Podcast
Questions and Answers
What were the results of the Quality of Life after Treatment for Brain Metastases (QUARTZ) study when comparing dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy?
What were the results of the Quality of Life after Treatment for Brain Metastases (QUARTZ) study when comparing dexamethasone and supportive care with or without whole brain radiotherapy in treating patients with non-small cell lung cancer with brain metastases unsuitable for resection or stereotactic radiotherapy?
- A trend towards increased overall survival in the whole brain radiotherapy arm
- A statistically significant increase in overall survival in the whole brain radiotherapy arm
- No difference in overall survival between the two arms (correct)
- A substantial increase in quality-adjusted life years (QALYs) in the dexamethasone and supportive care only arm
Where is the caudal border of the cauda equina usually located?
Where is the caudal border of the cauda equina usually located?
- At the level of L1-2
- At the level of L4
- At the level of L2
- At the level of S1-S2 (correct)
What was the 5-year overall survival for MGMT-methylated glioblastoma multiforme treated with radiation plus temozolomide in the EORTC/NCIC trial (Stupp et al. Lancet Onc 2009) for glioblastoma multiforme?
What was the 5-year overall survival for MGMT-methylated glioblastoma multiforme treated with radiation plus temozolomide in the EORTC/NCIC trial (Stupp et al. Lancet Onc 2009) for glioblastoma multiforme?
- 8%
- 14% (correct)
- 0%
- 5%
Which systemic therapy provides an overall survival benefit in conjunction with adjuvant radiation for patients with 1p/19q non-codeleted anaplastic gliomas?
Which systemic therapy provides an overall survival benefit in conjunction with adjuvant radiation for patients with 1p/19q non-codeleted anaplastic gliomas?
What is the daily temozolomide dose during radiation treatment according to RTOG 08-25?
What is the daily temozolomide dose during radiation treatment according to RTOG 08-25?
How many cycles of adjuvant temozolomide were mandatory according to RTOG 08-25?
How many cycles of adjuvant temozolomide were mandatory according to RTOG 08-25?
At what dose does adjuvant temozolomide start after completing radiation according to RTOG 08-25?
At what dose does adjuvant temozolomide start after completing radiation according to RTOG 08-25?
What was the maximum dose of adjuvant temozolomide if no adverse events were observed according to RTOG 08-25?
What was the maximum dose of adjuvant temozolomide if no adverse events were observed according to RTOG 08-25?
What was the duration of one cycle of adjuvant temozolomide according to RTOG 08-25?
What was the duration of one cycle of adjuvant temozolomide according to RTOG 08-25?
What was the concurrent dose of temozolomide during radiotherapy according to RTOG 08-25?
What was the concurrent dose of temozolomide during radiotherapy according to RTOG 08-25?
