Test Your Knowledge of Virulence Factors in Bacterial and Viral Pathogens 15.3 pt 2
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Questions and Answers

Which bacterial pathogen undergoes antigenic variation of surface lipoprotein VlsE, contributing to chronic disease?

  • Escherichia coli
  • Borrelia burgdorferi (correct)
  • Staphylococcus aureus
  • Salmonella enterica

Which viral adhesin binds to the sialic acid on the membrane of host respiratory and intestinal cells?

  • Glycoprotein gp20 on HIV
  • Spike protein on SARS-CoV-2
  • Hemagglutinin on Influenzavirus (correct)
  • VP1 on Human papillomavirus

Which bacterial pathogen undergoes antigenic variation of type IV pili to avoid immune defenses?

  • Streptococcus pyogenes
  • Neisseria meningitidis
  • Neisseria gonorrhoeae (correct)
  • Pseudomonas aeruginosa

What is the function of coagulase in bacterial pathogens?

<p>Promotes clotting (A)</p> Signup and view all the answers

What is the function of staphylokinase in bacterial pathogens?

<p>Initiates clot digestion (C)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 of immune system cells for viral entry?

<p>Glycoprotein gp20 on HIV (A)</p> Signup and view all the answers

What is the mechanism of antigenic drift in enveloped viruses, including influenza viruses?

<p>Point mutations in hemagglutinin and neuraminidase (C)</p> Signup and view all the answers

What is the mechanism of antigenic shift in enveloped viruses, including influenza viruses?

<p>Major change in spike proteins due to gene reassortment (B)</p> Signup and view all the answers

What is the rate of antigenic variation in influenza viruses?

<p>Very high (A)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year (D)</p> Signup and view all the answers

What is the function of kinases in bacterial and viral pathogens?

<p>Triggers the conversion of plasminogen to plasmin (A)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of surface proteins to evade recognition by the host immune system?

<p>Streptococcus pyogenes (B)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of surface lipoprotein VlsE, contributing to chronic disease?

<p>Borrelia burgdorferi (C)</p> Signup and view all the answers

Which viral adhesin binds to the sialic acid on the membrane of host respiratory and intestinal cells?

<p>Hemagglutinin on Influenzavirus (C)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (C)</p> Signup and view all the answers

What is the function of coagulase in bacterial pathogens?

<p>Promotes clotting (A)</p> Signup and view all the answers

What is the function of staphylokinase in bacterial pathogens?

<p>Initiates clot digestion (C)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 of immune system cells for viral entry?

<p>Glycoprotein gp20 on HIV (D)</p> Signup and view all the answers

What is the mechanism of antigenic drift in enveloped viruses, including influenza viruses?

<p>Point mutations in hemagglutinin and neuraminidase (D)</p> Signup and view all the answers

What is the mechanism of antigenic shift in enveloped viruses, including influenza viruses?

<p>Major change in spike proteins due to gene reassortment (D)</p> Signup and view all the answers

What is the rate of antigenic variation in influenza viruses?

<p>Very high (A)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year (C)</p> Signup and view all the answers

What is the function of kinases in bacterial and viral pathogens?

<p>Triggers the conversion of plasminogen to plasmin (C)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of surface proteins to evade recognition by the host immune system?

<p>Streptococcus pyogenes (A)</p> Signup and view all the answers

What is the function of coagulase in bacterial pathogens?

<p>Promotes clotting and provides a protective barrier from the immune system (B)</p> Signup and view all the answers

What is antigenic variation in pathogens?

<p>The alteration of surface proteins to evade recognition by the host immune system (B)</p> Signup and view all the answers

Which pathogen undergoes antigenic variation of surface lipoprotein VlsE?

<p>Borrelia burgdorferi, the causative agent of Lyme disease (B)</p> Signup and view all the answers

Which pathogen undergoes antigenic variation of type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae, which causes gonorrhea (D)</p> Signup and view all the answers

What is the function of viral adhesins in viral pathogens?

