18 Questions
What type of companies sell information or access to information and data that is valuable to other companies?
Subscription companies
Which type of companies offer solutions based on a common technology or generic tool of other large pharmaceutical or biopharmaceutical companies?
Platform technology companies
Which type of biotechnology companies support the preclinical, clinical, regulatory, manufacturing, marketing, distribution, and commercialization functions of large pharmaceutical companies?
Service-based companies
Which subscription-based companies develop genome databases used to develop medicinal drugs?
Celera and Gene Logic
What do pharmaceutical companies do with the data from subscription-based companies?
Subscribe to the data and pay subscription fees
Which service company provides software solutions for biological data analysis?
Qiagen
What is the primary business model utilized by many early genomic discovery companies?
Subscription business model
Which type of biotechnology company is most likely to develop genome databases for medicinal purposes based on the text?
Subscription-based companies
What are the three major approaches of protein engineering research mentioned in the text?
Directed evolution, rational design, de novo design
Which method of protein engineering involves creating random mutations in the native enzyme?
Directed evolution
What does rational design in protein engineering require for designing variants with desired properties?
All of the above
Which technique involves creating mutations at computationally defined sites in the gene sequence via PCR?
Site-directed mutagenesis
What type of changes are controllable in rational design of proteins?
All of the above
Which method involves changing the functional group of the side chain in proteins?
Chemical modifications
In computational protein design, what knowledge is required about the protein of interest?
Amino acid sequence, 3D structure, and function
What are the changes put into practice by site-directed mutagenesis in protein engineering?
Mutations at defined sites
What category do techniques used for protein engineering fall into?
Genetic modifications and chemical modifications
What do directed evolution and rational design have in common as stated in the text?
Noteworthy methods in protein engineering
Explore the business model of subscription companies that provide valuable information and data, focusing on genomic discovery companies like Celera and Gene Logic. Learn how pharmaceutical companies utilize genome databases to develop medicinal drugs and pay subscription fees to access the data.
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