Supportive Care in Cancer Management

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Questions and Answers

What role does serotonin play in the genesis of acute vomiting in CINV?

  • Stimulating dopamine production
  • Activating the emetic response through 5HT3 receptors (correct)
  • Inhibiting the emetic response
  • Causing a release of histamine

What sites, besides serotonin and neurokinin-1 receptors, are targeted by antiemetics in CINV treatment?

  • Insulin receptors
  • Dopamine, muscarinic, histamine, and cannabinoid receptors (correct)
  • Glutamate receptors
  • Adrenaline receptors

When does delayed nausea/vomiting typically occur after chemotherapy administration?

  • Within the first hour
  • More than 5 days later
  • Between 24 hours and 5 days (correct)
  • Between 6-12 hours

What is anticipatory nausea/vomiting in CINV?

<p>A learned, conditioned reflex response to a stimulus (C)</p> Signup and view all the answers

Which patient-related factor increases the risk of emesis in CINV?

<p>Having a history of motion sickness (A)</p> Signup and view all the answers

What is the general approach for treating 'breakthrough' CINV?

<p>Choose a drug with a different mechanism of action (A)</p> Signup and view all the answers

What is the term used to refer to the management of complications that arise from cancer treatment?

<p>Supportive care (A)</p> Signup and view all the answers

Which of the following is an example of a chemotherapy-induced complication?

<p>Febrile neutropenia (A)</p> Signup and view all the answers

What percentage of cases do agents with a 'high' emetic risk cause emesis in if not given any prophylaxis?

<p>90% or more (D)</p> Signup and view all the answers

What is the optimal approach to managing chemotherapy-induced nausea and vomiting (CINV)?

<p>Administering adequate pharmacologic prophylaxis (B)</p> Signup and view all the answers

If a patient has insufficient control of nausea and vomiting during the first cycle of chemotherapy, what is likely to happen in subsequent cycles?

<p>More difficulty in controlling emesis (A)</p> Signup and view all the answers

How is the rate of emesis during cancer treatment categorized based on individual patient risk factors and drug therapy regimen?

<p>&quot;High,&quot; &quot;moderate,&quot; &quot;low,&quot; and &quot;minimal&quot; risk levels (D)</p> Signup and view all the answers

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