Take the NDPH Quiz

Study Notes

New Daily Persistent Headache: Clinical Findings, Precipitating Factors, and Pathogenesis

New daily persistent headache (NDPH) is characterized by sudden onset headache that continues without remission.
NDPH patients can pinpoint the exact date their headache started, which is necessary for diagnosis.
NDPH is mostly bilateral in location and can occur anywhere in the head with mild to severe intensity.
The pain is constant and lacks special characteristic features but in some has characteristics of migraine.
NDPH typically develops in individuals with no or insignificant previous headache history, but prior episodic headache does not exclude diagnosis if NDPH is different.
Comorbid symptoms in NDPH patients include sleep disturbances, light-headedness, blurred vision, neck stiffness, and mood disorders.
Precipitating factors for NDPH include infection, stressful life events, surgical procedures with intubation, and other triggers such as medication exposure and thyroid diseases.
Some studies suggest that a significant portion of NDPH patients experienced infection or a flu-like illness at the onset of headache, with Epstein-Barr virus (EBV) infection potentially playing a role in pathogenesis.
Recognition of precipitating events may help understand NDPH pathogenesis.
In a study of 97 NDPH patients, 53% could not recognize a precipitating factor.
In a study of 40 pediatric headache patients with NDPH, precipitating events were noted in 88%, with febrile illness being the most common.
The pathogenesis of NDPH is poorly understood, with few studies conducted on the topic.

Description

Test your knowledge of new daily persistent headache (NDPH) with this informative quiz. Learn about the clinical findings, precipitating factors, and potential pathogenesis of this condition. Find out how NDPH is diagnosed, its common symptoms, and possible triggers. Challenge yourself to understand the complex pathogenesis of NDPH, and gain a better understanding of this debilitating headache disorder.