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Questions and Answers
What is the role of release factors during the termination phase of translation?
What is the role of release factors during the termination phase of translation?
Which of the following events does NOT occur during the termination phase?
Which of the following events does NOT occur during the termination phase?
Which of the following release factors binds to the stop codon UAG?
Which of the following release factors binds to the stop codon UAG?
What is the role of RF3 in the termination phase?
What is the role of RF3 in the termination phase?
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What provides the energy required for the separation of the translation complex during termination?
What provides the energy required for the separation of the translation complex during termination?
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Flashcards
Termination Phase
Termination Phase
The phase where protein synthesis stops when a stop codon is reached.
Stop Codons
Stop Codons
Codons (UAA, UGA, UAG) that signal the end of protein synthesis.
Release Factors (RFs)
Release Factors (RFs)
Proteins that bind to stop codons to terminate translation.
RF1 and RF2
RF1 and RF2
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GTP in Termination
GTP in Termination
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Study Notes
Termination Phase
- Termination begins when a stop codon (UAA, UGA, or UAG) is reached.
- Stop codons are not recognised by tRNA molecules.
- Release Factors (RFs) bind to the A site of the ribosome.
- RF1 binds to UAA and UAG.
- RF2 binds to UAA and UGA.
- RF3 facilitates the function of RF1 and RF2.
- Ribosome disassembly occurs, releasing the polypeptide chain, tRNA, mRNA, and RFs.
- GTP provides energy for this process.
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Description
This quiz covers the termination phase of translation in protein synthesis. Key concepts include the recognition of stop codons, the role of release factors, and the disassembly of the ribosome. Test your understanding of how polypeptides are released in this vital biological process.