TB Treatment Protocols and Guidelines
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Questions and Answers

What is the initial dosage of Prednisolone for treating TB pericarditis?

  • 15mg
  • 5mg
  • 30mg
  • 60mg (correct)

Which treatment duration is recommended for bacteriologically confirmed TB pericarditis?

  • 8 weeks
  • 6 weeks
  • 10 weeks
  • 14 days (correct)

What is a key benefit of patient-centered directly observed therapy (DOT) for TB treatment?

  • It increases treatment default rates.
  • It is always administered at health facilities.
  • It enhances completion of treatment. (correct)
  • It requires longer treatment durations.

What dosage of dexamethasone is recommended for treating TB meningitis?

<p>0.4 mg/kg/24 hours (A)</p> Signup and view all the answers

What action should be taken for patients who miss treatment appointments?

<p>Provide a default reminder letter or home visit. (A)</p> Signup and view all the answers

What is the definition of multidrug resistant TB (MDRTB)?

<p>Resistance to both Isoniazid and Rifampicin (A)</p> Signup and view all the answers

Which baseline laboratory examination is recommended before starting anti TB treatment?

<p>ALT and serum creatinine (D)</p> Signup and view all the answers

What is the classification of TB based on drug susceptibility involving resistance to one first line anti TB drug (excluding rifampicin)?

<p>Mono resistant TB (D)</p> Signup and view all the answers

What individual is classified as a bacteriologically-confirmed patient with completed treatment?

<p>One with no follow-up sputum smear or culture results. (B)</p> Signup and view all the answers

Which group of patients should have baseline ALT and serum creatinine requested in resource-limited settings?

<p>Patients over 60 years and those with risk factors (D)</p> Signup and view all the answers

What is the minimum value for ALT in the presence of symptoms that necessitates stopping all medications immediately?

<p>Greater than 3x the upper limit of normal. (D)</p> Signup and view all the answers

What is NOT recommended for screening for diabetes in TB patients according to the current guidelines?

<p>HBA1c (C)</p> Signup and view all the answers

When should medications be resumed for a patient whose sputum smear is positive after five months of treatment?

<p>Once symptoms are resolved and ALT normalizes to less than twice the ULN. (D)</p> Signup and view all the answers

What is polydrug resistant TB defined as?

<p>Resistance to more than one first line anti TB drug excluding both Isoniazid and Rifampicin (D)</p> Signup and view all the answers

Which medication should be permanently discontinued if the patient is undergoing treatment?

<p>Pyrazinamide (A)</p> Signup and view all the answers

Who should be offered counseling and testing for HIV when diagnosed with TB?

<p>Patients with a history of high-risk behavior for HIV (D)</p> Signup and view all the answers

What condition qualifies a patient as clinically diagnosed but unable to have a sputum examination?

<p>Failure to perform sputum tests due to operational issues. (B)</p> Signup and view all the answers

What is the classification for TB resistance that only includes resistance to one first line anti TB drug except rifampicin?

<p>Mono resistant TB (C)</p> Signup and view all the answers

What is the first drug that may be restarted during a stepwise reintroduction of anti-TB drugs?

<p>Rifampicin (D)</p> Signup and view all the answers

In which case should all medications be stopped immediately?

<p>When ALT exceeds 3x the upper limit in the presence of symptoms. (C)</p> Signup and view all the answers

What should be offered to patients undergoing treatment as part of an incentive?

<p>Nutritious, culturally appropriate daily meals. (A)</p> Signup and view all the answers

What should be done if a patient experiences a generalized erythematous rash along with fever or mucous membrane involvement while on TB medications?

<p>STOP ALL DRUGS IMMEDIATELY (A)</p> Signup and view all the answers

Which TB medication is most likely to cause thrombocytopenia indicated by petechial rashes?

<p>RIFAMPICIN (D)</p> Signup and view all the answers

What is the recommended approach when re-challenging a patient with a previous drug sensitization?

<p>Start with the drug least likely to cause a reaction (D)</p> Signup and view all the answers

What is the gold standard for diagnosing tuberculosis?

<p>Sputum culture (B)</p> Signup and view all the answers

In the management of nephrotoxicity from TB medications, which of the following is NOT routinely required?

<p>Routine renal function monitoring in asymptomatic patients (B)</p> Signup and view all the answers

What duration of treatment is typically required for tuberculosis?

<p>6-12 months (D)</p> Signup and view all the answers

Which TB medication should be discontinued if a patient develops nephrotoxicity?

<p>RIFAMPICIN (A), STREPTOMYCIN (D)</p> Signup and view all the answers

What symptoms should prompt further testing for nephrotoxicity in patients taking TB medications?

<p>Oliguria and edema (C)</p> Signup and view all the answers

What should be monitored in all individuals receiving INH?

<p>Signs of peripheral neuropathy (A)</p> Signup and view all the answers

What is the recommended treatment to prevent INH induced neuropathy?

<p>Pyridoxine (Vitamin B6) (B)</p> Signup and view all the answers

Which major adverse reaction requires discontinuing all drugs?

<p>Severe skin rash due to hypersensitivity (B)</p> Signup and view all the answers

What is a common gastrointestinal symptom experienced during the initial weeks of treatment?

<p>Nausea (B)</p> Signup and view all the answers

In case of visual impairment due to TB medications, testing should focus on changes in which areas?

<p>Visual acuity and color perception (A)</p> Signup and view all the answers

Which of the following symptoms warrant a referral to an ENT specialist?

<p>Symptoms of ototoxicity from Streptomycin (C)</p> Signup and view all the answers

What is not necessary for liver function monitoring in asymptomatic patients on TB medications?

<p>Routine liver function monitoring (A)</p> Signup and view all the answers

Which symptom is associated with positive identification of hyperuricemia in TB treatment?

<p>Gouty arthritis (B)</p> Signup and view all the answers

What is recommended if a patient experiences prolonged gastrointestinal adverse drug reactions?

<p>Administer antacids (C)</p> Signup and view all the answers

Managment of minor adverse reactions can involve which of the following?

<p>Symptomatic management without stopping first-line drugs (B)</p> Signup and view all the answers

Which of the following describes the effect of food intake on TB medications?

<p>Food can affect bioavailability of several anti-TB medications (B)</p> Signup and view all the answers

What is a minor adverse reaction that may occur with anti-TB drugs?

<p>Localized skin reactions (D)</p> Signup and view all the answers

Which risk factor increases the likelihood of developing peripheral neuropathy when treated with INH?

<p>Diabetes Mellitus (D)</p> Signup and view all the answers

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