Synaptogenesis I: Key Processes and Maturation

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10 Questions

What does the manipulation of layers affect in the lamina?

Branching

What happens when axons make choices among potential postsynaptic targets?

They differentiate into presynaptic nerve terminals.

In the animal experiment mentioned, what happens to the synapse specificity between retinal ganglion neurons and interneurons in the sutured eye?

Decreases

How do synapses continue to mature and remodel?

In response to molecular programs and neural activity.

What influences the targeting of sensory axons to discrete glomeruli in the olfactory bulb?

Olfactory receptors

What drives synapse specificity during formation?

Distinct molecules influenced by activity.

What happens when you delete a receptor gene that guides axons to specific glomeruli in the olfactory bulb?

The axons project to a different glomeruli

What is the key idea behind the regeneration of connections with specific targets after damage?

Selective formation of synapses with neurons that target specific sites.

What do inhibitory basket cells form synapses on within a neuron?

Axon initial segment

What determines which types of visual stimuli activate retinal ganglion cells?

Laminae-specific connections from interneurons and ganglion cells.

Learn about the key processes driving synapse formation, from axon targeting to synapse maturation and remodelling. Explore how molecular programs and neural activity influence synaptic structure and function.

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