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Questions and Answers
What is the primary nitrogenous waste excreted daily by the kidneys?
What is the primary nitrogenous waste excreted daily by the kidneys?
- Creatinine
- Urea (correct)
- Uric acid
- Ammonia
What percentage of urea is reabsorbed in the collecting ducts during water reabsorption?
What percentage of urea is reabsorbed in the collecting ducts during water reabsorption?
- 60-80%
- 40-60% (correct)
- 20-30%
- 10-20%
What is the impact of elevated ammonia in the bloodstream?
What is the impact of elevated ammonia in the bloodstream?
- It can affect the central nervous system (correct)
- It can increase urine flow rate
- It can lead to renal disease
- It can cause uremia
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Study Notes
- Laboratory methods for renal function rely on measuring urea, creatinine, and uric acid in the blood.
- Urea is formed from the breakdown of amino acids and is excreted by the kidneys.
- Urea makes up the majority of nitrogenous waste excreted daily.
- 40-60% of urea is reabsorbed in the collecting ducts during water reabsorption.
- Urea contributes to high osmolality in the medulla.
- Urea back-diffusion depends on urine flow rate.
- Kidney disease leads to urea accumulation in the blood, causing uremia or uremic syndrome.
- Elevated ammonia in the bloodstream can impact the CNS.
- Urea measurements can aid in evaluating renal function, assessing hydration status, diagnosing renal disease, or verifying dialysis adequacy.
- Dialysis or transplantation is necessary to treat uremia.
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