Questions and Answers
What class of drugs does terazosin belong to?
What is the mechanism of action of terazosin?
Alpha-1 antagonist
Which of the following conditions is terazosin indicated for? (Select all that apply)
What are some side effects of terazosin?
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What precautions should be taken when using terazosin?
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What is the route of administration for terazosin?
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What is the initial dose of terazosin?
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The maximum dose of terazosin per day is ______.
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Which of the following are contraindications for terazosin? (Select all that apply)
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Study Notes
Terazosin Overview
- Terazosin belongs to the "azosin" drug class, categorized as alpha blockers or adrenergic antagonists.
- Functions mainly as an alpha-1 antagonist, inhibiting the action of norepinephrine on alpha-1 adrenergic receptors.
Indications
- Prescribed for hypertension (high blood pressure) management.
- Effective in treating benign prostatic hyperplasia (BPH), which is the enlargement of the prostate.
- Used in the treatment of Raynaud's disease, a condition that affects blood flow to certain parts of the body.
Mechanism of Action
- Primarily works by blocking alpha-1 receptors, leading to vasodilation and a reduction in peripheral vascular resistance (PVR).
- Results in reduced blood pressure; however, there is less reflex increase in cardiac output due to sparing of alpha-2 receptors.
Side Effects
- Possible side effects include dizziness and vertigo due to changes in blood pressure.
- Can cause tachycardia (increased heart rate) and hypotension (lowered blood pressure).
- Monitoring is essential due to risks of orthostatic hypotension, where blood pressure drops upon standing.
Precautions
- Caution advised for patients experiencing dizziness, vertigo, or orthostatic hypotension.
- Alert to tachycardia and hypotension signs, as these can arise from the medication's effects.
Administration and Dosage
- Administered orally, typically taken once a day at bedtime to enhance compliance and reduce dizziness.
- Initial dosage starts at 1 mg; maintenance dosage ranges from 1 to 5 mg daily.
- Maximum allowable dosage is 20 mg per day.
Contraindications
- Not suitable for individuals unable to empty their bladder or those with prostate hyperplasia.
- Concurrent use of terazosin and alcohol is discouraged, as it may exacerbate blood pressure lowering effects.
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Description
Test your knowledge on terazosin with these flashcards! Covering drug class, mechanism of action, indications, side effects, and precautions, this quiz is an essential tool for anyone studying pharmacology. Perfect for students or professionals looking to reinforce their understanding.
