TB Treatment Protocols and Guidelines
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Questions and Answers

What is the initial dosage of Prednisolone for treating TB pericarditis?

  • 15mg
  • 5mg
  • 30mg
  • 60mg (correct)
  • Which treatment duration is recommended for bacteriologically confirmed TB pericarditis?

  • 8 weeks
  • 6 weeks
  • 10 weeks
  • 14 days (correct)
  • What is a key benefit of patient-centered directly observed therapy (DOT) for TB treatment?

  • It increases treatment default rates.
  • It is always administered at health facilities.
  • It enhances completion of treatment. (correct)
  • It requires longer treatment durations.
  • What dosage of dexamethasone is recommended for treating TB meningitis?

    <p>0.4 mg/kg/24 hours</p> Signup and view all the answers

    What action should be taken for patients who miss treatment appointments?

    <p>Provide a default reminder letter or home visit.</p> Signup and view all the answers

    What is the definition of multidrug resistant TB (MDRTB)?

    <p>Resistance to both Isoniazid and Rifampicin</p> Signup and view all the answers

    Which baseline laboratory examination is recommended before starting anti TB treatment?

    <p>ALT and serum creatinine</p> Signup and view all the answers

    What is the classification of TB based on drug susceptibility involving resistance to one first line anti TB drug (excluding rifampicin)?

    <p>Mono resistant TB</p> Signup and view all the answers

    What individual is classified as a bacteriologically-confirmed patient with completed treatment?

    <p>One with no follow-up sputum smear or culture results.</p> Signup and view all the answers

    Which group of patients should have baseline ALT and serum creatinine requested in resource-limited settings?

    <p>Patients over 60 years and those with risk factors</p> Signup and view all the answers

    What is the minimum value for ALT in the presence of symptoms that necessitates stopping all medications immediately?

    <p>Greater than 3x the upper limit of normal.</p> Signup and view all the answers

    What is NOT recommended for screening for diabetes in TB patients according to the current guidelines?

    <p>HBA1c</p> Signup and view all the answers

    When should medications be resumed for a patient whose sputum smear is positive after five months of treatment?

    <p>Once symptoms are resolved and ALT normalizes to less than twice the ULN.</p> Signup and view all the answers

    What is polydrug resistant TB defined as?

    <p>Resistance to more than one first line anti TB drug excluding both Isoniazid and Rifampicin</p> Signup and view all the answers

    Which medication should be permanently discontinued if the patient is undergoing treatment?

    <p>Pyrazinamide</p> Signup and view all the answers

    Who should be offered counseling and testing for HIV when diagnosed with TB?

    <p>Patients with a history of high-risk behavior for HIV</p> Signup and view all the answers

    What condition qualifies a patient as clinically diagnosed but unable to have a sputum examination?

    <p>Failure to perform sputum tests due to operational issues.</p> Signup and view all the answers

    What is the classification for TB resistance that only includes resistance to one first line anti TB drug except rifampicin?

    <p>Mono resistant TB</p> Signup and view all the answers

    What is the first drug that may be restarted during a stepwise reintroduction of anti-TB drugs?

    <p>Rifampicin</p> Signup and view all the answers

    In which case should all medications be stopped immediately?

    <p>When ALT exceeds 3x the upper limit in the presence of symptoms.</p> Signup and view all the answers

    What should be offered to patients undergoing treatment as part of an incentive?

    <p>Nutritious, culturally appropriate daily meals.</p> Signup and view all the answers

    What should be done if a patient experiences a generalized erythematous rash along with fever or mucous membrane involvement while on TB medications?

    <p>STOP ALL DRUGS IMMEDIATELY</p> Signup and view all the answers

    Which TB medication is most likely to cause thrombocytopenia indicated by petechial rashes?

    <p>RIFAMPICIN</p> Signup and view all the answers

    What is the recommended approach when re-challenging a patient with a previous drug sensitization?

    <p>Start with the drug least likely to cause a reaction</p> Signup and view all the answers

    What is the gold standard for diagnosing tuberculosis?

    <p>Sputum culture</p> Signup and view all the answers

    In the management of nephrotoxicity from TB medications, which of the following is NOT routinely required?

    <p>Routine renal function monitoring in asymptomatic patients</p> Signup and view all the answers

    What duration of treatment is typically required for tuberculosis?

    <p>6-12 months</p> Signup and view all the answers

    Which TB medication should be discontinued if a patient develops nephrotoxicity?

    <p>RIFAMPICIN</p> Signup and view all the answers

    What symptoms should prompt further testing for nephrotoxicity in patients taking TB medications?

    <p>Oliguria and edema</p> Signup and view all the answers

    What should be monitored in all individuals receiving INH?

    <p>Signs of peripheral neuropathy</p> Signup and view all the answers

    What is the recommended treatment to prevent INH induced neuropathy?

    <p>Pyridoxine (Vitamin B6)</p> Signup and view all the answers

    Which major adverse reaction requires discontinuing all drugs?

    <p>Severe skin rash due to hypersensitivity</p> Signup and view all the answers

    What is a common gastrointestinal symptom experienced during the initial weeks of treatment?

    <p>Nausea</p> Signup and view all the answers

    In case of visual impairment due to TB medications, testing should focus on changes in which areas?

    <p>Visual acuity and color perception</p> Signup and view all the answers

    Which of the following symptoms warrant a referral to an ENT specialist?

    <p>Symptoms of ototoxicity from Streptomycin</p> Signup and view all the answers

    What is not necessary for liver function monitoring in asymptomatic patients on TB medications?

    <p>Routine liver function monitoring</p> Signup and view all the answers

    Which symptom is associated with positive identification of hyperuricemia in TB treatment?

    <p>Gouty arthritis</p> Signup and view all the answers

    What is recommended if a patient experiences prolonged gastrointestinal adverse drug reactions?

    <p>Administer antacids</p> Signup and view all the answers

    Managment of minor adverse reactions can involve which of the following?

    <p>Symptomatic management without stopping first-line drugs</p> Signup and view all the answers

    Which of the following describes the effect of food intake on TB medications?

    <p>Food can affect bioavailability of several anti-TB medications</p> Signup and view all the answers

    What is a minor adverse reaction that may occur with anti-TB drugs?

    <p>Localized skin reactions</p> Signup and view all the answers

    Which risk factor increases the likelihood of developing peripheral neuropathy when treated with INH?

    <p>Diabetes Mellitus</p> Signup and view all the answers

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