Podcast
Questions and Answers
Which drug inhibits the release of noradrenaline and can cause a paradoxical increase in heart rate?
Which drug inhibits the release of noradrenaline and can cause a paradoxical increase in heart rate?
- Reserpine
- Clonidine (correct)
- Prazosin
- Propranolol
Which drug has powerful mixed vasodilatory effects, leading to a decrease in both systolic and diastolic blood pressures?
Which drug has powerful mixed vasodilatory effects, leading to a decrease in both systolic and diastolic blood pressures?
- Hexamethonium
- Prazosin (correct)
- Metyrosine
- Guanethidine
Which drug is more effective in benign prostatic hyperplasia due to its selective action on a1a receptors?
Which drug is more effective in benign prostatic hyperplasia due to its selective action on a1a receptors?
- Terazosin
- Tamsulosin (correct)
- Doxazosin
- Phentolamine
Which drug acts by blocking postsynaptic a1 receptors, resulting in vasodilation and decreased blood pressure?
Which drug acts by blocking postsynaptic a1 receptors, resulting in vasodilation and decreased blood pressure?
Which drug inhibits the synthesis of noradrenaline and can be used for the treatment of pheochromocytoma?
Which drug inhibits the synthesis of noradrenaline and can be used for the treatment of pheochromocytoma?
Flashcards
Clonidine
Clonidine
A drug that inhibits the release of noradrenaline, leading to a decrease in blood pressure. However, paradoxically, it can sometimes increase heart rate.
Prazosin
Prazosin
A medication that acts as a powerful mixed vasodilator, effectively lowering both systolic and diastolic blood pressures.
Tamsulosin
Tamsulosin
A drug specifically effective for benign prostatic hyperplasia, selectively targeting a1a receptors which are prevalent in the prostate.
Phentolamine
Phentolamine
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Metyrosine
Metyrosine
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Study Notes
Alpha-Adrenergic Antagonists
- Yohimbine inhibits the release of noradrenaline and can cause a paradoxical increase in heart rate.
Vasodilatory Effects
- Phentolamine has powerful mixed vasodilatory effects, leading to a decrease in both systolic and diastolic blood pressures.
Benign Prostatic Hyperplasia
- Tamsulosin is more effective in benign prostatic hyperplasia due to its selective action on α1a receptors.
Antihypertensive Effects
- Prazosin acts by blocking postsynaptic α1 receptors, resulting in vasodilation and decreased blood pressure.
Noradrenaline Synthesis Inhibition
- Metyrosine inhibits the synthesis of noradrenaline and can be used for the treatment of pheochromocytoma.
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Description
Test your knowledge about sympathetic depressants with this quiz. Identify medications and chemicals that act on adrenergic receptors, neuronal activity, and ganglia to depress sympathetic nervous system function.
