Supportive Care in Cancer Management
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Questions and Answers

What role does serotonin play in the genesis of acute vomiting in CINV?

  • Stimulating dopamine production
  • Activating the emetic response through 5HT3 receptors (correct)
  • Inhibiting the emetic response
  • Causing a release of histamine

    • What sites, besides serotonin and neurokinin-1 receptors, are targeted by antiemetics in CINV treatment?

  • Insulin receptors
  • Dopamine, muscarinic, histamine, and cannabinoid receptors (correct)
  • Glutamate receptors
  • Adrenaline receptors

    • When does delayed nausea/vomiting typically occur after chemotherapy administration?

  • Within the first hour
  • More than 5 days later
  • Between 24 hours and 5 days (correct)
  • Between 6-12 hours

    • What is anticipatory nausea/vomiting in CINV?

    <p>A learned, conditioned reflex response to a stimulus</p> Signup and view all the answers

    Which patient-related factor increases the risk of emesis in CINV?

    <p>Having a history of motion sickness</p> Signup and view all the answers

    What is the general approach for treating 'breakthrough' CINV?

    <p>Choose a drug with a different mechanism of action</p> Signup and view all the answers

    What is the term used to refer to the management of complications that arise from cancer treatment?

    <p>Supportive care</p> Signup and view all the answers

    Which of the following is an example of a chemotherapy-induced complication?

    <p>Febrile neutropenia</p> Signup and view all the answers

    What percentage of cases do agents with a 'high' emetic risk cause emesis in if not given any prophylaxis?

    <p>90% or more</p> Signup and view all the answers

    What is the optimal approach to managing chemotherapy-induced nausea and vomiting (CINV)?

    <p>Administering adequate pharmacologic prophylaxis</p> Signup and view all the answers

    If a patient has insufficient control of nausea and vomiting during the first cycle of chemotherapy, what is likely to happen in subsequent cycles?

    <p>More difficulty in controlling emesis</p> Signup and view all the answers

    How is the rate of emesis during cancer treatment categorized based on individual patient risk factors and drug therapy regimen?

    <p>&quot;High,&quot; &quot;moderate,&quot; &quot;low,&quot; and &quot;minimal&quot; risk levels</p> Signup and view all the answers

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