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Questions and Answers
What is the primary function of negative selection in the thymus gland during T cell maturation?
What is the primary function of negative selection in the thymus gland during T cell maturation?
- To delete T cells that do not recognize self-antigens (correct)
- To ensure that T cells can recognize a wide range of foreign antigens
- To promote the development of self-reactive T cells
- To induce positive selection of T cells with high affinity for self-antigens
What is the primary difference between CD4+ T helper cells and CD8+ cytotoxic T cells in terms of their MHC restriction?
What is the primary difference between CD4+ T helper cells and CD8+ cytotoxic T cells in terms of their MHC restriction?
- CD4+ T cells are not restricted to any MHC class, while CD8+ T cells are restricted to both MHC class I and II
- CD4+ T cells are restricted to MHC class I, while CD8+ T cells are restricted to MHC class II
- CD4+ T cells and CD8+ T cells have the same MHC class restrictions
- CD4+ T cells are restricted to MHC class II, while CD8+ T cells are restricted to MHC class I (correct)
Which of the following is a key function of T helper cells (CD4+ T cells) in the immune response?
Which of the following is a key function of T helper cells (CD4+ T cells) in the immune response?
- Recruitment of neutrophils and other innate immune cells
- Phagocytosis of pathogens and cellular debris
- Direct killing of infected or cancerous cells
- Activation of B cells to produce antibodies (correct)
What is the role of cytokines in the differentiation and maturation of T cells?
What is the role of cytokines in the differentiation and maturation of T cells?
Which of the following is a key function of regulatory T cells (Tregs) in the immune system?
Which of the following is a key function of regulatory T cells (Tregs) in the immune system?
Which of the following is a key difference between the maturation of T cells in the thymus and B cells in the bone marrow?
Which of the following is a key difference between the maturation of T cells in the thymus and B cells in the bone marrow?
Which of the following is NOT a function of Th1 helper T cells?
Which of the following is NOT a function of Th1 helper T cells?
What is the primary function of T regulatory cells (Treg)?
What is the primary function of T regulatory cells (Treg)?
Which cytokine is responsible for the differentiation of naive T helper cells (Th0) into Th17 cells?
Which cytokine is responsible for the differentiation of naive T helper cells (Th0) into Th17 cells?
Which of the following is a function of Th2 helper T cells?
Which of the following is a function of Th2 helper T cells?
What is the primary function of Th17 cells?
What is the primary function of Th17 cells?
Which of the following cytokines is produced by naive T helper cells (Th0)?
Which of the following cytokines is produced by naive T helper cells (Th0)?
What is the main function of T helper cells when stimulated by IL2?
What is the main function of T helper cells when stimulated by IL2?
Which of the following is NOT a function of T cytotoxic cells (CD8)?
Which of the following is NOT a function of T cytotoxic cells (CD8)?
What is the main mechanism through which T cytotoxic cells kill infected cells?
What is the main mechanism through which T cytotoxic cells kill infected cells?
What is the approximate ratio of T helper cells to T cytotoxic cells?
What is the approximate ratio of T helper cells to T cytotoxic cells?
Which of the following cytokines are secreted by T cytotoxic cells during their killing mechanism?
Which of the following cytokines are secreted by T cytotoxic cells during their killing mechanism?
What forms the T cell receptor (TCR) complex that helps transduce signals received by TCR to T cell activation?
What forms the T cell receptor (TCR) complex that helps transduce signals received by TCR to T cell activation?
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