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Questions and Answers
Who first proposed the 'Central Dogma' of molecular biology and when?
Francis Crick proposed the 'Central Dogma' in 1958.
What is the central dogma of molecular biology and what does it explain?
The central dogma explains the flow of genetic information, from DNA to RNA, to make a functional product, a protein.
What role does RNA play in the central dogma of molecular biology?
RNA is a messenger that carries the information from DNA to the ribosomes, where it is 'translated' into a functional product.
What are the two key stages of gene expression according to the central dogma?
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What happens during transcription and translation in the process of gene expression?
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Study Notes
Central Dogma of Molecular Biology
- Francis Crick first proposed the 'Central Dogma' of molecular biology in the 1950s.
- The central dogma explains the flow of genetic information from DNA to proteins, involving the sequential processes of transcription and translation.
Role of RNA
- RNA (Ribonucleic acid) plays a crucial role in the central dogma as a messenger molecule, carrying genetic information from DNA to the ribosomes.
Gene Expression
- The two key stages of gene expression according to the central dogma are transcription and translation.
- Transcription is the process of creating a complementary RNA copy from a DNA template, while translation is the process of building a polypeptide chain from the RNA sequence.
Transcription and Translation
- During transcription, the enzyme RNA polymerase reads the DNA template and adds nucleotides to a growing RNA chain, forming a primary transcript.
- During translation, the RNA sequence is read by ribosomes, which build a polypeptide chain by adding amino acids corresponding to the RNA codons.
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Description
Test your knowledge of the central dogma of molecular biology with this informative quiz. Explore the flow of genetic information from DNA to RNA and protein synthesis as proposed by Francis Crick in 1958. See how well you understand this fundamental concept in molecular biology.
