Podcast
Questions and Answers
What is the composition of Entresto in terms of Sacubitril and Valsartan?
What is the composition of Entresto in terms of Sacubitril and Valsartan?
- 2:1 mixture by molecule count
- 1:2 mixture by molecule count
- 1:1 mixture by molecule count (correct)
- 3:2 mixture by molecule count
Which enzyme hydrolyzes Sacubitril to the dicarboxylic acid derivative?
Which enzyme hydrolyzes Sacubitril to the dicarboxylic acid derivative?
- Lipase
- Protease
- Kinase
- Esterase (correct)
What are the main pharmacological properties of Sacubitril and Valsartan in Entresto?
What are the main pharmacological properties of Sacubitril and Valsartan in Entresto?
- ACE inhibitor and beta blocker
- Neprilysin inhibitor and AT1 blocker (correct)
- Calcium channel blocker and diuretic
- Alpha blocker and potassium-sparing diuretic