<p>Mediate the adhesion of the virus to specific receptors on the surface of cells, defining their tropism (C)</p> Signup and view all the answers

What does hemagglutinin on Influenzavirus bind to on the host cells?

<p>Sialic acid on the membrane of host respiratory and intestinal cells (B)</p> Signup and view all the answers

What does glycoprotein gp20 on HIV interact with on immune system cells for viral entry?

<p>CD4 and CCR5 or CXCR4 (C)</p> Signup and view all the answers

What is antigenic drift in enveloped viruses like influenza viruses?

<p>Caused by point mutations in hemagglutinin and neuraminidase (C)</p> Signup and view all the answers

What is antigenic shift in enveloped viruses like influenza viruses?

<p>A major change in spike proteins due to gene reassortment (D)</p> Signup and view all the answers

Why is it difficult for the immune system to recognize different strains of influenza viruses?

<p>The rate of antigenic variation is high (B)</p> Signup and view all the answers

What do annual influenza vaccines provide protection against?

<p>The most prevalent strains for that year (B)</p> Signup and view all the answers

What triggers the conversion of plasminogen to plasmin in bacterial pathogens?

<p>Kinases (C)</p> Signup and view all the answers

Which enzyme digests fibrin clots and allows pathogens to escape and spread?

<p>Staphylokinase (C)</p> Signup and view all the answers

What is antigenic variation?

<p>The alteration of surface proteins to avoid recognition by the host's immune system (B)</p> Signup and view all the answers

Which pathogen uses antigenic variation in the surface lipoprotein VlsE to cause chronic disease?

<p>Borrelia burgdorferi (D)</p> Signup and view all the answers

Which pathogen undergoes antigenic variation of its type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (B)</p> Signup and view all the answers

What are adhesins in viruses?

<p>Part of the viral capsid or membrane envelope that define the tropism of viruses for specific cells and tissues (A)</p> Signup and view all the answers

What is the spike protein hemagglutinin found on Influenzavirus an example of?

<p>A viral adhesin that allows the virus to bind to the sialic acid on the membrane of host respiratory and intestinal cells (A)</p> Signup and view all the answers

What does HIV use to interact with CD4 and CCR5 or CXCR4 receptors on the surface of immune system cells?

<p>Glycoprotein gp120 (B)</p> Signup and view all the answers

What is antigenic drift in influenza viruses?

<p>The high rate of antigenic variation caused by point mutations (B)</p> Signup and view all the answers

What is antigenic shift in influenza viruses?

<p>The process of gene reassortment leading to the emergence of new viral strains (D)</p> Signup and view all the answers

Why is it difficult for the immune system to recognize all strains of influenza viruses?

<p>Due to the high rate of antigenic variation (C)</p> Signup and view all the answers

What does each year's influenza vaccine provide protection against?

<p>The most prevalent strains for that year (B)</p> Signup and view all the answers

What is the function of coagulase produced by Staphylococcus aureus?

<p>To promote clotting (D)</p> Signup and view all the answers

What is the function of adhesins in viral pathogens?

<p>They are part of the viral capsid or membrane envelope and define the tropism of viruses for specific cells and tissues. (B)</p> Signup and view all the answers

Which bacterial pathogen produces both coagulase and staphylokinase to promote clotting and stimulate the digestion of clots, respectively?

<p>Staphylococcus aureus (B)</p> Signup and view all the answers

What is antigenic variation in pathogens?

<p>The alteration of surface proteins to avoid recognition by the host's immune system. (C)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of its type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (D)</p> Signup and view all the answers

What is the function of the spike protein hemagglutinin found on Influenzavirus?

<p>It allows the virus to bind to the sialic acid on the membrane of host respiratory and intestinal cells. (D)</p> Signup and view all the answers

What is the mechanism of antigenic drift in enveloped viruses, including influenza viruses?

<p>It is caused by point mutations. (C)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 receptors on the surface of immune system cells for viral entry?

