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Questions and Answers
What is the mechanism of action of sulfonylureas in treating type 2 diabetes mellitus?
What is the mechanism of action of sulfonylureas in treating type 2 diabetes mellitus?
- They block ATP-sensitive K+ channels in β cells of the pancreas (correct)
- They increase glucose uptake in target tissues
- They decrease insulin resistance by increasing insulin secretion
- They reduce hepatic glucose production and increase peripheral insulin sensitivity
Which of the following is a common adverse effect of meglitinides?
Which of the following is a common adverse effect of meglitinides?
- Hypoglycemia (correct)
- GIT upset
- Lactic acidosis
- Hepatotoxicity
What is the therapeutic use of metformin?
What is the therapeutic use of metformin?
- Polycystic ovary syndrome only in combination with other drugs
- Type 2 diabetes mellitus only in combination with other drugs
- Type 2 diabetes mellitus either alone or in combination with other drugs (correct)
- Type 1 diabetes mellitus
