Substance Use Disorders Risk Factors
24 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is NOT a risk factor for developing a substance use disorder?

  • Exposure to high-risk environments
  • Having a strong support system (correct)
  • Early use of substances
  • Family history of addiction
  • What is the primary neurotransmitter involved in the initial pleasurable effects of substance use?

  • Dopamine (correct)
  • Glutamate
  • GABA
  • Serotonin
  • Which of the following brain regions is primarily responsible for impaired decision-making and inability to resist cravings in Stage 3 of addiction?

  • Hippocampus
  • Prefrontal Cortex (correct)
  • Hypothalamus
  • Amygdala
  • Which of these statements accurately describes the changes in dopamine receptors after repeated drug use?

    <p>Dopamine receptors become less sensitive, requiring more of the substance for the same effect. (C)</p> Signup and view all the answers

    Which of the following demographics is NOT typically associated with a higher prevalence of substance use disorders?

    <p>Individuals over 65 (C)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the epidemiology of substance use disorders?

    <p>Prevalence of SUDs is relatively consistent across different cultures. (B)</p> Signup and view all the answers

    What is a key characteristic of Stage 2 of addiction?

    <p>The individual uses the substance to avoid withdrawal symptoms or emotional discomfort. (D)</p> Signup and view all the answers

    Which of the following BEST describes the pathophysiology of substance use disorders?

    <p>Substance use disorders result from disruptions in multiple brain circuits involved in reward, stress, and executive control. (C)</p> Signup and view all the answers

    Which genetic factor is NOT associated with increased risk for substance use disorders?

    <p>Family history of mental health disorders (D)</p> Signup and view all the answers

    How does early-life exposure to stressors influence risk for substance use disorders?

    <p>It alters HPA axis function, predisposing individuals to addiction. (D)</p> Signup and view all the answers

    Which of the following psychological factors can increase vulnerability to substance use disorders?

    <p>History of physical abuse (A)</p> Signup and view all the answers

    What role does peer pressure play in the risk of developing substance use disorders?

    <p>It can increase exposure to substance use and normalize behaviors. (B)</p> Signup and view all the answers

    Which neurobiological alteration significantly contributes to drug-seeking behavior?

    <p>Dysregulated reward systems (B)</p> Signup and view all the answers

    Which socioeconomic factor is correlated with higher rates of substance misuse?

    <p>Lower socioeconomic status (A)</p> Signup and view all the answers

    Which neurotransmitter is primarily associated with the reward sensation in addiction?

    <p>Dopamine (B)</p> Signup and view all the answers

    What effect does adolescent use of substances have on the brain?

    <p>It contributes to the impairment of decision-making as the brain develops. (D)</p> Signup and view all the answers

    What is one consequence of downregulation of dopamine receptors due to persistent substance use?

    <p>Increased sensitivity to negative emotions (A)</p> Signup and view all the answers

    Which of the following behaviors by parents can increase the risk of substance use in children?

    <p>Engaging in substance use themselves (A)</p> Signup and view all the answers

    How does the prefrontal cortex contribute to substance use disorders?

    <p>Impairs impulse control (B)</p> Signup and view all the answers

    What role does glutamate play in the context of addiction?

    <p>It contributes to memory and learning related to drug cues (A)</p> Signup and view all the answers

    Genetic predisposition to substance use disorders can involve variants in which types of genes?

    <p>Dopamine and opioid receptor genes (C)</p> Signup and view all the answers

    Which phase of addiction is characterized by increased stress and anxiety during withdrawal?

    <p>Withdrawal/negative affect phase (C)</p> Signup and view all the answers

    What is a potential effect of epigenetic changes due to chronic substance use?

    <p>Modification of gene expression perpetuating addictive behaviors (B)</p> Signup and view all the answers

    Which structure of the brain, when dysregulated, is associated with processing emotions and negative affect during withdrawal?

    <p>Amygdala (B)</p> Signup and view all the answers

    Flashcards

    Binge/intoxication phase

    The initial phase of substance use where dopamine spikes create a feeling of reward.

    Dopamine release

    The process by which dopamine is increased in the nucleus accumbens, affecting reward sensations.

    Sensitization

    Heightened responsiveness in reward circuits due to repeated substance exposure.

    Withdrawal phase

    Phase characterized by reduced dopamine receptor sensitivity and negative emotions.

    Signup and view all the flashcards

    Preoccupation/anticipation phase

    Dysfunction in the prefrontal cortex that impairs decision-making and impulse control.

    Signup and view all the flashcards

    Glutamate

    A neurotransmitter involved in memory and learning, linked to drug cues.

    Signup and view all the flashcards

    Epigenetic changes

    Alterations in gene expression due to chronic substance use that may perpetuate addiction.

    Signup and view all the flashcards

    Corticotropin-releasing factor (CRF)

    A factor that mediates the stress response, increasing relapse risk during withdrawal.

    Signup and view all the flashcards

    Dopamine Receptor Downregulation

    A reduction in dopamine receptor sensitivity due to chronic substance use, leading to decreased reward response.

    Signup and view all the flashcards

    Increased Sensitization

    Enhanced neural responses to cues due to repeated drug use, causing cravings and compulsive behavior.

    Signup and view all the flashcards

    Substance Use Disorders (SUDs)

    Recurrent use of substances leading to significant health and behavioral impairment.

    Signup and view all the flashcards

    Addiction

    Severe form of SUD characterized by compulsive drug-seeking despite negative consequences.

    Signup and view all the flashcards

    Risk Factors for SUDs

    Conditions that increase vulnerability, including family history, early use, and mental health issues.

