Podcast
Questions and Answers
What is the significance of biological systems being highly complex?
What is the significance of biological systems being highly complex?
- It makes in vitro and in vivo testing unnecessary
- It simplifies the mechanistic understanding of systems
- It requires virtual exploration of many scenarios to understand (correct)
- It allows for easy development of therapies and devices
What is the purpose of discretizing the geometry in Computational Fluid Dynamics?
What is the purpose of discretizing the geometry in Computational Fluid Dynamics?
- To eliminate the need for virtual exploration
- To make the system less complex
- To model flow physics (correct)
- To simplify the regulatory pipeline for medical devices
Why is it impossible to understand biological systems without computers?
Why is it impossible to understand biological systems without computers?
- Because biological systems are highly complex (correct)
- Because the regulatory pipeline for medical devices is too complex
- Because therapies and devices cannot be developed without computers
- Because in vitro and in vivo testing are not effective
What does ISO 10993 specify?
What does ISO 10993 specify?
What is the main focus of testing according to the text?
What is the main focus of testing according to the text?
What is the purpose of biocompatibility testing?
What is the purpose of biocompatibility testing?
Which organization participates as a member in ISO?
Which organization participates as a member in ISO?
What does ISO 14708 specify?
What does ISO 14708 specify?
What is the definition of biocompatibility according to the given text?
What is the definition of biocompatibility according to the given text?
What is the main purpose of hemocompatibility testing?
What is the main purpose of hemocompatibility testing?
What is thrombogenesis primarily associated with in hemocompatibility testing?
What is thrombogenesis primarily associated with in hemocompatibility testing?
In the context of in-vitro thrombogenicity testing, what does Virchow triad refer to?
In the context of in-vitro thrombogenicity testing, what does Virchow triad refer to?
What are the limitations of pressure testing in in-vitro thrombogenicity?
What are the limitations of pressure testing in in-vitro thrombogenicity?
What is the '3R' principle mentioned in the context of in-vivo hemocompatibility testing?
What is the '3R' principle mentioned in the context of in-vivo hemocompatibility testing?
What is the primary reason for using mock circulation loops in testing?
What is the primary reason for using mock circulation loops in testing?
What do numerical simulations specifically calculate in the context of testing?
What do numerical simulations specifically calculate in the context of testing?
What are the specific biological characteristics assessed in a centrifugal blood pump during testing?
What are the specific biological characteristics assessed in a centrifugal blood pump during testing?
What does the HQ curve primarily illustrate in relation to a blood pump?
What does the HQ curve primarily illustrate in relation to a blood pump?
What does NIH stand for in the context of hemolysis testing?
What does NIH stand for in the context of hemolysis testing?
Why is modeling important in medical device testing?
Why is modeling important in medical device testing?
What does PIV visualization primarily help with during testing?
What does PIV visualization primarily help with during testing?
