Podcast
Questions and Answers
What is the role of snRNPs in splicing?
What is the role of snRNPs in splicing?
- They stabilize mRNA
- They degrade introns
- They form a spliceosome (correct)
- They bind to exons
What is the consequence of homozygous mutations in the 5' or 3' intronic splice site?
What is the consequence of homozygous mutations in the 5' or 3' intronic splice site?
- mRNA is translated incorrectly
- mRNA cannot leave the nucleus and is degraded (correct)
- mRNA can leave the nucleus but is degraded
- mRNA is translated normally
What type of bond is formed between the branch site A and the splice donor site of the intron during splicing?
What type of bond is formed between the branch site A and the splice donor site of the intron during splicing?
- 3'-->5' phosphodiester bond
- 2'-->5' phosphodiester bond (correct)
- 5'-->3' phosphodiester bond
- 5'-->5' phosphodiester bond
What attacks the 5'-p at the acceptor site during splicing?
What attacks the 5'-p at the acceptor site during splicing?
What is the consequence of the presence of introns in mRNA?
What is the consequence of the presence of introns in mRNA?