves the equilibrium reaction between bicarbonate and carbonic acid, maintaining pH homeostasis.

Blood Lactate Measurement during Exercise

  • Blood lactate measurement during exercise is significant, as it indicates anaerobic energy production and muscle fatigue. Usual levels of blood lactate are 1-2 mmol/L at rest and 8-12 mmol/L during maximal exercise.

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Description

Test your knowledge on the glycolytic energy system and its role in meeting high energy demands. This quiz covers the steps involved in glycolysis, the enzymes and molecules involved, and the importance of this system in energy production. Keywords: high energy demand, glycolysis, enzymes, molecules, energy production.

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