Podcast
Questions and Answers
What is the role of telomerase in DNA replication?
What is the role of telomerase in DNA replication?
- Synthesizes telomere DNA repeat at the 5' end of the leading strand (correct)
- Fills the gaps in the lagging strand
- Removes RNA primers from the lagging strand
- Seals the DNA fragments
What is the directionality of polymerase when adding nucleotides to DNA?
What is the directionality of polymerase when adding nucleotides to DNA?
- 5'-3' (correct)
- 3'-3'
- 3'-5'
- 5'-5'
In which type of cells does telomerase synthesize telomeric repeats continuously?
In which type of cells does telomerase synthesize telomeric repeats continuously?
- Prokaryotic cells
- Eukaryotic germ cells (correct)
- Somatic cells
- Plant cells
What is the role of polymerase a (primase) in DNA replication?
What is the role of polymerase a (primase) in DNA replication?
Which polymerase fills the gap till it hits the 5’ end of the lagging strand?
Which polymerase fills the gap till it hits the 5’ end of the lagging strand?
What is the role of ligase in DNA replication?
What is the role of ligase in DNA replication?
What is the consequence of removing RNA primers from the lagging strand?
What is the consequence of removing RNA primers from the lagging strand?
What is the sequence of the telomere DNA repeat synthesized by telomerase?
What is the sequence of the telomere DNA repeat synthesized by telomerase?
What is the directionality of polymerase a (primase) when synthesizing a RNA primer?
What is the directionality of polymerase a (primase) when synthesizing a RNA primer?
What is the consequence of telomerase synthesizing telomeric repeats continuously?
What is the consequence of telomerase synthesizing telomeric repeats continuously?
What is the role of RNase H & FEN1 in DNA replication?
What is the role of RNase H & FEN1 in DNA replication?
Why is it better for telomerase to synthesize telomeric repeats and lose a few bases?
Why is it better for telomerase to synthesize telomeric repeats and lose a few bases?
What is the role of telomerase in DNA replication?
What is the role of telomerase in DNA replication?
What is the directionality of polymerase when adding nucleotides to DNA?
What is the directionality of polymerase when adding nucleotides to DNA?
In which type of cells does telomerase synthesize telomeric repeats continuously?
In which type of cells does telomerase synthesize telomeric repeats continuously?
What is the role of polymerase a (primase) in DNA replication?
What is the role of polymerase a (primase) in DNA replication?
Which polymerase fills the gap till it hits the 5’ end of the lagging strand?
Which polymerase fills the gap till it hits the 5’ end of the lagging strand?
What is the role of ligase in DNA replication?
What is the role of ligase in DNA replication?
What is the consequence of removing RNA primers from the lagging strand?
What is the consequence of removing RNA primers from the lagging strand?
What is the sequence of the telomere DNA repeat synthesized by telomerase?
What is the sequence of the telomere DNA repeat synthesized by telomerase?
What is the directionality of polymerase a (primase) when synthesizing a RNA primer?
What is the directionality of polymerase a (primase) when synthesizing a RNA primer?
What is the consequence of telomerase synthesizing telomeric repeats continuously?
What is the consequence of telomerase synthesizing telomeric repeats continuously?
What is the role of RNase H & FEN1 in DNA replication?
What is the role of RNase H & FEN1 in DNA replication?
Why is it better for telomerase to synthesize telomeric repeats and lose a few bases?
Why is it better for telomerase to synthesize telomeric repeats and lose a few bases?
What is the function of telomerase?
What is the function of telomerase?
What is the direction in which polymerase can add nucleotides?
What is the direction in which polymerase can add nucleotides?
What is the role of Polymerase a (primase) in telomere synthesis?
What is the role of Polymerase a (primase) in telomere synthesis?
What is the role of DNA Polymerase d (pol d) in telomere synthesis?
What is the role of DNA Polymerase d (pol d) in telomere synthesis?
What is the role of Ligase in telomere synthesis?
What is the role of Ligase in telomere synthesis?
What is the reason for telomerase to synthesize telomeric repeats continuously in eukaryotic germ cells?
What is the reason for telomerase to synthesize telomeric repeats continuously in eukaryotic germ cells?
What happens to the RNA primer after the gap in the lagging strand is filled by Polymerase d?
What happens to the RNA primer after the gap in the lagging strand is filled by Polymerase d?
Why does telomerase synthesize telomeric repeats at the 3' end of the leading strand instead of filling the gap in the lagging strand?
Why does telomerase synthesize telomeric repeats at the 3' end of the leading strand instead of filling the gap in the lagging strand?
What is the consequence of telomerase synthesizing telomeric repeats instead of filling the gap in the lagging strand?
What is the consequence of telomerase synthesizing telomeric repeats instead of filling the gap in the lagging strand?
What is the direction of nucleotide addition during telomere synthesis?
What is the direction of nucleotide addition during telomere synthesis?
What is the function of RNase H in telomere synthesis?
What is the function of RNase H in telomere synthesis?
What is the function of FEN1 in telomere synthesis?
What is the function of FEN1 in telomere synthesis?
