The Arthus Reaction and Type IV Hypersensitivity Quiz
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Questions and Answers

Which type of adverse drug reaction is characterized by chronic effects after long use of drugs?

  • Type D
  • Type C (correct)
  • Type B
  • Type A

    • What is the term used to describe unavoidable undesirable normal actions produced by therapeutic dose of a drug?

  • Secondary Effect
  • Super-sensitivity
  • Over-dose
  • Side Effect (correct)

    • Which type of adverse drug reaction is characterized by an abnormal unpredictable reaction usually due to an antigen/antibody reaction?

  • Type II
  • Type III
  • Type I (correct)
  • Type IV

    • Which of the following is NOT a pattern of adverse drug reactions (ADR) according to the ABCDE Classification?

    <p>Bizzar</p> Signup and view all the answers

    What is the difference between tolerance and desensitization (Tachyphylaxis)?

    <p>Tolerance is the complete loss of response to a drug, while desensitization is the decreased response to a drug over time</p> Signup and view all the answers

    What is the clinical principle regarding drug effects?

    <p>Drugs should have minimum side effects</p> Signup and view all the answers

    Which type of hypersensitivity reaction is characterized by the involvement of T-lymphocytes and inflammation?

    <p>Type IV</p> Signup and view all the answers

    What is the main difference between allergy and idiosyncrasy?

    <p>Allergy is an abnormal response due to genetic abnormality, while idiosyncrasy is an unpredictable abnormal response due to genetic abnormality.</p> Signup and view all the answers

    What are the characteristics of acquired tolerance?

    <p>Reversal of drug effects with time, varies from one drug to another, does not affect all actions to the same extent</p> Signup and view all the answers

    Which of the following best describes primary failure in the treatment of Type I diabetes mellitus?

    <p>Failure of insulin treatment due to occurrence of tolerance</p> Signup and view all the answers

    What is the term used to describe a more gradual loss of response to a drug that occurs over days or weeks due to repeated administration?

    <p>Pharmacodynamic tolerance</p> Signup and view all the answers

    What is the term used to describe a sudden loss of response to a drug?

    <p>Tachyphylaxis</p> Signup and view all the answers

    Which of the following is NOT a mechanism of tachyphylaxis?

    <p>Increased metabolic degradation</p> Signup and view all the answers

    What does desensitization refer to?

    <p>Signal attenuation in response to continuous stimulation of cells by receptor agonists</p> Signup and view all the answers

    What is secondary failure in the treatment of Type I diabetes mellitus?

    <p>Failure of insulin treatment due to a more rapid loss of response</p> Signup and view all the answers

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