24 Questions
What are the two stages of hemostasis?
Primary and secondary
Which coagulation factors are part of the prothrombin group?
II, VII, IX, and X
What is the function of fibrinolysis?
Removing fibrin
Which coagulation proteins are not found in serum?
I, V, VIII, and XIII
What is the role of activated platelets in coagulation?
Provide phospholipid for coagulation
What are the three classifications of anemia based on MCV?
Normocytic, microcytic, and macrocytic
Which coagulation proteins are involved in the initial activation of the intrinsic pathway?
XI, XII, PK, and HK
What is the role of secondary hemostasis in hemostasis?
Reinforces the platelet plug
Which coagulation proteins require vitamin K to be functional?
II, VII, IX, and X
What is the function of the platelet-fibrin plug in hemostasis?
Seals the injured vessel
What are the three classifications of anemia based on MCHC?
Normochromic, hypochromic, and hyperchromic
What are the three groups of coagulation proteins?
Prothrombin group, fibrinogen group, and contact group
Which stage of hemostasis involves the formation of an unstable platelet plug?
Primary hemostasis
What is the purpose of secondary hemostasis?
To reinforce the unstable platelet plug
Which of the following is NOT a coagulation factor in the Prothrombin group?
Factor IV
Which coagulation factor group is not found in serum because they are consumed during coagulation?
Fibrinogen group
Which group of coagulation factors is involved in the initial activation of intrinsic pathway and requires a negatively charged surface for activation?
Contact group
Where do most coagulation reactions occur?
On the surface membrane of activated platelets
What is fibrinolysis?
The process of removing fibrin to lyse the clot following repair to the vessel wall
Which erythrocyte index helps classify erythrocytes based on their size?
Mean Cell Volume (MCV)
Which erythrocyte index helps classify erythrocytes based on their hemoglobin content?
Mean Corpuscular Hemoglobin (MCH)
Which erythrocyte index helps classify anemia?
All of the above
Which of the following is NOT a coagulation pathway?
All of the above are coagulation pathways
Which group of coagulation factors is vitamin K dependent and produced in the liver?
Prothrombin group
Study Notes
Secondary Hemostasis and Fibrinolysis
- Hemostasis consists of two stages: primary and secondary.
- Primary hemostasis involves the formation of an unstable platelet plug.
- Secondary hemostasis reinforces the unstable platelet plug by transforming soluble fibrinogen into insoluble fibrin, which seals the injured vessel and initiates fibrinolysis.
- Coagulation mechanism involves intrinsic pathway, extrinsic pathway, and common pathway.
- Coagulation factors assigned Roman numerals I to XIII and divided into three groups: Prothrombin, Fibrinogen, and Contact groups.
- The Prothrombin group (II, VII, IX, X) is vitamin K dependent and produced in the liver.
- The Fibrinogen group (I, V, VIII, XIII) is not found in serum because they are consumed during coagulation.
- The Contact group (XI, XII, PK, HK) is involved in the initial activation of intrinsic pathway and requires a negatively charged surface for activation.
- Most coagulation reactions occur on the surface membrane of activated platelets, which provide the critical phospholipid for coagulation.
- Fibrinolysis is the process of removing fibrin to lyse the clot following repair to the vessel wall.
- Erythrocyte indices help classify erythrocytes based on their size and hemoglobin content.
- The three indices are Mean Cell Volume (MCV), Mean Corpuscular Hemoglobin (MCH), and Mean Corpuscular Hemoglobin Concentration (MCHC). They are used to classify anemia.
Test your knowledge of Secondary Hemostasis and Fibrinolysis with this quiz! This quiz covers the stages of hemostasis, the coagulation mechanism, and the different coagulation factors and proteins involved. You'll also be tested on your understanding of fibrinolysis and the classification of anemia based on erythrocyte indices. This quiz is perfect for anyone studying hematology or those looking to refresh their knowledge on secondary hemostasis and fibrinolysis.
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