<p>Gp120 (A)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year. (B)</p> Signup and view all the answers

What is the mechanism of antigenic shift in enveloped viruses, including influenza viruses?

<p>It occurs through gene reassortment. (A)</p> Signup and view all the answers

What is the effect of antigenic variation in Borrelia burgdorferi, the causative agent of Lyme disease?

<p>It causes chronic disease in the host. (C)</p> Signup and view all the answers

What is the effect of antigenic variation in Neisseria gonorrhoeae, which causes gonorrhea?

<p>It alters surface proteins to avoid recognition by the host's immune system. (C)</p> Signup and view all the answers

What is the effect of antigenic variation in enveloped viruses, including influenza viruses?

<p>It alters surface proteins to avoid recognition by the host's immune system. (C)</p> Signup and view all the answers

What is the function of adhesins in viral pathogens?

<p>To facilitate adhesion to host cells and define tropism for specific cells and tissues (D)</p> Signup and view all the answers

Which bacterial pathogen produces both coagulase and staphylokinase to promote clotting and stimulate the digestion of clots, respectively?

<p>Staphylococcus aureus (A)</p> Signup and view all the answers

What is the mechanism of antigenic variation in bacterial pathogens?

<p>Alteration of surface proteins (B)</p> Signup and view all the answers

Which enveloped virus relies on antigenic variation to avoid host immune defenses?

<p>Influenzavirus (B)</p> Signup and view all the answers

What is the function of the spike protein hemagglutinin found on Influenzavirus?

<p>To facilitate adhesion to host cells and define tropism for specific cells and tissues (C)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 receptors on the surface of immune system cells?

<p>gp120 (D)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year (C)</p> Signup and view all the answers

What is the mechanism of antigenic drift in enveloped viruses, including influenza viruses?

<p>Point mutations (A)</p> Signup and view all the answers

What is the mechanism of antigenic shift in enveloped viruses, including influenza viruses?

<p>Gene reassortment (C)</p> Signup and view all the answers

What is the rate of antigenic variation in influenza viruses?

<p>Very high (A)</p> Signup and view all the answers

What is the function of kinases in bacterial and viral pathogens?

<p>To trigger the conversion of plasminogen to plasmin (C)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of its type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (A)</p> Signup and view all the answers

Which bacterial pathogen uses antigenic variation in the surface lipoprotein VlsE to cause chronic disease?

<p>Borrelia burgdorferi (D)</p> Signup and view all the answers

What is the function of adhesins in viral pathogens?

<p>To facilitate adhesion to host cells and define the tropism of viruses for specific cells and tissues (B)</p> Signup and view all the answers

Which bacterial pathogen produces both coagulase and staphylokinase to promote clotting and stimulate the digestion of clots, respectively?

<p>Staphylococcus aureus (A)</p> Signup and view all the answers

What is antigenic variation in pathogens?

<p>The alteration of surface proteins to avoid recognition by the host's immune system (C)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of its type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (C)</p> Signup and view all the answers

What is the function of kinases in pathogens?

<p>To produce enzymes that digest fibrin clots and allow pathogens to escape and spread (B)</p> Signup and view all the answers

Which viral adhesin binds to the sialic acid on the membrane of host respiratory and intestinal cells?

<p>Spike protein hemagglutinin (C)</p> Signup and view all the answers

What is the mechanism of antigenic drift in influenza viruses?

<p>Point mutations (B)</p> Signup and view all the answers

What is the mechanism of antigenic shift in influenza viruses?

<p>Gene reassortment (C)</p> Signup and view all the answers

What is the rate of antigenic variation in influenza viruses?

<p>High (A)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To protect against the most prevalent strains of influenza viruses for that year (C)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 receptors on the surface of immune system cells for viral entry?

<p>Glycoprotein gp120 (D)</p> Signup and view all the answers

Which bacterial pathogen uses antigenic variation in the surface lipoprotein VlsE to cause chronic disease?

