7 Questions
What is epigenetics?
The study of heritable changes in cellular function or gene expression
How are epigenetic changes transmitted?
Through chromatin-based molecular signals
What do epigenetic marks do?
Alter the DNA sequence
What is a common epigenetic mechanism?
DNA methylation
How does DNA methylation inhibit gene expression?
By recruiting methyl-CpG-binding proteins
Where are altered methylation states frequently observed?
In cancer cells
What is demethylation?
The process of removing methyl groups from DNA
Study Notes
- Epigenetics is the study of heritable changes in cellular function or gene expression.
- These changes are transmitted through chromatin-based molecular signals.
- Epigenetic marks do not alter the DNA sequence.
- DNA methylation is a common epigenetic mechanism.
- DNA methylation inhibits gene expression by recruiting methyl-CpG-binding proteins.
- Altered methylation states are frequently observed in cancer.
- Demethylation occurs during germ cell development and early embryonic development.
- Demethylation involves the enzymatic conversion of 5-mC to 5-hmC.
- 5-mC levels are stable across adult tissues, whereas 5-hmC levels are much lower and more variable.
- 5-hmC is found in known regulatory regions, suggesting a possible role in the regulation of specific promoters and enhancers.
Test your knowledge on the fascinating field of epigenetics with this quiz! From the study of heritable changes in cellular function to the role of DNA methylation in inhibiting gene expression, this quiz will challenge you to recall important concepts and mechanisms. Explore the differences between 5-mC and 5-hmC levels and their potential regulatory roles in specific promoters and enhancers. Brush up on your understanding of epigenetic marks and altered methylation states commonly observed in cancer. Take the quiz
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