Tetracyclines Mechanism of Action

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Questions and Answers

How do tetracyclines penetrate the cell wall?

  • Through ATP-dependent active transport system only
  • Through passive diffusion only
  • By both passive diffusion and ATP-dependent active transport system (correct)
  • Through enzymatic inactivation

What is the range of absorption for tetracycline and oxytetracycline?

  • 95-100%
  • 40-60%
  • 60-70% (correct)
  • 80-90%

What is the mechanism of resistance of tetracyclines in bacteria?

  • Impaired diffusion and enzymatic inactivation (correct)
  • Impaired diffusion only
  • Enzymatic inactivation only
  • Bacteria protein synthesis

What is a common adverse effect of tetracyclines in children under 12 years old?

<p>All of the above (D)</p>
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What is the mechanism of action of tetracyclines on protein synthesis?

<p>They bind reversibly to the 30S ribosomal subunit (B)</p>
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