Subscription Companies and Genome Databases
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Questions and Answers

What type of companies sell information or access to information and data that is valuable to other companies?

  • Genomic discovery companies
  • Subscription companies (correct)
  • Pharmaceutical companies
  • Service companies
  • Which type of companies offer solutions based on a common technology or generic tool of other large pharmaceutical or biopharmaceutical companies?

  • Platform technology companies (correct)
  • Service companies
  • Subscription companies
  • Genomic discovery companies
  • Which type of biotechnology companies support the preclinical, clinical, regulatory, manufacturing, marketing, distribution, and commercialization functions of large pharmaceutical companies?

  • Platform technology companies
  • Service-based companies (correct)
  • Genomic discovery companies
  • Subscription-based companies
  • Which subscription-based companies develop genome databases used to develop medicinal drugs?

    <p>Celera and Gene Logic</p> Signup and view all the answers

    What do pharmaceutical companies do with the data from subscription-based companies?

    <p>Subscribe to the data and pay subscription fees</p> Signup and view all the answers

    Which service company provides software solutions for biological data analysis?

    <p>Qiagen</p> Signup and view all the answers

    What is the primary business model utilized by many early genomic discovery companies?

    <p>Subscription business model</p> Signup and view all the answers

    Which type of biotechnology company is most likely to develop genome databases for medicinal purposes based on the text?

    <p>Subscription-based companies</p> Signup and view all the answers

    What are the three major approaches of protein engineering research mentioned in the text?

    <p>Directed evolution, rational design, de novo design</p> Signup and view all the answers

    Which method of protein engineering involves creating random mutations in the native enzyme?

    <p>Directed evolution</p> Signup and view all the answers

    What does rational design in protein engineering require for designing variants with desired properties?

    <p>All of the above</p> Signup and view all the answers

    Which technique involves creating mutations at computationally defined sites in the gene sequence via PCR?

    <p>Site-directed mutagenesis</p> Signup and view all the answers

    What type of changes are controllable in rational design of proteins?

    <p>All of the above</p> Signup and view all the answers

    Which method involves changing the functional group of the side chain in proteins?

    <p>Chemical modifications</p> Signup and view all the answers

    In computational protein design, what knowledge is required about the protein of interest?

    <p>Amino acid sequence, 3D structure, and function</p> Signup and view all the answers

    What are the changes put into practice by site-directed mutagenesis in protein engineering?

    <p>Mutations at defined sites</p> Signup and view all the answers

    What category do techniques used for protein engineering fall into?

    <p>Genetic modifications and chemical modifications</p> Signup and view all the answers

    What do directed evolution and rational design have in common as stated in the text?

    <p>Noteworthy methods in protein engineering</p> Signup and view all the answers

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