Test Your Hematology Knowledge
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Questions and Answers

What are the two stages of hemostasis?

  • Primary and secondary (correct)
  • Prothrombin and fibrinogen
  • Contact and common
  • Intrinsic and extrinsic
  • Which coagulation factors are part of the prothrombin group?

  • XI, XII, PK, and HK
  • None of the above
  • I, V, VIII, and XIII
  • II, VII, IX, and X (correct)
  • What is the function of fibrinolysis?

  • Forming a platelet plug
  • Transforming fibrinogen into fibrin
  • Activating the intrinsic pathway
  • Removing fibrin (correct)
  • Which coagulation proteins are not found in serum?

    <p>I, V, VIII, and XIII</p> Signup and view all the answers

    What is the role of activated platelets in coagulation?

    <p>Provide phospholipid for coagulation</p> Signup and view all the answers

    What are the three classifications of anemia based on MCV?

    <p>Normocytic, microcytic, and macrocytic</p> Signup and view all the answers

    Which coagulation proteins are involved in the initial activation of the intrinsic pathway?

    <p>XI, XII, PK, and HK</p> Signup and view all the answers

    What is the role of secondary hemostasis in hemostasis?

    <p>Reinforces the platelet plug</p> Signup and view all the answers

    Which coagulation proteins require vitamin K to be functional?

    <p>II, VII, IX, and X</p> Signup and view all the answers

    What is the function of the platelet-fibrin plug in hemostasis?

    <p>Seals the injured vessel</p> Signup and view all the answers

    What are the three classifications of anemia based on MCHC?

    <p>Normochromic, hypochromic, and hyperchromic</p> Signup and view all the answers

    What are the three groups of coagulation proteins?

    <p>Prothrombin group, fibrinogen group, and contact group</p> Signup and view all the answers

    Which stage of hemostasis involves the formation of an unstable platelet plug?

    <p>Primary hemostasis</p> Signup and view all the answers

    What is the purpose of secondary hemostasis?

    <p>To reinforce the unstable platelet plug</p> Signup and view all the answers

    Which of the following is NOT a coagulation factor in the Prothrombin group?

    <p>Factor IV</p> Signup and view all the answers

    Which coagulation factor group is not found in serum because they are consumed during coagulation?

    <p>Fibrinogen group</p> Signup and view all the answers

    Which group of coagulation factors is involved in the initial activation of intrinsic pathway and requires a negatively charged surface for activation?

    <p>Contact group</p> Signup and view all the answers

    Where do most coagulation reactions occur?

    <p>On the surface membrane of activated platelets</p> Signup and view all the answers

    What is fibrinolysis?

    <p>The process of removing fibrin to lyse the clot following repair to the vessel wall</p> Signup and view all the answers

    Which erythrocyte index helps classify erythrocytes based on their size?

    <p>Mean Cell Volume (MCV)</p> Signup and view all the answers

    Which erythrocyte index helps classify erythrocytes based on their hemoglobin content?

    <p>Mean Corpuscular Hemoglobin (MCH)</p> Signup and view all the answers

    Which erythrocyte index helps classify anemia?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is NOT a coagulation pathway?

    <p>All of the above are coagulation pathways</p> Signup and view all the answers

    Which group of coagulation factors is vitamin K dependent and produced in the liver?

    <p>Prothrombin group</p> Signup and view all the answers

    Study Notes

    Secondary Hemostasis and Fibrinolysis

    • Hemostasis consists of two stages: primary and secondary.
    • Primary hemostasis involves the formation of an unstable platelet plug.
    • Secondary hemostasis reinforces the unstable platelet plug by transforming soluble fibrinogen into insoluble fibrin, which seals the injured vessel and initiates fibrinolysis.
    • Coagulation mechanism involves intrinsic pathway, extrinsic pathway, and common pathway.
    • Coagulation factors assigned Roman numerals I to XIII and divided into three groups: Prothrombin, Fibrinogen, and Contact groups.
    • The Prothrombin group (II, VII, IX, X) is vitamin K dependent and produced in the liver.
    • The Fibrinogen group (I, V, VIII, XIII) is not found in serum because they are consumed during coagulation.
    • The Contact group (XI, XII, PK, HK) is involved in the initial activation of intrinsic pathway and requires a negatively charged surface for activation.
    • Most coagulation reactions occur on the surface membrane of activated platelets, which provide the critical phospholipid for coagulation.
    • Fibrinolysis is the process of removing fibrin to lyse the clot following repair to the vessel wall.
    • Erythrocyte indices help classify erythrocytes based on their size and hemoglobin content.
    • The three indices are Mean Cell Volume (MCV), Mean Corpuscular Hemoglobin (MCH), and Mean Corpuscular Hemoglobin Concentration (MCHC). They are used to classify anemia.

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    Test your knowledge of Secondary Hemostasis and Fibrinolysis with this quiz! This quiz covers the stages of hemostasis, the coagulation mechanism, and the different coagulation factors and proteins involved. You'll also be tested on your understanding of fibrinolysis and the classification of anemia based on erythrocyte indices. This quiz is perfect for anyone studying hematology or those looking to refresh their knowledge on secondary hemostasis and fibrinolysis.

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