Podcast
Questions and Answers
What role does serotonin play in the genesis of acute vomiting in CINV?
What role does serotonin play in the genesis of acute vomiting in CINV?
- Stimulating dopamine production
- Activating the emetic response through 5HT3 receptors (correct)
- Inhibiting the emetic response
- Causing a release of histamine
What sites, besides serotonin and neurokinin-1 receptors, are targeted by antiemetics in CINV treatment?
What sites, besides serotonin and neurokinin-1 receptors, are targeted by antiemetics in CINV treatment?
- Insulin receptors
- Dopamine, muscarinic, histamine, and cannabinoid receptors (correct)
- Glutamate receptors
- Adrenaline receptors
When does delayed nausea/vomiting typically occur after chemotherapy administration?
When does delayed nausea/vomiting typically occur after chemotherapy administration?
- Within the first hour
- More than 5 days later
- Between 24 hours and 5 days (correct)
- Between 6-12 hours
What is anticipatory nausea/vomiting in CINV?
What is anticipatory nausea/vomiting in CINV?
Which patient-related factor increases the risk of emesis in CINV?
Which patient-related factor increases the risk of emesis in CINV?
What is the general approach for treating 'breakthrough' CINV?
What is the general approach for treating 'breakthrough' CINV?
What is the term used to refer to the management of complications that arise from cancer treatment?
What is the term used to refer to the management of complications that arise from cancer treatment?
Which of the following is an example of a chemotherapy-induced complication?
Which of the following is an example of a chemotherapy-induced complication?
What percentage of cases do agents with a 'high' emetic risk cause emesis in if not given any prophylaxis?
What percentage of cases do agents with a 'high' emetic risk cause emesis in if not given any prophylaxis?
What is the optimal approach to managing chemotherapy-induced nausea and vomiting (CINV)?
What is the optimal approach to managing chemotherapy-induced nausea and vomiting (CINV)?
If a patient has insufficient control of nausea and vomiting during the first cycle of chemotherapy, what is likely to happen in subsequent cycles?
If a patient has insufficient control of nausea and vomiting during the first cycle of chemotherapy, what is likely to happen in subsequent cycles?
How is the rate of emesis during cancer treatment categorized based on individual patient risk factors and drug therapy regimen?
How is the rate of emesis during cancer treatment categorized based on individual patient risk factors and drug therapy regimen?
