15 Questions
Which pathway is associated with the negative symptoms of schizophrenia?
Mesocortical Dopamine Pathway
What effect do first-generation antipsychotics have on negative symptoms of schizophrenia?
Worsen negative symptoms
Which receptor family is dopamine regulated by in the context of schizophrenia?
D2 family (D2, D3, D4)
What is the biggest predictor of an individual's ability to live independently with schizophrenia?
Negative symptoms
Which pathway is related to emotional behaviors, motivation, and pleasure in the context of schizophrenia?
Mesolimbic Dopamine Pathway
What side effect can occur due to chronic D2 antagonism in the nigrostriatal pathway?
Tardive dyskinesia
Which neurotransmitter pathway is implicated in the negative symptoms of schizophrenia?
Mesocortical pathway
What is the main impact of first-generation antipsychotics on negative symptoms of schizophrenia?
Worsen negative symptoms
What is the primary function of the Dorsolateral prefrontal cortex in the context of schizophrenia?
Regulate cognition and executive function
Which receptor family is targeted by first-generation antipsychotics?
D2 receptor
What symptom is worsened by chronic D2 antagonism in the nigrostriatal pathway?
Tardive dyskinesia
Which part of the brain does the Mesolimbic pathway connect to in the context of schizophrenia?
Ventral striatum
What is the role of the Mesocortical Dopamine Pathway in schizophrenia?
Regulate cognition and executive function
How do first-generation antipsychotics affect positive and negative symptoms of schizophrenia?
Reduce positive symptoms and increase negative symptoms
Atypical antipsychotics have a pharmacological action of:
5-HT2A Antagonism
Test your knowledge on Tardive Dyskinesia and the Basal Ganglia pathways involved in motor control. Questions cover the direct and indirect pathways, dopamine effects, and the structures responsible for modulating movements.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