    Signup and view all the flashcards

    Stages of Addiction

    The progression through which addiction develops: initial pleasure, withdrawal avoidance, craving.

    Signup and view all the flashcards

    Neurotransmitter Imbalances

    Disruptions in brain chemicals that contribute to the development of SUDs.

    Signup and view all the flashcards

    Brain Circuit Disruption

    Alterations in the brain's reward, stress, and executive control circuits due to substance use.

    Signup and view all the flashcards

    Genetic Risk Factors

    Hereditary influences that increase susceptibility to SUD.

    Signup and view all the flashcards

    Dopamine System

    Brain system affecting reward and pleasure, linked to SUD.

    Signup and view all the flashcards

    Impulsivity

    Difficulty controlling urges leading to substance misuse.

    Signup and view all the flashcards

    Mental Health Disorders

    Co-occurring conditions like depression or PTSD that increase SUD risk.

    Signup and view all the flashcards

    Peer Pressure

    Influence from friends that can encourage substance use.

    Signup and view all the flashcards

    Socioeconomic Factors

    Economic conditions linked to higher substance misuse rates.

    Signup and view all the flashcards

    Early Exposure to Substances

    Initial substance use during adolescence that leads to long-term issues.

    Signup and view all the flashcards

    Trauma History

    Past physical or emotional abuse that raises addiction risk.

    Signup and view all the flashcards

    Study Notes

    Substance Use Disorders (SUD) Risk Factors

    • Biological/Genetic:
      • Genetics play a significant role in SUD, impacting how individuals metabolize substances and their sensitivity.
      • Family history of SUD increases risk.
      • Variants in dopamine-related genes can influence vulnerability.
      • Neurobiological alterations in dopamine and glutamate systems are key.
      • Dysregulated reward systems can enhance drug-seeking behavior and impair decision-making (prefrontal cortex).

    Psychological/Behavioral Risk Factors

    • Mental Health:
      • Co-occurring conditions like depression, anxiety, PTSD, and schizophrenia increase risk.
      • Self-medication with substances is a common coping mechanism for emotional distress.
    • Impulsivity/Poor Self-Control:
      • Impaired prefrontal cortex function hinders resisting urges and controlling behavior, leading to substance misuse.
    • Trauma/Abuse History:
      • Exposure to trauma (physical, sexual, emotional) significantly increases SUD risk.
      • Early-life stressors alter HPA axis function, making individuals more susceptible to addiction.

    Social and Environmental Risk Factors

    • Peer Pressure/Social Networks:
      • Exposure to peers who use substances increases risk.
      • Social settings normalizing drug use promote habitual use.
    • Socioeconomic Factors:
      • Lower socioeconomic status is associated with higher rates of substance misuse.
      • Unemployment, lack of education, and unstable housing exacerbate stress and increase vulnerability.

    Early Exposure and Addiction

    • Adolescent Use: Prefrontal cortex development is incomplete during adolescence, making early substance use risky.
    • Parental Modeling: Children exposed to parental substance use are more likely to normalize this behavior.
    • Drug Availability: Easier access to substances increases the likelihood of use and dependence.

    Neuroplasticity and Chronic Use

    • Neuroplastic Changes: Chronic use downregulates dopamine receptors, decreasing sensitivity to rewards, and requiring more substance for the same effect.
    • Increased Sensitization: Repeated use enhances neural responses to conditioned cues, leading to cravings and compulsion.

    Epidemiology of Substance Use Disorders

    • Prevalence/Impact: SUDs involve recurrent substance use (e.g., alcohol, opioids, stimulants) leading to significant impairment.
    • Demographics/Risk Factors: Adolescents, young adults, and those with mental health disorders are at higher risk.
    • Genetics, Environment, & Psychology: These factors interact to increase vulnerability to SUDs.

    Clinical Manifestations

    • Physical Manifestations: Withdrawal symptoms include tremors, sweating, anxiety, nausea, headaches; and tolerance development requiring higher doses for the same effect.

    • Psychological Manifestations: Mood swings, anxiety, depression, impaired cognitive function, cravings.

    • Behavioral Manifestations: Compulsive drug-seeking, neglect of responsibilities, social withdrawal, risky behaviors.

    • Social/Occupational Impairments: Relationship conflicts, financial problems, legal issues.

    • Neurocircuitry of Addiction: Substance use overstimulates the mesolimbic dopamine pathway causing intense reward sensations.

    • Withdrawal/Negative Affect: Changes in stress regulation circuits causing dysphoric feelings and withdrawal symptoms, creating negative reinforcement.

    • Stages of Addiction: Initial pleasure (Stage 1), substance use for withdrawal avoidance (Stage 2), and impaired decision-making/cravings due to prefrontal cortex dysfunction (Stage 3)

    • Preoccupation/Anticipation: Cravings, compulsive drug-seeking, due to prefrontal cortex dysfunction

    • Psychological Co-morbidities: Co-existent conditions including mood disorders (e.g., depression, bipolar), anxiety disorders, and schizophrenia.

    • Long-Term Consequences: Cognitive decline, physical complications (e.g., liver damage, cardiovascular diseases), and infectious diseases.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Description

    This quiz explores the various risk factors associated with Substance Use Disorders (SUD). It covers biological, psychological, and behavioral influences that can predispose individuals to SUD, including genetics, mental health conditions, and personal history of trauma. Understanding these factors is crucial for prevention and intervention strategies.

    More Like This

    Substance Use Disorders Pt.1, Ch 14
    72 questions
    Substance Use Disorders Overview
    64 questions
    Substance Use Disorders - Quiz 14
    20 questions
    Use Quizgecko on...
    Browser
    Browser