18 Questions
Atherosclerosis is the buildup of fats or other substances such as cholesterol crystals and then macrophages in your artery walls can lead to ______ arteries narrows
plaque
Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called ______. These lesions may lead to narrowing due to buildup of the atheromatous ______
Endothelium produces NO, causing relaxation of vessels. This process is known as endothelium-mediated ______
vasodilation
In vivo assessment of endothelial dysfunction involves the application of ACh, which makes smooth muscle cells ______.
contract
The recruitment of leukocytes to the vessel wall increases the ______ process.
inflammatory
In hyperlipidemia, monocytes change from a homeostatic phenotype to a ______ phenotype, becoming potent activators of leukocytes.
proinflammatory
Therapy goal: Intervene in the early inflammatory processes when ______ cytokines are produced by macrophages.
proinflammatory
Arterial macrophages express ______ phenotype, which includes the expression of IL-1b, TNFa, and CXCL2.
inflammatory
Clonal hematopoiesis is a new independent risk factor of atherosclerosis, associated with increased ______ formation.
NET
JAK2 mutation is associated with increased ______ formation.
NET
TET2 mutation leads to epigenetic alteration of chemokines, such as IL-6, Cxcl1, 2, 3, and ______.
IL-1b
Canakinumab has been shown to reduce cardiovascular events by 64% in patients with TET2 CH and by 15% in overall patients with CVD and increased ______.
hsCRP
Atherosclerosis is a leading cause of ______
mortality
Atherosclerosis is the buildup of fats or other substances such as cholesterol crystals and then macrophages in your artery walls can lead to plaque ______ arteries narrows
narrows
Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called ______
lesions
These lesions may lead to narrowing due to buildup of the atheromatous ______
plaque
Risk factors for endothelial dysfunction include Hypertension, Physical inactivity, Aging, Smoking, and ______
Obesity
The endothelium is for ______
vascular homeostasis
This study plan outlines the schedule for covering specific pages of the ZF textbook along with accompanying slides, as well as tasks such as revising, summarizing, and generating questions using AI tools. The plan extends up to February 6, 2024.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
