Systemic (Left-Sided) Hypertensive Heart Disease
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Questions and Answers

What is the consequence of the increased demands placed on the heart by hypertension?

  • Necrotizing arteriolitis
  • Berry aneurysm rupture
  • Ventricular hypertrophy (correct)
  • Intracerebral hemorrhage
  • What is a typical characteristic of hyperplastic arteriolosclerosis seen in severe hypertension?

  • Thickened, reduplicated basement membrane
  • Onion skin appearance of vessels (correct)
  • Vascular wall necrosis
  • Fibrinoid deposits in arterioles
  • What can be attributed to inadequate management of hypertension according to the data provided?

  • Hyperplastic arteriolosclerosis
  • Subarachnoid hemorrhage
  • Pathological changes in nephrons
  • 62% of cerebrovascular disease and 49% of ischaemic heart disease (correct)
  • What vascular disorder is associated with hypertension and involves the rupture of berry aneurysms?

    <p>Subarachnoid hemorrhage</p> Signup and view all the answers

    What is the consequence of persistent hypertension that can culminate in CHF and even sudden death?

    <p>Cardiac dilation</p> Signup and view all the answers

    In hypertensive heart disease, what adaptive response occurs to pressure overload?

    <p>Remodeling with added sarcomeres in parallel</p> Signup and view all the answers

    What is the pathophysiological cause of Renal disease, which is the commonest cause of secondary hypertension?

    <p>Increased activity of the renin-angiotensin system</p> Signup and view all the answers

    Which condition is associated with homogeneous, pink hyaline thickening of arteriolar walls and luminal narrowing?

    <p>Hyaline arteriolosclerosis</p> Signup and view all the answers

    What structural change is observed in muscular arteries in response to hypertension?

    <p>Smooth muscle hyperplasia</p> Signup and view all the answers

    What is the consequence of arteriolar narrowing caused by hyaline arteriosclerosis in the kidneys?

    <p>Glomerular scarring</p> Signup and view all the answers

    Which lesion occurs selectively in response to hypertension and involves collagen deposition and smooth muscle hyperplasia?

    <p>Hyaline arteriolosclerosis</p> Signup and view all the answers

    What effect does hypertension have on atherosclerosis development in large arterial blood vessels?

    <p>Accelerates its development</p> Signup and view all the answers

    What is the main cause of left atrial dilation in systemic hypertensive heart disease?

    <p>Stiffening of the left ventricle</p> Signup and view all the answers

    What is the typical heart weight in an individual with systemic hypertensive heart disease?

    <p>Above 500 g</p> Signup and view all the answers

    What is the normal range for left ventricular wall thickness in an individual without left ventricular hypertrophy?

    <p>1.2 to 1.4 cm</p> Signup and view all the answers

    Which condition is characterized by marked dilation and hypertrophy of the right ventricle with thickened free wall?

    <p>Chronic cor pulmonale</p> Signup and view all the answers

    What effect does increased left ventricular wall thickness have on diastolic filling in hypertensive heart disease?

    <p>Impairs diastolic filling</p> Signup and view all the answers

    In long-standing systemic hypertensive heart disease, what happens to the hypertrophic left ventricle?

    <p>It typically becomes dilated</p> Signup and view all the answers

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