Test your knowledge of Entresto, a medication used for the treatment of CHF. Lea...
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Questions and Answers

What is the composition of Entresto in terms of Sacubitril and Valsartan?

  • 2:1 mixture by molecule count
  • 1:2 mixture by molecule count
  • 1:1 mixture by molecule count (correct)
  • 3:2 mixture by molecule count

Which enzyme hydrolyzes Sacubitril to the dicarboxylic acid derivative?

  • Lipase
  • Protease
  • Kinase
  • Esterase (correct)

What are the main pharmacological properties of Sacubitril and Valsartan in Entresto?

  • ACE inhibitor and beta blocker
  • Neprilysin inhibitor and AT1 blocker (correct)
  • Calcium channel blocker and diuretic
  • Alpha blocker and potassium-sparing diuretic
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