Podcast
Questions and Answers
A systematic review's purpose is always specific to one clinical question.
A systematic review's purpose is always specific to one clinical question.
False
Inclusion and exclusion criteria in a systematic review are defined for patients, not studies.
Inclusion and exclusion criteria in a systematic review are defined for patients, not studies.
False
A systematic review can only inform clinical practice if it directly addresses your clinical question.
A systematic review can only inform clinical practice if it directly addresses your clinical question.
False
Outcome measures in a systematic review are always relevant to your clinical question.
Outcome measures in a systematic review are always relevant to your clinical question.
Signup and view all the answers
Statistical heterogeneity is not a necessary consideration in a meta-analysis.
Statistical heterogeneity is not a necessary consideration in a meta-analysis.
Signup and view all the answers
The purpose of a systematic review is usually stated at the beginning of the Introduction.
The purpose of a systematic review is usually stated at the beginning of the Introduction.
Signup and view all the answers
A systematic review can only provide evidence to support one specific treatment strategy.
A systematic review can only provide evidence to support one specific treatment strategy.
Signup and view all the answers
The inclusion and exclusion criteria in a systematic review are only relevant to the study types included.
The inclusion and exclusion criteria in a systematic review are only relevant to the study types included.
Signup and view all the answers
Primary studies are also known as 'studies of studies'.
Primary studies are also known as 'studies of studies'.
Signup and view all the answers
A systematic review can only be conducted if all the included studies have the same outcome measures.
A systematic review can only be conducted if all the included studies have the same outcome measures.
Signup and view all the answers
A meta-analysis is a statistical method used to conduct primary studies.
A meta-analysis is a statistical method used to conduct primary studies.
Signup and view all the answers
Determining the applicability of a systematic review involves evaluating the quality of the studies included.
Determining the applicability of a systematic review involves evaluating the quality of the studies included.
Signup and view all the answers
A comprehensive literature search is only necessary for systematic reviews, not for primary studies.
A comprehensive literature search is only necessary for systematic reviews, not for primary studies.
Signup and view all the answers
Clinical heterogeneity is always assessed in a meta-analysis.
Clinical heterogeneity is always assessed in a meta-analysis.
Signup and view all the answers
Systematic reviews are always extended by pooling data from several studies in a process of meta-analysis.
Systematic reviews are always extended by pooling data from several studies in a process of meta-analysis.
Signup and view all the answers
The purpose of a systematic review is to provide a brief summary of a single primary study.
The purpose of a systematic review is to provide a brief summary of a single primary study.
Signup and view all the answers
A systematic review is a type of interventional study.
A systematic review is a type of interventional study.
Signup and view all the answers
The Cochrane Collaboration Guidelines are used to appraise the quality of systematic reviews.
The Cochrane Collaboration Guidelines are used to appraise the quality of systematic reviews.
Signup and view all the answers
Determining applicability is a step in critically appraising research evidence.
Determining applicability is a step in critically appraising research evidence.
Signup and view all the answers
A literature search is conducted in Step 3 of the EBP process.
A literature search is conducted in Step 3 of the EBP process.
Signup and view all the answers
Summarizing the clinical bottom line is a step in critically appraising research evidence.
Summarizing the clinical bottom line is a step in critically appraising research evidence.
Signup and view all the answers
Evaluating study quality is a step in critically appraising research evidence.
Evaluating study quality is a step in critically appraising research evidence.
Signup and view all the answers
Applying reviews to clinical cases is a step in the EBP process.
Applying reviews to clinical cases is a step in the EBP process.
Signup and view all the answers
Interpreting results is a step in critically appraising research evidence.
Interpreting results is a step in critically appraising research evidence.
Signup and view all the answers
Study Notes
Systematic Review Appraisal
- A systematic review is a secondary research study that summarizes information from multiple primary studies.
- It is characterized by a comprehensive literature search, specific inclusion and exclusion criteria, and a systematic analysis of the methodological quality of the studies.
Key Questions for Appraising Systematic Reviews
-
A: Determining Applicability of a Systematic Review
- Is the study’s purpose relevant to my clinical question?
- Are the inclusion and exclusion criteria clearly defined and are studies that would answer my clinical question likely to be included?
- Are the types of interventions investigated relevant to my clinical question?
- Are the outcome measures relevant to my clinical question and are they conducted in a clinically realist manner?
- Is the study population (sample) sufficiently similar to my patient to justify expectation that my patient would respond similarly to the population?
-
B: Determining Quality of a Systematic Review
- Was the literature search comprehensive?
- Was an objective, reproducible, and reliable method used to judge the quality of the studies in the systematic review?
- Was a standardized method used to extract data from studies included in the systematic review?
- Was clinical heterogeneity assessed to determine whether a meta-analysis was justified?
Interpreting Results of a Systematic Review
- Statistical heterogeneity should be assessed if a meta-analysis was conducted.
- Methods used to report the results of the systematic review should be considered.
Summarizing the Clinical Bottom Line of a Systematic Review
- How does the systematic review inform clinical practice related to my clinical question?
Evidence-Based Practice (EBP) Process
- Step 1: Identify the need for information and develop a focused and searchable clinical question.
- Step 2: Conduct a search to find the best possible research evidence to answer the question.
- Step 3: Critically appraise the research evidence for applicability and quality.
- Step 4: Integrate the critically appraised research evidence with clinical expertise and the patient’s values and circumstances.
- Step 5: Evaluate the effectiveness and efficacy of the efforts in Steps 1-4 and identify ways to improve them in the future.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Evaluate the relevance and applicability of a systematic review study to your clinical question. Assess the study's purpose, methods, and results to inform your clinical practice.
