50 Questions
What is sexual differentiation?
The process of becoming male or female during embryonic development.
What is sexual differentiation?
The process of becoming male or female during embryonic development.
What is sexual determination?
A molecular switch that determines the pathway an embryo will take
What is sexual differentiation?
The process of becoming male or female during embryonic development.
What is sexual determination?
A molecular switch that determines the pathway an embryo will take
What is sexual determination?
A molecular switch that determines the pathway an embryo will take
What is gonadal sex?
The first thing that develops to identify whether the fetus is male or female
What is sexual determination?
The process of becoming male or female during embryonic development.
What is gonadal sex?
The first thing that develops to identify whether the fetus is male or female
What is sexual determination?
A molecular switch that determines the pathway an embryo will take
Which gene determines gonadal sex?
SRY gene on the Y chromosome
What is gonadal sex?
The first thing that develops to identify whether the fetus is male or female
Which gene determines gonadal sex?
SRY gene on the Y chromosome
What is gonadal sex?
The first thing that develops to identify whether the fetus is male or female
What is gonadal sex?
The first thing that develops to identify whether the fetus is male or female
What determines gonadal sex?
The SRY gene on the Y chromosome
What is the role of 5α-reductase in sexual differentiation?
It converts testosterone to DHT, which causes differentiation of the male external genitalia
What determines gonadal sex?
The SRY gene on the Y chromosome
What is the role of 5α-reductase in sexual differentiation?
It converts testosterone to DHT, which causes differentiation of the male external genitalia
What determines gonadal sex?
The SRY gene on the Y chromosome
What are the disorders of sexual differentiation?
Gonadal dysgenesis and sex reversal
What influences the development of internal and external genitalia?
The products of the pair of gonads.
What influences the development of internal and external genitalia?
The products of the pair of gonads.
What are the disorders of sexual differentiation?
Gonadal dysgenesis and sex reversal
What influences the development of internal and external genitalia?
The products of the pair of gonads.
What enzyme converts testosterone to DHT?
5α-reductase
What is Androgen Insensitivity Syndrome (AIS)?
When a patient is XY and makes testosterone, but it has no effect
What is Androgen Insensitivity Syndrome (AIS)?
When a patient is XY and makes testosterone, but it has no effect
What is the role of 5α-reductase in sexual differentiation?
It converts testosterone to DHT, which causes differentiation of the male external genitalia
What is the enzyme that converts testosterone to DHT?
5α-reductase
What is the cause of salt wasting in congenital adrenal hyperplasia?
Lack of aldosterone
What are some disorders of sexual differentiation?
Gonadal dysgenesis, sex reversal, and intersex.
What are some disorders of sexual differentiation?
Gonadal dysgenesis, sex reversal, and intersex.
What is the cause of salt wasting in congenital adrenal hyperplasia?
Lack of aldosterone
What are some disorders of sexual differentiation?
Gonadal dysgenesis, sex reversal, and intersex.
What is Androgen Insensitivity Syndrome (AIS)?
A condition where a patient is XY and makes testosterone, but it has no effect.
What is the treatment for congenital adrenal hyperplasia?
Glucocorticoid treatment
What is Androgen Insensitivity Syndrome (AIS)?
When a patient is XY and makes testosterone, but it has no effect.
What is the treatment for congenital adrenal hyperplasia?
Glucocorticoid treatment
What is Androgen Insensitivity Syndrome (AIS)?
A condition where a patient is XY and makes testosterone, but it has no effect.
What is the current treatment for partial AIS?
No treatment is necessary
What is Turner's syndrome?
A genetic disorder that results in female external genitalia
What is the current treatment for partial AIS?
No treatment is necessary
What is the treatment for congenital adrenal hyperplasia?
Glucocorticoid treatment.
What is the treatment option for partial AIS?
Surgery is now optional for partial AIS treatment.
Is surgery necessary for partial AIS treatment?
No, it is now optional.
What is Turner's syndrome?
A genetic disorder that results in female external genitalia
What is Turner's syndrome?
A genetic disorder that results in female external genitalia
What is Turner's syndrome?
A genetic disorder that results in female external genitalia
What can congenital adrenal hyperplasia cause?
Both male and female internal genitalia
Study Notes
- Sexual differentiation is the process of becoming male or female during embryonic development.
- Sexual determination is a molecular switch that determines the pathway an embryo will take.
- Gonadal sex is the first thing that develops to identify whether the fetus is male or female.
- The SRY gene on the Y chromosome determines gonadal sex.
- The development of internal and external genitalia is influenced by the products of the pair of gonads.
- 5α-reductase is an enzyme that converts testosterone to DHT, which causes differentiation of the male external genitalia.
- Disorders of sexual differentiation include gonadal dysgenesis, sex reversal, and intersex.
- Androgen Insensitivity Syndrome (AIS) occurs when a patient is XY and makes testosterone, but it has no effect.
- Patients with complete AIS appear totally female at birth and are assigned the female gender despite having an XY.
- Terms such as 'pseudohermaphrodite' and 'testicular feminisation' are now obsolete.
- Undescended testes can be a sign of gonadal dysgenesis.
- Primary amenorrhoea and lack of body hair can indicate gonadal dysgenesis.
- Karyotyping can reveal the XY genotype despite a female phenotype in gonadal dysgenesis.
- Turner's syndrome is a genetic disorder that results in female external genitalia.
- Congenital adrenal hyperplasia can cause both male and female internal genitalia.
- The HPG axis is flawed in congenital adrenal hyperplasia.
- The lack of aldosterone in congenital adrenal hyperplasia can cause salt wasting.
- Glucocorticoid treatment is necessary in congenital adrenal hyperplasia.
- Surgery is now optional for partial AIS treatment.
- Turner's syndrome is a spectrum disorder.
Test your knowledge on sexual differentiation and disorders in this informative quiz! From the role of the SRY gene in determining gonadal sex to the various forms of disorders of sexual development, this quiz covers it all. You'll learn about the development of internal and external genitalia, the HPG axis, and the latest treatments for conditions like AIS and congenital adrenal hyperplasia. Sharpen your understanding of sexual differentiation and take the quiz now!
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