Subscription Companies and Genome Databases
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Questions and Answers

What type of companies sell information or access to information and data that is valuable to other companies?

  • Genomic discovery companies
  • Subscription companies (correct)
  • Pharmaceutical companies
  • Service companies

Which type of companies offer solutions based on a common technology or generic tool of other large pharmaceutical or biopharmaceutical companies?

  • Platform technology companies (correct)
  • Service companies
  • Subscription companies
  • Genomic discovery companies

Which type of biotechnology companies support the preclinical, clinical, regulatory, manufacturing, marketing, distribution, and commercialization functions of large pharmaceutical companies?

  • Platform technology companies
  • Service-based companies (correct)
  • Genomic discovery companies
  • Subscription-based companies

Which subscription-based companies develop genome databases used to develop medicinal drugs?

<p>Celera and Gene Logic (C)</p> Signup and view all the answers

What do pharmaceutical companies do with the data from subscription-based companies?

<p>Subscribe to the data and pay subscription fees (A)</p> Signup and view all the answers

Which service company provides software solutions for biological data analysis?

<p>Qiagen (D)</p> Signup and view all the answers

What is the primary business model utilized by many early genomic discovery companies?

<p>Subscription business model (D)</p> Signup and view all the answers

Which type of biotechnology company is most likely to develop genome databases for medicinal purposes based on the text?

<p>Subscription-based companies (A)</p> Signup and view all the answers

What are the three major approaches of protein engineering research mentioned in the text?

<p>Directed evolution, rational design, de novo design (B)</p> Signup and view all the answers

Which method of protein engineering involves creating random mutations in the native enzyme?

<p>Directed evolution (C)</p> Signup and view all the answers

What does rational design in protein engineering require for designing variants with desired properties?

<p>All of the above (D)</p> Signup and view all the answers

Which technique involves creating mutations at computationally defined sites in the gene sequence via PCR?

<p>Site-directed mutagenesis (C)</p> Signup and view all the answers

What type of changes are controllable in rational design of proteins?

<p>All of the above (D)</p> Signup and view all the answers

Which method involves changing the functional group of the side chain in proteins?

<p>Chemical modifications (C)</p> Signup and view all the answers

In computational protein design, what knowledge is required about the protein of interest?

<p>Amino acid sequence, 3D structure, and function (C)</p> Signup and view all the answers

What are the changes put into practice by site-directed mutagenesis in protein engineering?

<p>Mutations at defined sites (A)</p> Signup and view all the answers

What category do techniques used for protein engineering fall into?

<p>Genetic modifications and chemical modifications (C)</p> Signup and view all the answers

What do directed evolution and rational design have in common as stated in the text?

<p>Noteworthy methods in protein engineering (A)</p> Signup and view all the answers

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