Podcast
Questions and Answers
Which type of RNA structure is stabilized by interactions between two or more secondary structure elements and metal cations such as Na+ and Mg2+?
Which type of RNA structure is stabilized by interactions between two or more secondary structure elements and metal cations such as Na+ and Mg2+?
What is the primary sequence of an RNA molecule?
What is the primary sequence of an RNA molecule?
What is the predominant building block of RNA's secondary structure?
What is the predominant building block of RNA's secondary structure?
What is the arrangement described by RNA quaternary structure?
What is the arrangement described by RNA quaternary structure?
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What is the function of some unstructured single-stranded RNA molecules?
What is the function of some unstructured single-stranded RNA molecules?
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What is the name for a structure that forms when one or more nucleotides on each RNA strand are unpaired?
What is the name for a structure that forms when one or more nucleotides on each RNA strand are unpaired?
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What is the name for a structure that forms when a strand folds back to form a stem that contains Watson-Crick base pairs and a loop?
What is the name for a structure that forms when a strand folds back to form a stem that contains Watson-Crick base pairs and a loop?
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What is the smallest known RNA catalyst?
What is the smallest known RNA catalyst?
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What is the function of ribozymes?
What is the function of ribozymes?
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Which of the following best describes the primary structure of an RNA molecule?
Which of the following best describes the primary structure of an RNA molecule?
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What are ribozymes?
What are ribozymes?
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What is the predominant secondary structure building block in RNA molecules?
What is the predominant secondary structure building block in RNA molecules?
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What stabilizes RNA tertiary structures?
What stabilizes RNA tertiary structures?
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What are some specific structural elements that contribute to RNA tertiary structure?
What are some specific structural elements that contribute to RNA tertiary structure?
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What is RNA quaternary structure?
What is RNA quaternary structure?
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Do all RNA molecules assume a specific three-dimensional structure?
Do all RNA molecules assume a specific three-dimensional structure?
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What is an internal loop in RNA secondary structure?
What is an internal loop in RNA secondary structure?
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What is the smallest known RNA catalyst?
What is the smallest known RNA catalyst?
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Study Notes
RNA Structure: From Secondary to Tertiary and Quaternary Structures
- RNA performs various functions in the cell, including as genetic material in some viruses and contributing to polypeptide synthesis.
- In the 1980s, ribozymes were discovered, demonstrating that RNA molecules can act as catalysts.
- RNA structure, like protein structure, is divided into primary, secondary, tertiary, and quaternary structures.
- The primary sequence of an RNA molecule is its base sequence, while secondary structure is dominated by Watson-Crick base pairs.
- RNA's predominant secondary structure building blocks are helical tracts, which are stabilized by Watson-Crick base pairing.
- RNA tertiary structures are stabilized by interactions between two or more secondary structure elements, and metal cations such as Na+ and Mg2+.
- Specific structural elements contribute to the tertiary structure, such as pseudoknots, kissing hairpins, and hairpin loop-bulge contacts.
- RNA quaternary structure describes the arrangement of an RNA molecule with respect to other RNA molecules or with protein molecules.
- Some kinds of RNA molecules do not assume a specific three-dimensional structure but instead function as unstructured single strands.
- RNA's secondary structure consists of helical regions and various kinds of loops, bulges, and junctions within the helical regions.
- An internal loop forms when one or more nucleotides on each RNA strand are unpaired, and hairpin structures form when a strand folds back to form a stem that contains Watson-Crick base pairs and a loop.
- Crystal structures have been determined for many RNA molecules, including the hammerhead ribozyme, the smallest known RNA catalyst.
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Description
Test your knowledge of RNA structure from secondary to tertiary and quaternary structures with this quiz! Explore the building blocks of RNA, the role of Watson-Crick base pairing, and the stabilizing factors that contribute to RNA's tertiary structure. Delve into specific structural elements like pseudoknots, kissing hairpins, and hairpin loop-bulge contacts. Discover the importance of RNA quaternary structure, and learn about the crystal structures of various RNA molecules. Take this quiz to deepen your