Podcast
Questions and Answers
Which class of biomaterials involves physical combinations of metallic, ceramic, and polymeric materials?
Which class of biomaterials involves physical combinations of metallic, ceramic, and polymeric materials?
- Ceramic
- Polymeric
- Composites (correct)
- Metallic
What is the definition of a biomaterial?
What is the definition of a biomaterial?
- A material intended to interact with non-biological systems
- A non-viable material used in a medical device, intended to interact with biological systems (correct)
- A viable material used in medical devices
- A material exclusively used in orthopedic applications
In which lecture outline topic would you expect to learn about degradable and non-degradable polymers?
In which lecture outline topic would you expect to learn about degradable and non-degradable polymers?
- Polymerization mechanisms
- Definitions & Market of biomaterials
- Basic principles in polymer science
- Synthetic polymeric biomaterials (correct)
Which application is NOT mentioned as an application of biomaterials?
Which application is NOT mentioned as an application of biomaterials?
Why is it important for biomaterial scientists to understand the basics of polymer science?
Why is it important for biomaterial scientists to understand the basics of polymer science?
Which lecture outline topic covers the growing medical demand and expanding market for biomaterials?
Which lecture outline topic covers the growing medical demand and expanding market for biomaterials?
Which class of biomaterials is mentioned as requiring the use of multiple classes to achieve desired functional outcomes?
Which class of biomaterials is mentioned as requiring the use of multiple classes to achieve desired functional outcomes?
Which type of polymer is formed by covalently crosslinking individual polymer chains?
Which type of polymer is formed by covalently crosslinking individual polymer chains?
What does tacticity refer to in polymer chains?
What does tacticity refer to in polymer chains?
Which temperature characterizes the amorphous region of a polymer system?
Which temperature characterizes the amorphous region of a polymer system?
What holds polymer chains together in a polymer system?
What holds polymer chains together in a polymer system?
Which type of polymerization mechanism involves the combination of two monomers with the loss of a small molecule?
Which type of polymerization mechanism involves the combination of two monomers with the loss of a small molecule?
In what state do semi-crystalline polymers exist?
In what state do semi-crystalline polymers exist?
What affects the physical properties of a polymer system?
What affects the physical properties of a polymer system?
Which technique is used for controlling cross-linking in polymers?
Which technique is used for controlling cross-linking in polymers?
What is the dominant factor influencing abiotic degradation of polymers?
What is the dominant factor influencing abiotic degradation of polymers?
What is the main difference between degradation and erosion of polymers?
What is the main difference between degradation and erosion of polymers?
What are the benefits of degradable polymers for temporary implants?
What are the benefits of degradable polymers for temporary implants?
What is the regulatory consideration for degradable biomaterials and safety concerns?
What is the regulatory consideration for degradable biomaterials and safety concerns?
Which type of polymers are examples of degradable polymers in clinical use or under investigation?
Which type of polymers are examples of degradable polymers in clinical use or under investigation?
What are the methods for controlling crystallinity in polymers?
What are the methods for controlling crystallinity in polymers?
Which synthetic polyesters include PLA, PGA, and PLGA?
Which synthetic polyesters include PLA, PGA, and PLGA?
What is a characteristic of PLA?
What is a characteristic of PLA?
What is a characteristic of PGA?
What is a characteristic of PGA?
How is PLGA identified?
How is PLGA identified?
What are the examples of non-degradable polymers provided in the text?
What are the examples of non-degradable polymers provided in the text?
What is the focus of the description of poly(acrylates) in the text?
What is the focus of the description of poly(acrylates) in the text?
What is the key factor affecting the degradation kinetics of polyesters discussed in the text?
What is the key factor affecting the degradation kinetics of polyesters discussed in the text?
What is the focus of the exploration in the text regarding the in vivo biodegradation of PLGA microspheres with different L/G monomer ratios?
What is the focus of the exploration in the text regarding the in vivo biodegradation of PLGA microspheres with different L/G monomer ratios?
What is detailed in the text regarding the requirements for dental restorative application and the selection of monomer composition?
What is detailed in the text regarding the requirements for dental restorative application and the selection of monomer composition?
Study Notes
Introduction to Synthetic Polymeric Biomaterials
- Ester bonds can be broken down by hydrolysis
- Synthetic polyesters include PLA, PGA, and PLGA
- PGA is highly crystalline with a high melting point and low solubility in organic solvents
- PLA is semi-crystalline or amorphous, more hydrophobic, and has chiral carbon atoms in the backbone
- PLGA is identified by the molar ratio of its monomers, such as PLGA 75:25
- Factors affecting degradation kinetics of polyesters are discussed
- Different types of polyesters, such as DL-PLG, DL-PLA, L-PLA, PGA, and PCL, are mentioned
- The in vivo biodegradation of PLGA microspheres with different L/G monomer ratios is explored
- Tailored properties for specific biomedical applications, such as sutures and local drug delivery, are discussed
- Examples of non-degradable polymers in clinical use or under investigation are provided, such as PMMA, polyurethane, PTFE, and silicones
- Poly(acrylates) are described, with a focus on viscosity, polymerization shrinkage, and photopolymerization
- The requirements for dental restorative application and the selection of monomer composition are detailed
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Description
Test your knowledge of synthetic polymeric biomaterials with this quiz. Explore the breakdown of ester bonds, properties of synthetic polyesters like PLA, PGA, and PLGA, factors affecting degradation kinetics, and tailored properties for biomedical applications. Delve into in vivo biodegradation, non-degradable polymers, and poly(acrylates) in dental restorative applications.
