The Complement System

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Questions and Answers

Which of the following best describes the role of the complement system in host defense against microbes?

  • The complement system inhibits the activation of antibodies.
  • The complement system assists antibodies in destroying cells. (correct)
  • The complement system directly destroys microbes.
  • The complement system activates the innate immune response.

How is the complement system activated?

  • Both by microbes in the absence of antibody and by antibodies attached to microbes. (correct)
  • Only in the absence of antibody as part of the innate immune response.
  • Only by antibodies attached to microbes.
  • Only by microbes in the absence of antibody.

What prevents complement-mediated damage to healthy cells?

  • The activation of complement proteins.
  • The generation of effector molecules.
  • The deposition of activated complement proteins.
  • The regulatory mechanisms of normal host cells. (correct)

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