<p>Borrelia burgdorferi (A)</p> Signup and view all the answers

What is the function of antigenic variation in pathogens?

<p>To avoid recognition by the host's immune system (B)</p> Signup and view all the answers

Which bacterial pathogen uses both coagulase and staphylokinase to promote clotting and stimulate the digestion of clots, respectively?

<p>Staphylococcus aureus (C)</p> Signup and view all the answers

What is the function of adhesins in viruses?

<p>To facilitate adhesion to host cells (C)</p> Signup and view all the answers

Which viral adhesin binds to CD4 and CCR5 or CXCR4 receptors on the surface of immune system cells for viral entry?

<p>Gp120 (D)</p> Signup and view all the answers

What is the mechanism of antigenic drift in influenza viruses?

<p>Point mutations (B)</p> Signup and view all the answers

What is the mechanism of antigenic shift in influenza viruses?

<p>Gene reassortment (A)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year (B)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of its type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (B)</p> Signup and view all the answers

What is the function of kinases in pathogens?

<p>To trigger the conversion of plasminogen to plasmin (C)</p> Signup and view all the answers

Which enveloped viruses rely on antigenic variation to avoid host immune defenses?

<p>Specific enveloped viruses (D)</p> Signup and view all the answers

What is the surface lipoprotein used by Borrelia burgdorferi to cause chronic disease through antigenic variation?

<p>VlsE (C)</p> Signup and view all the answers

What is the antigenic variation in influenza viruses caused by?

<p>Both gene reassortment and point mutations (B)</p> Signup and view all the answers

What is the function of adhesins in viral pathogens?

<p>To facilitate adhesion to host cells and define the tropism of viruses for specific cells and tissues (D)</p> Signup and view all the answers

What is the causative agent of Lyme disease?

<p>Borrelia burgdorferi (D)</p> Signup and view all the answers

Which bacterial pathogen produces both coagulase and staphylokinase to promote clotting and stimulate the digestion of clots?

<p>Staphylococcus aureus (C)</p> Signup and view all the answers

What is the mechanism of antigenic variation in Neisseria gonorrhoeae?

<p>Alteration of type IV pili (D)</p> Signup and view all the answers

What is the function of kinases in bacterial and viral pathogens?

<p>To trigger the conversion of plasminogen to plasmin (D)</p> Signup and view all the answers

What is the function of staphylokinase in bacterial pathogens?

<p>To digest fibrin clots and allow pathogens to escape and spread (D)</p> Signup and view all the answers

What is the function of coagulase in bacterial pathogens?

<p>To trigger the conversion of plasminogen to plasmin (D)</p> Signup and view all the answers

What is the mechanism of antigenic drift in enveloped viruses, including influenza viruses?

<p>Point mutations (D)</p> Signup and view all the answers

What is the mechanism of antigenic shift in enveloped viruses, including influenza viruses?

<p>Gene reassortment (A)</p> Signup and view all the answers

What is the rate of antigenic variation in influenza viruses?

<p>Very high (C)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year (A)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 of immune system cells for viral entry?

<p>gp120 (D)</p> Signup and view all the answers

What is the function of staphylokinase in Staphylococcus aureus infections?

<p>To digest fibrin clots (D)</p> Signup and view all the answers

What is the purpose of antigenic variation in pathogens?

<p>To avoid recognition by the host immune system (D)</p> Signup and view all the answers

What is the function of adhesins in viral infections?

<p>To promote adhesion to host cells (B)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 receptors on the surface of immune system cells for viral entry?

<p>Gp120 (D)</p> Signup and view all the answers

What is the mechanism of antigenic drift in enveloped viruses, including influenza viruses?

<p>Point mutations (D)</p> Signup and view all the answers

What is the mechanism of antigenic shift in enveloped viruses, including influenza viruses?

<p>Gene reassortment (B)</p> Signup and view all the answers

What is the high rate of antigenic variation in influenza viruses due to?

