Test Your Knowledge on Therapeutic Drug Monitoring (TDM)
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Questions and Answers

What is therapeutic drug monitoring (TDM)?

  • The use of drug concentration measurements in body fluids as an aid to the management of drug therapy for the cure, alleviation or prevention of disease (correct)
  • The use of drug concentration measurements in body fluids to cure diseases
  • The use of drug concentration measurements in body fluids to alleviate diseases
  • The use of drug concentration measurements in body fluids to prevent diseases
  • When is monitoring unnecessary?

  • When there is a narrow margin between the toxic dose and the therapeutically effective dose
  • When the drug's action can be easily assessed clinically
  • When the drug's action cannot be easily assessed clinically
  • When there is a wide margin between the toxic dose and the therapeutically effective dose (correct)
  • When was therapeutic drug monitoring (TDM) routinely practiced in clinical laboratories?

  • In the late 1970s
  • In the mid-1960s
  • In the early 1980s
  • In the early 1970s (correct)
  • What is the process of therapeutic drug monitoring (TDM)?

    <p>It begins with a clinical question, devises a sampling strategy, determines one or more drug or metabolite concentrations, and interprets the results appropriately</p> Signup and view all the answers

    What led to the surge of publications in the early 1970s on improving individualization of therapy by the monitoring of drug concentration and appropriate adjustment of dose?

    <p>The relationship between plasma concentration and pharmacological effect for lithium demonstrated by Baastrup and Schou in 1967</p> Signup and view all the answers

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