T Cell Development Quiz

T Cell Development

• T cell development takes place in the thymus gland.
• The cells primarily involved in T cell development are hematopoietic stem cells, which give rise to T cell progenitors, and thymic epithelial cells.

Function of Mature T Cells

• Mature T cells are responsible for cell-mediated immunity, recognizing and eliminating infected cells or producing chemical signals that activate other immune responses.

Characteristics of T Cell Development

• One key characteristic of T cell development is the process of positive selection, where T cells that recognize self-peptides presented by MHC molecules on thymic epithelial cells are selected to mature.

Role of Thymic Epithelial Cells

• Thymic epithelial cells play a crucial role in T cell development by presenting self-peptides to developing T cells and guiding their maturation.

Crucial Process in T Cell Development

• A crucial process during T cell development is negative selection, where T cells that strongly react to self-antigens are eliminated, preventing autoimmune responses.