<p>Point mutations (C)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year (C)</p> Signup and view all the answers

What is the function of kinases in pathogen infections?

<p>To digest fibrin clots (D)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of its type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (A)</p> Signup and view all the answers

Which bacterial pathogen uses antigenic variation in the surface lipoprotein VlsE to cause chronic disease?

<p>Borrelia burgdorferi (C)</p> Signup and view all the answers

Which enveloped virus uses the spike protein hemagglutinin to bind to the sialic acid on the membrane of host respiratory and intestinal cells?

<p>Influenzavirus (A)</p> Signup and view all the answers

What is the function of adhesins in viruses?

<p>To facilitate adhesion to host cells (C)</p> Signup and view all the answers

Which bacterial pathogen produces both coagulase and staphylokinase to protect itself and escape?

<p>Staphylococcus aureus (D)</p> Signup and view all the answers

What is antigenic variation in pathogens?

<p>The alteration of surface proteins to avoid recognition by the host's immune system (B)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of its type IV pili to evade immune defenses?

<p>Neisseria gonorrhoeae (A)</p> Signup and view all the answers

What is the function of kinases in pathogens?

<p>To trigger the conversion of plasminogen to plasmin (A)</p> Signup and view all the answers

What is the viral adhesin that binds to the sialic acid on the membrane of host respiratory and intestinal cells?

<p>Hemagglutinin (A)</p> Signup and view all the answers

What is the mechanism of antigenic drift in influenza viruses?

<p>Point mutations (B)</p> Signup and view all the answers

What is the mechanism of antigenic shift in influenza viruses?

<p>Gene reassortment (D)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year (A)</p> Signup and view all the answers

Which viral glycoprotein interacts with CD4 and CCR5 or CXCR4 of immune system cells for viral entry?

<p>Gp120 (A)</p> Signup and view all the answers

What is the bacterial pathogen that uses antigenic variation in the surface lipoprotein VlsE to cause chronic disease?

<p>Borrelia burgdorferi (D)</p> Signup and view all the answers

What is the high rate of antigenic variation in influenza viruses attributed to?

<p>Point mutations (D)</p> Signup and view all the answers

What is the function of adhesins in viral pathogens?

<p>To facilitate adhesion to host cells. (C)</p> Signup and view all the answers

Which bacterial pathogen produces both coagulase and staphylokinase to protect itself and escape from the host's immune system?

<p>Staphylococcus aureus (A)</p> Signup and view all the answers

What is the mechanism of antigenic variation in bacterial pathogens?

<p>Alteration of surface proteins. (D)</p> Signup and view all the answers

Which enveloped virus relies on antigenic variation to avoid host immune defenses?

<p>Influenzavirus (C)</p> Signup and view all the answers

Which bacterial pathogen undergoes antigenic variation of its type IV pili to avoid immune defenses?

<p>Neisseria gonorrhoeae (A)</p> Signup and view all the answers

What is the function of the spike protein hemagglutinin found on Influenzavirus?

<p>To bind to the sialic acid on the membrane of host respiratory and intestinal cells. (A)</p> Signup and view all the answers

What is the function of gp120 in HIV?

<p>To interact with CD4 and CCR5 or CXCR4 receptors on the surface of immune system cells. (D)</p> Signup and view all the answers

What is antigenic drift in influenza viruses caused by?

<p>Point mutations. (C)</p> Signup and view all the answers

What is antigenic shift in influenza viruses caused by?

<p>Gene reassortment. (B)</p> Signup and view all the answers

What is the purpose of annual influenza vaccines?

<p>To provide protection against the most prevalent strains for that year. (B)</p> Signup and view all the answers

What is the rate of antigenic variation in influenza viruses?

<p>Very high (B)</p> Signup and view all the answers

What is the function of kinases in bacterial and viral pathogens?

<p>To trigger the conversion of plasminogen to plasmin. (B)</p> Signup and view all the answers

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